| Full name: sperm associated antigen 11A | Alias Symbol: HE2|EDDM2A | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 653423 | HGNC ID: HGNC:33342 | Ensembl Gene: ENSG00000178287 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SPAG11A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPAG11A | 653423 | 210884_s_at | -0.0759 | 0.7156 | |
| GSE20347 | SPAG11A | 653423 | 210884_s_at | -0.1126 | 0.1508 | |
| GSE23400 | SPAG11A | 653423 | 210884_s_at | -0.0579 | 0.0518 | |
| GSE26886 | SPAG11A | 653423 | 210884_s_at | -0.2604 | 0.1441 | |
| GSE29001 | SPAG11A | 653423 | 210884_s_at | -0.2230 | 0.1109 | |
| GSE38129 | SPAG11A | 653423 | 210884_s_at | -0.1549 | 0.0773 | |
| GSE45670 | SPAG11A | 653423 | 210884_s_at | 0.0849 | 0.3660 | |
| GSE63941 | SPAG11A | 653423 | 210884_s_at | 0.0605 | 0.6545 | |
| GSE77861 | SPAG11A | 653423 | 210884_s_at | -0.2727 | 0.0652 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SPAG11A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SPAG11A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPAG11A | 653423 | 4 | 10 | 16 | |
| GSE20123 | SPAG11A | 653423 | 4 | 10 | 16 | |
| GSE43470 | SPAG11A | 653423 | 4 | 10 | 29 | |
| GSE46452 | SPAG11A | 653423 | 12 | 14 | 33 | |
| GSE47630 | SPAG11A | 653423 | 8 | 10 | 22 | |
| GSE54993 | SPAG11A | 653423 | 3 | 14 | 53 | |
| GSE54994 | SPAG11A | 653423 | 10 | 19 | 24 | |
| GSE60625 | SPAG11A | 653423 | 3 | 0 | 8 | |
| GSE74703 | SPAG11A | 653423 | 4 | 8 | 24 | |
| GSE74704 | SPAG11A | 653423 | 3 | 7 | 10 | |
| TCGA | SPAG11A | 653423 | 13 | 40 | 43 |
Total number of gains: 68; Total number of losses: 142; Total Number of normals: 278.
Somatic mutations of SPAG11A:
Generating mutation plots.
Highly correlated genes for SPAG11A:
Showing top 20/876 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPAG11A | BPIFA2 | 0.715013 | 3 | 0 | 3 |
| SPAG11A | IGF2-AS | 0.70464 | 4 | 0 | 4 |
| SPAG11A | KCNJ4 | 0.701499 | 3 | 0 | 3 |
| SPAG11A | CD79B | 0.698368 | 3 | 0 | 3 |
| SPAG11A | PROP1 | 0.691378 | 5 | 0 | 5 |
| SPAG11A | NEURL1 | 0.688694 | 6 | 0 | 5 |
| SPAG11A | HLA-DOA | 0.681194 | 6 | 0 | 5 |
| SPAG11A | ST8SIA3 | 0.679053 | 3 | 0 | 3 |
| SPAG11A | ZNF460 | 0.678653 | 4 | 0 | 3 |
| SPAG11A | THRB | 0.678297 | 3 | 0 | 3 |
| SPAG11A | PRKAR2A | 0.676696 | 4 | 0 | 4 |
| SPAG11A | CYP2A6 | 0.673626 | 6 | 0 | 5 |
| SPAG11A | SLC25A47 | 0.673409 | 3 | 0 | 3 |
| SPAG11A | SLC45A2 | 0.673086 | 4 | 0 | 4 |
| SPAG11A | PHF7 | 0.672059 | 6 | 0 | 6 |
| SPAG11A | TCL1A | 0.669484 | 3 | 0 | 3 |
| SPAG11A | CLDN2 | 0.668009 | 3 | 0 | 3 |
| SPAG11A | PIK3R5 | 0.663022 | 5 | 0 | 5 |
| SPAG11A | CIITA | 0.661189 | 4 | 0 | 4 |
| SPAG11A | KCNQ1DN | 0.660585 | 4 | 0 | 4 |
For details and further investigation, click here
