SNAPC1

 

Full name: small nuclear RNA activating complex polypeptide 1 Alias Symbol: SNAP43|PTFgamma
Type: protein-coding gene Cytoband: 14q23.2
Entrez ID: 6617 HGNC ID: HGNC:11134 Ensembl Gene: ENSG00000023608 OMIM ID: 600591
Drug and gene relationship at DGIdb

 

Expression of SNAPC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SNAPC1 6617 205443_at 1.1666 0.1726
GSE20347 SNAPC1 6617 205443_at 1.1805 0.0000
GSE23400 SNAPC1 6617 205443_at 1.1397 0.0000
GSE26886 SNAPC1 6617 205443_at 2.1688 0.0000
GSE29001 SNAPC1 6617 205443_at 1.3429 0.0040
GSE38129 SNAPC1 6617 205443_at 1.4377 0.0000
GSE45670 SNAPC1 6617 205443_at 1.3217 0.0001
GSE53622 SNAPC1 6617 23143 0.5691 0.0000
GSE53624 SNAPC1 6617 23143 0.5851 0.0006
GSE63941 SNAPC1 6617 205443_at 0.1503 0.8558
GSE77861 SNAPC1 6617 205443_at 1.7228 0.0033
GSE97050 SNAPC1 6617 A_33_P3316223 0.2648 0.2504
SRP007169 SNAPC1 6617 RNAseq 0.8608 0.0230
SRP008496 SNAPC1 6617 RNAseq 0.9168 0.0013
SRP064894 SNAPC1 6617 RNAseq 1.3258 0.0000
SRP133303 SNAPC1 6617 RNAseq 0.9150 0.0001
SRP159526 SNAPC1 6617 RNAseq 1.1370 0.0114
SRP193095 SNAPC1 6617 RNAseq 1.1615 0.0000
SRP219564 SNAPC1 6617 RNAseq 0.9726 0.0318
TCGA SNAPC1 6617 RNAseq 0.6595 0.0000

Upregulated datasets: 10; Downregulated datasets: 0.  

 

Survival by SNAPC1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SNAPC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SNAPC1 6617 9 3 18
GSE20123 SNAPC1 6617 9 3 18
GSE43470 SNAPC1 6617 8 2 33
GSE46452 SNAPC1 6617 16 3 40
GSE47630 SNAPC1 6617 11 9 20
GSE54993 SNAPC1 6617 3 9 58
GSE54994 SNAPC1 6617 19 4 30
GSE60625 SNAPC1 6617 0 2 9
GSE74703 SNAPC1 6617 7 2 27
GSE74704 SNAPC1 6617 4 2 14
TCGA SNAPC1 6617 33 14 49

Total number of gains: 119; Total number of losses: 53; Total Number of normals: 316.  

 

Somatic mutations of SNAPC1:

 

Generating mutation plots.

 

Highly correlated genes for SNAPC1:

 

Showing top 20/1290 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SNAPC1SLC5A80.751302303
SNAPC1IRX20.730481303
SNAPC1DBF40.725546909
SNAPC1SLC38A60.72223510010
SNAPC1ERCC80.718075303
SNAPC1PSMC10.715996909
SNAPC1C11orf240.7156971009
SNAPC1NUF20.715195505
SNAPC1WDR540.715049605
SNAPC1POU6F2-AS20.710177404
SNAPC1PLBD20.707646504
SNAPC1CCT6A0.7065808
SNAPC1MRGBP0.706156907
SNAPC1PAGE10.705824303
SNAPC1MRPS170.705051808
SNAPC1FMNL20.703425605
SNAPC1CMC20.701494808
SNAPC1GIGYF10.701223303
SNAPC1TMEM184B0.700673908
SNAPC1KIAA09300.699671908

For details and further investigation, click here