| Full name: microfibril associated protein 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 4239 | HGNC ID: HGNC:7035 | Ensembl Gene: ENSG00000166482 | OMIM ID: 600596 |
| Drug and gene relationship at DGIdb | |||
Expression of MFAP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFAP4 | 4239 | 212713_at | -2.0163 | 0.0985 | |
| GSE20347 | MFAP4 | 4239 | 212713_at | -0.1880 | 0.2828 | |
| GSE23400 | MFAP4 | 4239 | 212713_at | -0.8470 | 0.0000 | |
| GSE26886 | MFAP4 | 4239 | 212713_at | 0.3955 | 0.2455 | |
| GSE29001 | MFAP4 | 4239 | 212713_at | -0.0924 | 0.7340 | |
| GSE38129 | MFAP4 | 4239 | 212713_at | -0.7850 | 0.0465 | |
| GSE45670 | MFAP4 | 4239 | 212713_at | -2.2530 | 0.0000 | |
| GSE53622 | MFAP4 | 4239 | 108905 | -1.9272 | 0.0000 | |
| GSE53624 | MFAP4 | 4239 | 108905 | -1.8406 | 0.0000 | |
| GSE63941 | MFAP4 | 4239 | 212713_at | -3.4113 | 0.0000 | |
| GSE77861 | MFAP4 | 4239 | 212713_at | 0.1524 | 0.3743 | |
| GSE97050 | MFAP4 | 4239 | A_23_P164057 | -1.5187 | 0.0786 | |
| SRP007169 | MFAP4 | 4239 | RNAseq | 0.1984 | 0.7099 | |
| SRP008496 | MFAP4 | 4239 | RNAseq | 0.7568 | 0.0518 | |
| SRP064894 | MFAP4 | 4239 | RNAseq | -0.9646 | 0.0432 | |
| SRP133303 | MFAP4 | 4239 | RNAseq | -1.8835 | 0.0000 | |
| SRP159526 | MFAP4 | 4239 | RNAseq | -1.1839 | 0.0009 | |
| SRP193095 | MFAP4 | 4239 | RNAseq | 0.2615 | 0.5296 | |
| SRP219564 | MFAP4 | 4239 | RNAseq | -0.2658 | 0.7876 | |
| TCGA | MFAP4 | 4239 | RNAseq | -0.7056 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by MFAP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFAP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFAP4 | 4239 | 4 | 3 | 23 | |
| GSE20123 | MFAP4 | 4239 | 4 | 4 | 22 | |
| GSE43470 | MFAP4 | 4239 | 1 | 5 | 37 | |
| GSE46452 | MFAP4 | 4239 | 34 | 1 | 24 | |
| GSE47630 | MFAP4 | 4239 | 7 | 1 | 32 | |
| GSE54993 | MFAP4 | 4239 | 3 | 3 | 64 | |
| GSE54994 | MFAP4 | 4239 | 6 | 6 | 41 | |
| GSE60625 | MFAP4 | 4239 | 4 | 0 | 7 | |
| GSE74703 | MFAP4 | 4239 | 1 | 2 | 33 | |
| GSE74704 | MFAP4 | 4239 | 3 | 1 | 16 | |
| TCGA | MFAP4 | 4239 | 19 | 24 | 53 |
Total number of gains: 86; Total number of losses: 50; Total Number of normals: 352.
Somatic mutations of MFAP4:
Generating mutation plots.
Highly correlated genes for MFAP4:
Showing top 20/1283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFAP4 | AFF3 | 0.884808 | 3 | 0 | 3 |
| MFAP4 | LINC01082 | 0.861383 | 5 | 0 | 5 |
| MFAP4 | CLEC3B | 0.859232 | 3 | 0 | 3 |
| MFAP4 | CYP21A2 | 0.85299 | 3 | 0 | 3 |
| MFAP4 | TCF21 | 0.836633 | 11 | 0 | 11 |
| MFAP4 | LINC01279 | 0.830682 | 4 | 0 | 4 |
| MFAP4 | PGM5-AS1 | 0.812431 | 3 | 0 | 3 |
| MFAP4 | PEG3 | 0.811234 | 6 | 0 | 6 |
| MFAP4 | KCNT2 | 0.809902 | 6 | 0 | 6 |
| MFAP4 | FIBIN | 0.808841 | 5 | 0 | 5 |
| MFAP4 | XKR4 | 0.808439 | 5 | 0 | 5 |
| MFAP4 | MRVI1 | 0.803945 | 8 | 0 | 8 |
| MFAP4 | ANGPTL1 | 0.80389 | 7 | 0 | 7 |
| MFAP4 | MAGI2-AS3 | 0.803604 | 6 | 0 | 6 |
| MFAP4 | AOC3 | 0.803323 | 12 | 0 | 12 |
| MFAP4 | IL6ST | 0.801194 | 8 | 0 | 8 |
| MFAP4 | NEGR1 | 0.798797 | 7 | 0 | 7 |
| MFAP4 | SYNPO2 | 0.798305 | 7 | 0 | 7 |
| MFAP4 | ASPA | 0.796793 | 10 | 0 | 9 |
| MFAP4 | ABCA8 | 0.790843 | 10 | 0 | 9 |
For details and further investigation, click here
