| Full name: C-type lectin domain family 12 member A | Alias Symbol: CLL-1|MICL|CD371|DCAL-2 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 160364 | HGNC ID: HGNC:31713 | Ensembl Gene: ENSG00000172322 | OMIM ID: 612088 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC12A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC12A | 160364 | 1552398_a_at | 0.4320 | 0.5061 | |
| GSE26886 | CLEC12A | 160364 | 1569401_at | 0.1901 | 0.3621 | |
| GSE45670 | CLEC12A | 160364 | 1552398_a_at | 0.4406 | 0.2804 | |
| GSE53622 | CLEC12A | 160364 | 63196 | 0.6797 | 0.0094 | |
| GSE53624 | CLEC12A | 160364 | 63196 | 1.0156 | 0.0002 | |
| GSE63941 | CLEC12A | 160364 | 1552398_a_at | 0.5718 | 0.3985 | |
| GSE77861 | CLEC12A | 160364 | 1569401_at | -0.0173 | 0.8705 | |
| GSE97050 | CLEC12A | 160364 | A_23_P128470 | 0.9382 | 0.1836 | |
| SRP064894 | CLEC12A | 160364 | RNAseq | 0.6434 | 0.1621 | |
| SRP133303 | CLEC12A | 160364 | RNAseq | 0.7944 | 0.0494 | |
| SRP159526 | CLEC12A | 160364 | RNAseq | 2.4875 | 0.0009 | |
| SRP193095 | CLEC12A | 160364 | RNAseq | 1.1661 | 0.0000 | |
| SRP219564 | CLEC12A | 160364 | RNAseq | 1.0399 | 0.0861 | |
| TCGA | CLEC12A | 160364 | RNAseq | 1.2850 | 0.0007 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by CLEC12A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC12A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC12A | 160364 | 5 | 3 | 22 | |
| GSE20123 | CLEC12A | 160364 | 5 | 3 | 22 | |
| GSE43470 | CLEC12A | 160364 | 8 | 3 | 32 | |
| GSE46452 | CLEC12A | 160364 | 10 | 1 | 48 | |
| GSE47630 | CLEC12A | 160364 | 14 | 2 | 24 | |
| GSE54993 | CLEC12A | 160364 | 1 | 10 | 59 | |
| GSE54994 | CLEC12A | 160364 | 9 | 2 | 42 | |
| GSE60625 | CLEC12A | 160364 | 0 | 1 | 10 | |
| GSE74703 | CLEC12A | 160364 | 8 | 2 | 26 | |
| GSE74704 | CLEC12A | 160364 | 3 | 2 | 15 | |
| TCGA | CLEC12A | 160364 | 40 | 6 | 50 |
Total number of gains: 103; Total number of losses: 35; Total Number of normals: 350.
Somatic mutations of CLEC12A:
Generating mutation plots.
Highly correlated genes for CLEC12A:
Showing top 20/401 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC12A | C19orf38 | 0.779613 | 3 | 0 | 3 |
| CLEC12A | RGS18 | 0.77313 | 4 | 0 | 4 |
| CLEC12A | MRPS35 | 0.768708 | 3 | 0 | 3 |
| CLEC12A | SND1 | 0.766795 | 3 | 0 | 3 |
| CLEC12A | SDHAF2 | 0.74886 | 3 | 0 | 3 |
| CLEC12A | CD86 | 0.743045 | 3 | 0 | 3 |
| CLEC12A | TTI2 | 0.741803 | 3 | 0 | 3 |
| CLEC12A | SLC25A11 | 0.736817 | 3 | 0 | 3 |
| CLEC12A | HCLS1 | 0.731069 | 4 | 0 | 4 |
| CLEC12A | SAMM50 | 0.728463 | 3 | 0 | 3 |
| CLEC12A | CCL18 | 0.724707 | 4 | 0 | 4 |
| CLEC12A | CERKL | 0.723326 | 3 | 0 | 3 |
| CLEC12A | AKR1B1 | 0.720952 | 3 | 0 | 3 |
| CLEC12A | GPR34 | 0.717774 | 4 | 0 | 4 |
| CLEC12A | MNDA | 0.71637 | 4 | 0 | 4 |
| CLEC12A | SUCNR1 | 0.714903 | 4 | 0 | 4 |
| CLEC12A | PILRA | 0.713083 | 4 | 0 | 4 |
| CLEC12A | CBFB | 0.70907 | 3 | 0 | 3 |
| CLEC12A | MS4A4A | 0.708895 | 5 | 0 | 5 |
| CLEC12A | TMC7 | 0.708801 | 3 | 0 | 3 |
For details and further investigation, click here
