| Full name: SLX4 interacting protein | Alias Symbol: dJ1099D15.3 | ||
| Type: protein-coding gene | Cytoband: 20p12.2 | ||
| Entrez ID: 128710 | HGNC ID: HGNC:16225 | Ensembl Gene: ENSG00000149346 | OMIM ID: 615958 |
| Drug and gene relationship at DGIdb | |||
Expression of SLX4IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLX4IP | 128710 | 229615_at | 0.5790 | 0.3636 | |
| GSE26886 | SLX4IP | 128710 | 229615_at | -0.4956 | 0.1066 | |
| GSE45670 | SLX4IP | 128710 | 229615_at | 0.5674 | 0.0052 | |
| GSE53622 | SLX4IP | 128710 | 90710 | 0.6797 | 0.0000 | |
| GSE53624 | SLX4IP | 128710 | 90710 | 0.5840 | 0.0000 | |
| GSE63941 | SLX4IP | 128710 | 229615_at | 0.6727 | 0.2627 | |
| GSE77861 | SLX4IP | 128710 | 229615_at | 0.0977 | 0.6729 | |
| SRP007169 | SLX4IP | 128710 | RNAseq | 0.0485 | 0.9224 | |
| SRP008496 | SLX4IP | 128710 | RNAseq | -0.0402 | 0.8807 | |
| SRP064894 | SLX4IP | 128710 | RNAseq | 0.5819 | 0.0100 | |
| SRP133303 | SLX4IP | 128710 | RNAseq | 0.3911 | 0.0449 | |
| SRP159526 | SLX4IP | 128710 | RNAseq | 0.4468 | 0.1578 | |
| SRP193095 | SLX4IP | 128710 | RNAseq | 0.1075 | 0.3070 | |
| SRP219564 | SLX4IP | 128710 | RNAseq | 0.4021 | 0.2438 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLX4IP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SLX4IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLX4IP | 128710 | 10 | 1 | 19 | |
| GSE20123 | SLX4IP | 128710 | 10 | 1 | 19 | |
| GSE43470 | SLX4IP | 128710 | 11 | 1 | 31 | |
| GSE46452 | SLX4IP | 128710 | 26 | 1 | 32 | |
| GSE47630 | SLX4IP | 128710 | 18 | 4 | 18 | |
| GSE54993 | SLX4IP | 128710 | 1 | 14 | 55 | |
| GSE54994 | SLX4IP | 128710 | 25 | 1 | 27 | |
| GSE60625 | SLX4IP | 128710 | 0 | 0 | 11 | |
| GSE74703 | SLX4IP | 128710 | 8 | 1 | 27 | |
| GSE74704 | SLX4IP | 128710 | 5 | 1 | 14 | |
| TCGA | SLX4IP | 128710 | 43 | 11 | 42 |
Total number of gains: 157; Total number of losses: 36; Total Number of normals: 295.
Somatic mutations of SLX4IP:
Generating mutation plots.
Highly correlated genes for SLX4IP:
Showing top 20/130 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLX4IP | CDK5 | 0.701848 | 3 | 0 | 3 |
| SLX4IP | NMRAL1 | 0.681357 | 3 | 0 | 3 |
| SLX4IP | MGME1 | 0.679095 | 6 | 0 | 6 |
| SLX4IP | KDM2A | 0.665046 | 3 | 0 | 3 |
| SLX4IP | MIS18BP1 | 0.66021 | 3 | 0 | 3 |
| SLX4IP | TUFM | 0.65192 | 3 | 0 | 3 |
| SLX4IP | CCNF | 0.646711 | 4 | 0 | 3 |
| SLX4IP | RCC1 | 0.643998 | 3 | 0 | 3 |
| SLX4IP | PIGU | 0.643737 | 4 | 0 | 3 |
| SLX4IP | ANKEF1 | 0.641834 | 6 | 0 | 5 |
| SLX4IP | PFAS | 0.640699 | 3 | 0 | 3 |
| SLX4IP | MON1B | 0.633013 | 4 | 0 | 3 |
| SLX4IP | ZFP64 | 0.626297 | 6 | 0 | 4 |
| SLX4IP | TCHP | 0.62606 | 3 | 0 | 3 |
| SLX4IP | MKI67 | 0.620144 | 3 | 0 | 3 |
| SLX4IP | CSTF1 | 0.619221 | 3 | 0 | 3 |
| SLX4IP | MCM8 | 0.618747 | 6 | 0 | 6 |
| SLX4IP | KIF3B | 0.618347 | 3 | 0 | 3 |
| SLX4IP | ALG6 | 0.618211 | 4 | 0 | 3 |
| SLX4IP | MIS18A | 0.616122 | 5 | 0 | 3 |
For details and further investigation, click here
