EPN2

 

Full name: epsin 2 Alias Symbol: KIAA1065|EHB21
Type: protein-coding gene Cytoband: 17p11.2
Entrez ID: 22905 HGNC ID: HGNC:18639 Ensembl Gene: ENSG00000072134 OMIM ID: 607263
Drug and gene relationship at DGIdb

 

Expression of EPN2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 EPN2 22905 47490 -0.4725 0.0000
GSE53624 EPN2 22905 47490 -0.4061 0.0000
GSE97050 EPN2 22905 A_23_P89310 -0.3540 0.2974
SRP007169 EPN2 22905 RNAseq -0.6624 0.2172
SRP008496 EPN2 22905 RNAseq -0.3639 0.2135
SRP064894 EPN2 22905 RNAseq -0.5671 0.0228
SRP133303 EPN2 22905 RNAseq -0.7779 0.0000
SRP159526 EPN2 22905 RNAseq -0.6832 0.0015
SRP193095 EPN2 22905 RNAseq -0.6454 0.0006
SRP219564 EPN2 22905 RNAseq -0.8339 0.0508
TCGA EPN2 22905 RNAseq 0.1086 0.0476

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by EPN2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of EPN2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EPN2 22905 4 3 23
GSE20123 EPN2 22905 4 4 22
GSE43470 EPN2 22905 1 5 37
GSE46452 EPN2 22905 34 1 24
GSE47630 EPN2 22905 7 1 32
GSE54993 EPN2 22905 3 3 64
GSE54994 EPN2 22905 6 6 41
GSE60625 EPN2 22905 4 0 7
GSE74703 EPN2 22905 1 2 33
GSE74704 EPN2 22905 3 1 16
TCGA EPN2 22905 19 24 53

Total number of gains: 86; Total number of losses: 50; Total Number of normals: 352.  


 

Somatic mutations of EPN2:

 

Generating mutation plots.

 

Highly correlated genes for EPN2:

 

Showing top 20/37 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EPN2SLC48A10.670634303
EPN2ADAMTSL40.662699303
EPN2NDRG20.654769303
EPN2MAST40.641646303
EPN2ARL4D0.633787303
EPN2TIMM8B0.632484303
EPN2ERBB20.626231303
EPN2MAFG0.624321303
EPN2DKK40.623501303
EPN2ALS2CL0.620508303
EPN2SNX210.616533303
EPN2ACAP30.61099303
EPN2PCDH10.603557303
EPN2PHLDB30.603495403
EPN2MAPT0.602732303
EPN2ARHGAP100.601922303
EPN2AHNAK0.601358303
EPN2BDH10.599078303
EPN2TP53INP20.598199303
EPN2BLVRB0.590472303

For details and further investigation, click here