| Full name: cleavage stimulation factor subunit 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q13.2-q13.31 | ||
| Entrez ID: 1477 | HGNC ID: HGNC:2483 | Ensembl Gene: ENSG00000101138 | OMIM ID: 600369 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CSTF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSTF1 | 1477 | 32723_at | 0.6773 | 0.1643 | |
| GSE20347 | CSTF1 | 1477 | 32723_at | 0.4858 | 0.0021 | |
| GSE23400 | CSTF1 | 1477 | 202190_at | 0.4346 | 0.0000 | |
| GSE26886 | CSTF1 | 1477 | 32723_at | 0.5292 | 0.0137 | |
| GSE29001 | CSTF1 | 1477 | 32723_at | 0.7533 | 0.0085 | |
| GSE38129 | CSTF1 | 1477 | 32723_at | 0.5074 | 0.0000 | |
| GSE45670 | CSTF1 | 1477 | 32723_at | 0.3873 | 0.0046 | |
| GSE53622 | CSTF1 | 1477 | 24152 | 0.3687 | 0.0000 | |
| GSE53624 | CSTF1 | 1477 | 24152 | 0.5675 | 0.0000 | |
| GSE63941 | CSTF1 | 1477 | 32723_at | 0.7106 | 0.0316 | |
| GSE77861 | CSTF1 | 1477 | 202190_at | 0.5707 | 0.0153 | |
| GSE97050 | CSTF1 | 1477 | A_23_P362824 | 0.4248 | 0.2204 | |
| SRP007169 | CSTF1 | 1477 | RNAseq | 0.3594 | 0.3648 | |
| SRP008496 | CSTF1 | 1477 | RNAseq | 0.5043 | 0.0237 | |
| SRP064894 | CSTF1 | 1477 | RNAseq | 0.5111 | 0.0009 | |
| SRP133303 | CSTF1 | 1477 | RNAseq | 0.5482 | 0.0000 | |
| SRP159526 | CSTF1 | 1477 | RNAseq | 0.6321 | 0.0228 | |
| SRP193095 | CSTF1 | 1477 | RNAseq | 0.1925 | 0.0256 | |
| SRP219564 | CSTF1 | 1477 | RNAseq | 0.5392 | 0.0309 | |
| TCGA | CSTF1 | 1477 | RNAseq | 0.1002 | 0.0565 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CSTF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSTF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSTF1 | 1477 | 14 | 2 | 14 | |
| GSE20123 | CSTF1 | 1477 | 14 | 2 | 14 | |
| GSE43470 | CSTF1 | 1477 | 13 | 0 | 30 | |
| GSE46452 | CSTF1 | 1477 | 29 | 0 | 30 | |
| GSE47630 | CSTF1 | 1477 | 24 | 1 | 15 | |
| GSE54993 | CSTF1 | 1477 | 0 | 17 | 53 | |
| GSE54994 | CSTF1 | 1477 | 27 | 0 | 26 | |
| GSE60625 | CSTF1 | 1477 | 0 | 0 | 11 | |
| GSE74703 | CSTF1 | 1477 | 11 | 0 | 25 | |
| GSE74704 | CSTF1 | 1477 | 11 | 0 | 9 | |
| TCGA | CSTF1 | 1477 | 43 | 4 | 49 |
Total number of gains: 186; Total number of losses: 26; Total Number of normals: 276.
Somatic mutations of CSTF1:
Generating mutation plots.
Highly correlated genes for CSTF1:
Showing top 20/1602 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSTF1 | NELFCD | 0.764468 | 11 | 0 | 11 |
| CSTF1 | CSE1L | 0.742731 | 12 | 0 | 11 |
| CSTF1 | RAE1 | 0.726805 | 12 | 0 | 10 |
| CSTF1 | DPM1 | 0.722353 | 12 | 0 | 11 |
| CSTF1 | PFDN4 | 0.713142 | 12 | 0 | 12 |
| CSTF1 | DSN1 | 0.712134 | 11 | 0 | 11 |
| CSTF1 | HPS3 | 0.711134 | 4 | 0 | 4 |
| CSTF1 | TIGD2 | 0.700076 | 5 | 0 | 5 |
| CSTF1 | ZNF622 | 0.698872 | 5 | 0 | 4 |
| CSTF1 | PSMA7 | 0.691375 | 11 | 0 | 9 |
| CSTF1 | EARS2 | 0.68949 | 5 | 0 | 5 |
| CSTF1 | GINS1 | 0.687859 | 12 | 0 | 11 |
| CSTF1 | CENPBD1 | 0.687401 | 5 | 0 | 4 |
| CSTF1 | DUS3L | 0.686468 | 3 | 0 | 3 |
| CSTF1 | PDPR | 0.686392 | 4 | 0 | 4 |
| CSTF1 | ZNF670 | 0.685075 | 5 | 0 | 5 |
| CSTF1 | PRIM1 | 0.684273 | 12 | 0 | 11 |
| CSTF1 | CDK5RAP1 | 0.682613 | 10 | 0 | 10 |
| CSTF1 | KTI12 | 0.68191 | 3 | 0 | 3 |
| CSTF1 | YTHDF1 | 0.681269 | 12 | 0 | 12 |
For details and further investigation, click here
