| Full name: GRB10 interacting GYF protein 1 | Alias Symbol: GYF1 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 64599 | HGNC ID: HGNC:9126 | Ensembl Gene: ENSG00000146830 | OMIM ID: 612064 |
| Drug and gene relationship at DGIdb | |||
Expression of GIGYF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GIGYF1 | 64599 | 226768_at | 0.1898 | 0.3287 | |
| GSE26886 | GIGYF1 | 64599 | 226768_at | 0.3934 | 0.0032 | |
| GSE45670 | GIGYF1 | 64599 | 228755_at | 0.2322 | 0.1080 | |
| GSE53622 | GIGYF1 | 64599 | 46141 | 0.1182 | 0.2149 | |
| GSE53624 | GIGYF1 | 64599 | 46141 | 0.1262 | 0.0685 | |
| GSE63941 | GIGYF1 | 64599 | 226768_at | 1.0415 | 0.0001 | |
| GSE77861 | GIGYF1 | 64599 | 226768_at | 0.1163 | 0.5480 | |
| GSE97050 | GIGYF1 | 64599 | A_24_P231173 | 0.1361 | 0.5752 | |
| SRP007169 | GIGYF1 | 64599 | RNAseq | -0.0349 | 0.9291 | |
| SRP008496 | GIGYF1 | 64599 | RNAseq | 0.1581 | 0.5839 | |
| SRP064894 | GIGYF1 | 64599 | RNAseq | 0.3923 | 0.0180 | |
| SRP133303 | GIGYF1 | 64599 | RNAseq | 0.0227 | 0.8889 | |
| SRP159526 | GIGYF1 | 64599 | RNAseq | 0.3253 | 0.3596 | |
| SRP193095 | GIGYF1 | 64599 | RNAseq | 0.7979 | 0.0000 | |
| SRP219564 | GIGYF1 | 64599 | RNAseq | 0.6440 | 0.1529 | |
| TCGA | GIGYF1 | 64599 | RNAseq | -0.0279 | 0.5943 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GIGYF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GIGYF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GIGYF1 | 64599 | 13 | 0 | 17 | |
| GSE20123 | GIGYF1 | 64599 | 13 | 0 | 17 | |
| GSE43470 | GIGYF1 | 64599 | 7 | 2 | 34 | |
| GSE46452 | GIGYF1 | 64599 | 11 | 1 | 47 | |
| GSE47630 | GIGYF1 | 64599 | 7 | 3 | 30 | |
| GSE54993 | GIGYF1 | 64599 | 1 | 9 | 60 | |
| GSE54994 | GIGYF1 | 64599 | 16 | 3 | 34 | |
| GSE60625 | GIGYF1 | 64599 | 0 | 0 | 11 | |
| GSE74703 | GIGYF1 | 64599 | 7 | 1 | 28 | |
| GSE74704 | GIGYF1 | 64599 | 9 | 0 | 11 | |
| TCGA | GIGYF1 | 64599 | 53 | 6 | 37 |
Total number of gains: 137; Total number of losses: 25; Total Number of normals: 326.
Somatic mutations of GIGYF1:
Generating mutation plots.
Highly correlated genes for GIGYF1:
Showing top 20/568 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GIGYF1 | ZNF747 | 0.776764 | 3 | 0 | 3 |
| GIGYF1 | CLIP2 | 0.747596 | 3 | 0 | 3 |
| GIGYF1 | HNRNPC | 0.741768 | 3 | 0 | 3 |
| GIGYF1 | LINC00642 | 0.741568 | 3 | 0 | 3 |
| GIGYF1 | PTGES2 | 0.738051 | 3 | 0 | 3 |
| GIGYF1 | MAP3K13 | 0.730873 | 4 | 0 | 4 |
| GIGYF1 | SLC25A35 | 0.724424 | 3 | 0 | 3 |
| GIGYF1 | FN3K | 0.716758 | 3 | 0 | 3 |
| GIGYF1 | IL17C | 0.716401 | 4 | 0 | 4 |
| GIGYF1 | SH3BP1 | 0.714248 | 4 | 0 | 4 |
| GIGYF1 | PHF5A | 0.712948 | 3 | 0 | 3 |
| GIGYF1 | SORBS3 | 0.705366 | 4 | 0 | 4 |
| GIGYF1 | WDHD1 | 0.701855 | 3 | 0 | 3 |
| GIGYF1 | SNAPC1 | 0.701223 | 3 | 0 | 3 |
| GIGYF1 | PANK4 | 0.70012 | 3 | 0 | 3 |
| GIGYF1 | STIP1 | 0.699101 | 3 | 0 | 3 |
| GIGYF1 | DEDD | 0.696958 | 4 | 0 | 4 |
| GIGYF1 | EPX | 0.694376 | 3 | 0 | 3 |
| GIGYF1 | NIT1 | 0.693138 | 3 | 0 | 3 |
| GIGYF1 | VAMP2 | 0.691262 | 4 | 0 | 4 |
For details and further investigation, click here
