| Full name: ABI family member 3 binding protein | Alias Symbol: NESHBP|DKFZP586L2024|TARSH | ||
| Type: protein-coding gene | Cytoband: 3q12.2 | ||
| Entrez ID: 25890 | HGNC ID: HGNC:17265 | Ensembl Gene: ENSG00000154175 | OMIM ID: 606279 |
| Drug and gene relationship at DGIdb | |||
Expression of ABI3BP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABI3BP | 25890 | 223395_at | -1.9541 | 0.1283 | |
| GSE20347 | ABI3BP | 25890 | 220518_at | -0.2927 | 0.0059 | |
| GSE23400 | ABI3BP | 25890 | 220518_at | -0.3219 | 0.0000 | |
| GSE26886 | ABI3BP | 25890 | 223395_at | -0.2397 | 0.7461 | |
| GSE29001 | ABI3BP | 25890 | 220518_at | -0.6955 | 0.0008 | |
| GSE38129 | ABI3BP | 25890 | 220518_at | -0.7061 | 0.0000 | |
| GSE45670 | ABI3BP | 25890 | 223395_at | -4.1716 | 0.0000 | |
| GSE53622 | ABI3BP | 25890 | 60608 | -2.3587 | 0.0000 | |
| GSE53624 | ABI3BP | 25890 | 60608 | -2.3079 | 0.0000 | |
| GSE63941 | ABI3BP | 25890 | 223395_at | -2.4124 | 0.0679 | |
| GSE77861 | ABI3BP | 25890 | 223395_at | -0.3378 | 0.1208 | |
| GSE97050 | ABI3BP | 25890 | A_33_P3411975 | -0.8003 | 0.2789 | |
| SRP007169 | ABI3BP | 25890 | RNAseq | 0.5150 | 0.2653 | |
| SRP064894 | ABI3BP | 25890 | RNAseq | -0.1860 | 0.7374 | |
| SRP133303 | ABI3BP | 25890 | RNAseq | -1.4606 | 0.0021 | |
| SRP159526 | ABI3BP | 25890 | RNAseq | -1.2376 | 0.0328 | |
| SRP193095 | ABI3BP | 25890 | RNAseq | -0.4125 | 0.1702 | |
| SRP219564 | ABI3BP | 25890 | RNAseq | 0.1688 | 0.8746 | |
| TCGA | ABI3BP | 25890 | RNAseq | -1.2231 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ABI3BP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABI3BP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABI3BP | 25890 | 17 | 1 | 12 | |
| GSE20123 | ABI3BP | 25890 | 16 | 1 | 13 | |
| GSE43470 | ABI3BP | 25890 | 19 | 1 | 23 | |
| GSE46452 | ABI3BP | 25890 | 12 | 6 | 41 | |
| GSE47630 | ABI3BP | 25890 | 16 | 6 | 18 | |
| GSE54993 | ABI3BP | 25890 | 2 | 5 | 63 | |
| GSE54994 | ABI3BP | 25890 | 27 | 5 | 21 | |
| GSE60625 | ABI3BP | 25890 | 0 | 6 | 5 | |
| GSE74703 | ABI3BP | 25890 | 15 | 1 | 20 | |
| GSE74704 | ABI3BP | 25890 | 13 | 1 | 6 | |
| TCGA | ABI3BP | 25890 | 48 | 10 | 38 |
Total number of gains: 185; Total number of losses: 43; Total Number of normals: 260.
Somatic mutations of ABI3BP:
Generating mutation plots.
Highly correlated genes for ABI3BP:
Showing top 20/1308 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABI3BP | CLEC3B | 0.845976 | 3 | 0 | 3 |
| ABI3BP | CYP21A2 | 0.839073 | 3 | 0 | 3 |
| ABI3BP | SMOC2 | 0.822845 | 5 | 0 | 5 |
| ABI3BP | MRVI1 | 0.811393 | 6 | 0 | 6 |
| ABI3BP | SORCS1 | 0.801219 | 4 | 0 | 4 |
| ABI3BP | SYNPO2 | 0.793007 | 7 | 0 | 7 |
| ABI3BP | LINC01279 | 0.790749 | 4 | 0 | 4 |
| ABI3BP | SLITRK3 | 0.786739 | 7 | 0 | 7 |
| ABI3BP | SMTNL2 | 0.768808 | 5 | 0 | 5 |
| ABI3BP | XKR4 | 0.767959 | 6 | 0 | 6 |
| ABI3BP | ADAMTS9-AS2 | 0.767637 | 4 | 0 | 4 |
| ABI3BP | MAGI2-AS3 | 0.767204 | 5 | 0 | 5 |
| ABI3BP | C3orf70 | 0.765334 | 5 | 0 | 5 |
| ABI3BP | UTRN | 0.757451 | 6 | 0 | 6 |
| ABI3BP | PI16 | 0.756546 | 5 | 0 | 5 |
| ABI3BP | FRMD3 | 0.7543 | 5 | 0 | 5 |
| ABI3BP | PARD3B | 0.75304 | 6 | 0 | 6 |
| ABI3BP | BOC | 0.751213 | 6 | 0 | 6 |
| ABI3BP | LRFN5 | 0.750862 | 5 | 0 | 5 |
| ABI3BP | VAMP1 | 0.745757 | 4 | 0 | 4 |
For details and further investigation, click here
