| Full name: cysteine rich hydrophobic domain 2 | Alias Symbol: BTL | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 26511 | HGNC ID: HGNC:1935 | Ensembl Gene: ENSG00000109220 | OMIM ID: 604332 |
| Drug and gene relationship at DGIdb | |||
Expression of CHIC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHIC2 | 26511 | 219492_at | -0.3430 | 0.3244 | |
| GSE20347 | CHIC2 | 26511 | 219492_at | -1.0478 | 0.0000 | |
| GSE23400 | CHIC2 | 26511 | 219492_at | -0.5434 | 0.0000 | |
| GSE26886 | CHIC2 | 26511 | 219492_at | -1.8219 | 0.0000 | |
| GSE29001 | CHIC2 | 26511 | 219492_at | -0.8040 | 0.0006 | |
| GSE38129 | CHIC2 | 26511 | 219492_at | -0.3475 | 0.1721 | |
| GSE45670 | CHIC2 | 26511 | 219492_at | -0.0946 | 0.7957 | |
| GSE53622 | CHIC2 | 26511 | 13070 | -0.5787 | 0.0000 | |
| GSE53624 | CHIC2 | 26511 | 13070 | -0.6018 | 0.0000 | |
| GSE63941 | CHIC2 | 26511 | 219492_at | -0.6213 | 0.2313 | |
| GSE77861 | CHIC2 | 26511 | 219492_at | -0.8449 | 0.0374 | |
| GSE97050 | CHIC2 | 26511 | A_23_P110345 | -0.1975 | 0.4581 | |
| SRP007169 | CHIC2 | 26511 | RNAseq | -1.7810 | 0.0004 | |
| SRP008496 | CHIC2 | 26511 | RNAseq | -1.5624 | 0.0000 | |
| SRP064894 | CHIC2 | 26511 | RNAseq | -0.5927 | 0.0009 | |
| SRP133303 | CHIC2 | 26511 | RNAseq | -0.3951 | 0.0154 | |
| SRP159526 | CHIC2 | 26511 | RNAseq | -0.6381 | 0.0028 | |
| SRP193095 | CHIC2 | 26511 | RNAseq | -0.7548 | 0.0000 | |
| SRP219564 | CHIC2 | 26511 | RNAseq | -0.8534 | 0.0393 | |
| TCGA | CHIC2 | 26511 | RNAseq | 0.2392 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by CHIC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHIC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHIC2 | 26511 | 3 | 11 | 16 | |
| GSE20123 | CHIC2 | 26511 | 2 | 11 | 17 | |
| GSE43470 | CHIC2 | 26511 | 0 | 14 | 29 | |
| GSE46452 | CHIC2 | 26511 | 1 | 36 | 22 | |
| GSE47630 | CHIC2 | 26511 | 1 | 18 | 21 | |
| GSE54993 | CHIC2 | 26511 | 7 | 0 | 63 | |
| GSE54994 | CHIC2 | 26511 | 2 | 10 | 41 | |
| GSE60625 | CHIC2 | 26511 | 0 | 0 | 11 | |
| GSE74703 | CHIC2 | 26511 | 0 | 12 | 24 | |
| GSE74704 | CHIC2 | 26511 | 1 | 6 | 13 | |
| TCGA | CHIC2 | 26511 | 19 | 26 | 51 |
Total number of gains: 36; Total number of losses: 144; Total Number of normals: 308.
Somatic mutations of CHIC2:
Generating mutation plots.
Highly correlated genes for CHIC2:
Showing top 20/1364 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHIC2 | SH3PXD2A-AS1 | 0.833664 | 3 | 0 | 3 |
| CHIC2 | SPAG17 | 0.829959 | 3 | 0 | 3 |
| CHIC2 | SFTA2 | 0.802829 | 3 | 0 | 3 |
| CHIC2 | RBM20 | 0.802633 | 3 | 0 | 3 |
| CHIC2 | C15orf48 | 0.785814 | 5 | 0 | 5 |
| CHIC2 | ZNRF1 | 0.785005 | 3 | 0 | 3 |
| CHIC2 | GGA3 | 0.778238 | 3 | 0 | 3 |
| CHIC2 | GRPEL2 | 0.766025 | 6 | 0 | 6 |
| CHIC2 | PSCA | 0.759055 | 6 | 0 | 6 |
| CHIC2 | TP53RK | 0.757728 | 3 | 0 | 3 |
| CHIC2 | ATP13A4 | 0.757061 | 5 | 0 | 5 |
| CHIC2 | TPRG1 | 0.754059 | 6 | 0 | 5 |
| CHIC2 | NAGK | 0.752408 | 10 | 0 | 9 |
| CHIC2 | FAM3D | 0.751226 | 5 | 0 | 5 |
| CHIC2 | SLC46A2 | 0.748441 | 6 | 0 | 6 |
| CHIC2 | SNORA68 | 0.747632 | 3 | 0 | 3 |
| CHIC2 | SCP2 | 0.746233 | 9 | 0 | 9 |
| CHIC2 | ULK3 | 0.743574 | 6 | 0 | 6 |
| CHIC2 | SAMD9L | 0.742425 | 3 | 0 | 3 |
| CHIC2 | RANBP9 | 0.741793 | 9 | 0 | 9 |
For details and further investigation, click here
