PSRC1

 

Full name: proline and serine rich coiled-coil 1 Alias Symbol: DDA3
Type: protein-coding gene Cytoband: 1p13.3
Entrez ID: 84722 HGNC ID: HGNC:24472 Ensembl Gene: ENSG00000134222 OMIM ID: 613126
Drug and gene relationship at DGIdb

 

Expression of PSRC1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PSRC1 84722 201896_s_at 0.3069 0.4328
GSE20347 PSRC1 84722 201896_s_at 1.0128 0.0000
GSE23400 PSRC1 84722 201896_s_at 0.3957 0.0000
GSE26886 PSRC1 84722 201896_s_at 0.1158 0.6811
GSE29001 PSRC1 84722 201896_s_at 0.7496 0.0007
GSE38129 PSRC1 84722 201896_s_at 1.0334 0.0000
GSE45670 PSRC1 84722 201896_s_at 0.4426 0.1356
GSE53622 PSRC1 84722 57757 0.7732 0.0000
GSE53624 PSRC1 84722 57757 1.1451 0.0000
GSE63941 PSRC1 84722 201896_s_at 1.8373 0.0364
GSE77861 PSRC1 84722 201896_s_at 0.4658 0.0914
GSE97050 PSRC1 84722 A_23_P46539 0.3852 0.1942
SRP007169 PSRC1 84722 RNAseq 1.4791 0.0077
SRP064894 PSRC1 84722 RNAseq 1.2348 0.0001
SRP133303 PSRC1 84722 RNAseq 0.6954 0.0024
SRP159526 PSRC1 84722 RNAseq 0.8837 0.1813
SRP193095 PSRC1 84722 RNAseq 0.9405 0.0000
SRP219564 PSRC1 84722 RNAseq -0.0851 0.8365
TCGA PSRC1 84722 RNAseq 0.7401 0.0000

Upregulated datasets: 6; Downregulated datasets: 0.  

 

Survival by PSRC1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PSRC1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PSRC1 84722 0 12 18
GSE20123 PSRC1 84722 0 11 19
GSE43470 PSRC1 84722 0 8 35
GSE46452 PSRC1 84722 2 1 56
GSE47630 PSRC1 84722 9 5 26
GSE54993 PSRC1 84722 0 1 69
GSE54994 PSRC1 84722 7 4 42
GSE60625 PSRC1 84722 0 0 11
GSE74703 PSRC1 84722 0 6 30
GSE74704 PSRC1 84722 0 7 13
TCGA PSRC1 84722 9 26 61

Total number of gains: 27; Total number of losses: 81; Total Number of normals: 380.  

 

Somatic mutations of PSRC1:

 

Generating mutation plots.

 

Highly correlated genes for PSRC1:

 

Showing top 20/745 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PSRC1NCAPH0.715865909
PSRC1EXO10.67497212012
PSRC1AURKB0.67384913012
PSRC1KIF4A0.67209813011
PSRC1TOP2A0.66821811010
PSRC1RFC40.66444912011
PSRC1CDC200.66402713012
PSRC1NEK20.66022812010
PSRC1WDR540.659163505
PSRC1IFITM10.658959403
PSRC1PLA2G150.658265504
PSRC1UBE2C0.6552112010
PSRC1NUSAP10.65487512010
PSRC1ANP32E0.654203909
PSRC1BUB1B0.6540171109
PSRC1CBX30.6533821009
PSRC1SPC240.652711706
PSRC1MCM20.65156612011
PSRC1MSH20.6508541008
PSRC1CCT70.650568907

For details and further investigation, click here