C11orf24

 

Full name: chromosome 11 open reading frame 24 Alias Symbol: DM4E3
Type: protein-coding gene Cytoband: 11q13.2
Entrez ID: 53838 HGNC ID: HGNC:1174 Ensembl Gene: ENSG00000171067 OMIM ID: 610880
Drug and gene relationship at DGIdb

 

Expression of C11orf24:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C11orf24 53838 52164_at 0.6926 0.0924
GSE20347 C11orf24 53838 52164_at 1.1469 0.0000
GSE23400 C11orf24 53838 52164_at 0.7547 0.0000
GSE26886 C11orf24 53838 52164_at 1.9543 0.0000
GSE29001 C11orf24 53838 52164_at 0.8949 0.0002
GSE38129 C11orf24 53838 52164_at 0.8625 0.0000
GSE45670 C11orf24 53838 52164_at 0.6428 0.0125
GSE53622 C11orf24 53838 39679 0.9921 0.0000
GSE53624 C11orf24 53838 39679 1.3937 0.0000
GSE63941 C11orf24 53838 52164_at -1.4867 0.0269
GSE77861 C11orf24 53838 52164_at 0.9547 0.0005
GSE97050 C11orf24 53838 A_23_P12911 1.0370 0.1581
SRP007169 C11orf24 53838 RNAseq 2.4987 0.0000
SRP008496 C11orf24 53838 RNAseq 1.7335 0.0000
SRP064894 C11orf24 53838 RNAseq 0.8937 0.0017
SRP133303 C11orf24 53838 RNAseq 1.1883 0.0000
SRP159526 C11orf24 53838 RNAseq 1.2524 0.0031
SRP193095 C11orf24 53838 RNAseq 0.8041 0.0032
SRP219564 C11orf24 53838 RNAseq 0.9390 0.0589
TCGA C11orf24 53838 RNAseq 0.0977 0.1714

Upregulated datasets: 7; Downregulated datasets: 1.  


 

Survival by C11orf24 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C11orf24:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C11orf24 53838 10 3 17
GSE20123 C11orf24 53838 10 3 17
GSE43470 C11orf24 53838 4 3 36
GSE46452 C11orf24 53838 17 3 39
GSE47630 C11orf24 53838 12 3 25
GSE54993 C11orf24 53838 2 3 65
GSE54994 C11orf24 53838 14 4 35
GSE60625 C11orf24 53838 0 3 8
GSE74703 C11orf24 53838 3 2 31
GSE74704 C11orf24 53838 8 1 11
TCGA C11orf24 53838 36 8 52

Total number of gains: 116; Total number of losses: 36; Total Number of normals: 336.  


 

Somatic mutations of C11orf24:

 

Generating mutation plots.

 

Highly correlated genes for C11orf24:

 

Showing top 20/1855 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C11orf24FMNL20.827939707
C11orf24BOLA30.79643707
C11orf24PDIA50.796232303
C11orf24LPCAT10.78455411011
C11orf24FADS10.777933303
C11orf24WDR540.777896707
C11orf24A4GALT0.776636303
C11orf24LRRC8C0.775401303
C11orf24SLC25A320.77202712011
C11orf24GLIS30.768118505
C11orf24ARPC1B0.76500411011
C11orf24SPON20.760466303
C11orf24ZNF4690.759918707
C11orf24SLC35B20.757508303
C11orf24FAM89A0.756348303
C11orf24NGF0.747717303
C11orf24STRIP20.74458606
C11orf24MMP10.744112012
C11orf24FCGR3A0.741956303
C11orf24SLC39A140.74182411010

For details and further investigation, click here