CDCA4

 

Full name: cell division cycle associated 4 Alias Symbol: FLJ20764|Hepp
Type: protein-coding gene Cytoband: 14q32.33
Entrez ID: 55038 HGNC ID: HGNC:14625 Ensembl Gene: ENSG00000170779 OMIM ID: 612270
Drug and gene relationship at DGIdb

 

Expression of CDCA4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CDCA4 55038 218399_s_at 0.8771 0.0529
GSE20347 CDCA4 55038 218399_s_at 0.8704 0.0000
GSE23400 CDCA4 55038 218399_s_at 0.7708 0.0000
GSE26886 CDCA4 55038 218399_s_at 0.7142 0.0017
GSE29001 CDCA4 55038 218399_s_at 0.8142 0.0040
GSE38129 CDCA4 55038 218399_s_at 1.1251 0.0000
GSE45670 CDCA4 55038 218399_s_at 0.3792 0.1055
GSE53622 CDCA4 55038 68081 0.7650 0.0000
GSE53624 CDCA4 55038 68081 0.7191 0.0000
GSE63941 CDCA4 55038 218399_s_at 2.2653 0.0001
GSE77861 CDCA4 55038 218399_s_at 0.5448 0.1019
GSE97050 CDCA4 55038 A_24_P133488 0.4957 0.3998
SRP007169 CDCA4 55038 RNAseq 0.6164 0.0584
SRP008496 CDCA4 55038 RNAseq 0.5094 0.0103
SRP064894 CDCA4 55038 RNAseq 0.7321 0.0028
SRP133303 CDCA4 55038 RNAseq 0.7508 0.0000
SRP159526 CDCA4 55038 RNAseq 1.1841 0.0078
SRP193095 CDCA4 55038 RNAseq 0.7131 0.0014
SRP219564 CDCA4 55038 RNAseq 1.1683 0.0486
TCGA CDCA4 55038 RNAseq 0.8162 0.0000

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by CDCA4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CDCA4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CDCA4 55038 11 3 16
GSE20123 CDCA4 55038 10 2 18
GSE43470 CDCA4 55038 6 4 33
GSE46452 CDCA4 55038 18 4 37
GSE47630 CDCA4 55038 10 8 22
GSE54993 CDCA4 55038 4 10 56
GSE54994 CDCA4 55038 21 4 28
GSE60625 CDCA4 55038 0 2 9
GSE74703 CDCA4 55038 5 3 28
GSE74704 CDCA4 55038 5 2 13
TCGA CDCA4 55038 32 17 47

Total number of gains: 122; Total number of losses: 59; Total Number of normals: 307.  

 

Somatic mutations of CDCA4:

 

Generating mutation plots.

 

Highly correlated genes for CDCA4:

 

Showing top 20/1639 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CDCA4PRELID10.753861303
CDCA4NEK60.741593404
CDCA4TIGD10.73961303
CDCA4TDP10.72659612011
CDCA4CDKN30.72291213012
CDCA4TMEM110.721302303
CDCA4FANCD20.720795404
CDCA4GINS10.7170312011
CDCA4UBE2C0.70501212011
CDCA4WDHD10.70408713012
CDCA4TPX20.70263612011
CDCA4HJURP0.70202912010
CDCA4FZD60.700789807
CDCA4VRK10.70071313013
CDCA4SESN30.700583303
CDCA4MELK0.6998211011
CDCA4LRP80.696997808
CDCA4IRF2BPL0.696892403
CDCA4EBNA1BP20.696756303
CDCA4SAFB20.695366303

For details and further investigation, click here