CMC2

 

Full name: C-X9-C motif containing 2 Alias Symbol: DC13|MGC45036
Type: protein-coding gene Cytoband: 16q23.2
Entrez ID: 56942 HGNC ID: HGNC:24447 Ensembl Gene: ENSG00000103121 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CMC2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CMC2 56942 218447_at 0.5854 0.1166
GSE20347 CMC2 56942 218447_at 0.9266 0.0000
GSE23400 CMC2 56942 218447_at 0.7880 0.0000
GSE26886 CMC2 56942 218447_at 1.2497 0.0000
GSE29001 CMC2 56942 218447_at 0.9055 0.0037
GSE38129 CMC2 56942 218447_at 0.9440 0.0000
GSE45670 CMC2 56942 218447_at 0.6182 0.0002
GSE53622 CMC2 56942 96825 0.7138 0.0000
GSE53624 CMC2 56942 27125 0.9915 0.0000
GSE63941 CMC2 56942 218447_at 0.3761 0.3261
GSE77861 CMC2 56942 218447_at 0.8829 0.0023
SRP007169 CMC2 56942 RNAseq 1.4270 0.0023
SRP008496 CMC2 56942 RNAseq 1.0501 0.0030
SRP064894 CMC2 56942 RNAseq 0.6107 0.0035
SRP133303 CMC2 56942 RNAseq 0.6396 0.0000
SRP159526 CMC2 56942 RNAseq 1.1261 0.0218
SRP193095 CMC2 56942 RNAseq 0.4038 0.0002
SRP219564 CMC2 56942 RNAseq 0.1875 0.5939

Upregulated datasets: 4; Downregulated datasets: 0.  

 

Survival by CMC2 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of CMC2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CMC2 56942 5 2 23
GSE20123 CMC2 56942 5 2 23
GSE43470 CMC2 56942 2 8 33
GSE46452 CMC2 56942 37 2 20
GSE47630 CMC2 56942 11 8 21
GSE54993 CMC2 56942 2 4 64
GSE54994 CMC2 56942 7 10 36
GSE60625 CMC2 56942 4 0 7
GSE74703 CMC2 56942 2 6 28
GSE74704 CMC2 56942 3 2 15
TCGA CMC2 56942 24 16 56

Total number of gains: 102; Total number of losses: 60; Total Number of normals: 326.  

 

Somatic mutations of CMC2:

 

Generating mutation plots.

 

Highly correlated genes for CMC2:

 

Showing top 20/1828 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CMC2PFDN20.77266510010
CMC2CMSS10.759571606
CMC2MRPL470.757608606
CMC2EMC80.75687911011
CMC2CKS1B0.75231810010
CMC2CTU20.739582606
CMC2NTMT10.737309707
CMC2SLC25A320.73033210010
CMC2DNAJC20.72802410010
CMC2ZNF3170.727972303
CMC2ATP6V1C10.72581909
CMC2HSPD10.72464911010
CMC2HTRA30.720365303
CMC2CBX30.71908410010
CMC2CENPN0.71680611010
CMC2PSMB20.71154710010
CMC2RUVBL10.71090510010
CMC2GMNN0.71035310010
CMC2PSMB40.709353909
CMC2TMEM184B0.708898909

For details and further investigation, click here