| Full name: ATPase family AAA domain containing 1 | Alias Symbol: FLJ14600 | ||
| Type: protein-coding gene | Cytoband: 10q23.31 | ||
| Entrez ID: 84896 | HGNC ID: HGNC:25903 | Ensembl Gene: ENSG00000138138 | OMIM ID: 614452 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ATAD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATAD1 | 84896 | 224850_at | -0.1969 | 0.5785 | |
| GSE26886 | ATAD1 | 84896 | 224850_at | -0.5531 | 0.0319 | |
| GSE45670 | ATAD1 | 84896 | 224850_at | -0.0911 | 0.4773 | |
| GSE53622 | ATAD1 | 84896 | 117201 | 0.0089 | 0.8853 | |
| GSE53624 | ATAD1 | 84896 | 117201 | 0.2600 | 0.0000 | |
| GSE63941 | ATAD1 | 84896 | 224850_at | -0.2868 | 0.4511 | |
| GSE77861 | ATAD1 | 84896 | 224850_at | 0.0335 | 0.9243 | |
| GSE97050 | ATAD1 | 84896 | A_23_P75288 | -0.0978 | 0.6740 | |
| SRP007169 | ATAD1 | 84896 | RNAseq | -0.2137 | 0.6973 | |
| SRP008496 | ATAD1 | 84896 | RNAseq | 0.0309 | 0.9188 | |
| SRP064894 | ATAD1 | 84896 | RNAseq | -0.1048 | 0.4893 | |
| SRP133303 | ATAD1 | 84896 | RNAseq | 0.3455 | 0.0053 | |
| SRP159526 | ATAD1 | 84896 | RNAseq | 0.0949 | 0.7612 | |
| SRP193095 | ATAD1 | 84896 | RNAseq | -0.1014 | 0.2049 | |
| SRP219564 | ATAD1 | 84896 | RNAseq | 0.0226 | 0.9226 | |
| TCGA | ATAD1 | 84896 | RNAseq | -0.0262 | 0.6018 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ATAD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATAD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATAD1 | 84896 | 2 | 7 | 21 | |
| GSE20123 | ATAD1 | 84896 | 2 | 6 | 22 | |
| GSE43470 | ATAD1 | 84896 | 0 | 9 | 34 | |
| GSE46452 | ATAD1 | 84896 | 0 | 11 | 48 | |
| GSE47630 | ATAD1 | 84896 | 2 | 14 | 24 | |
| GSE54993 | ATAD1 | 84896 | 7 | 0 | 63 | |
| GSE54994 | ATAD1 | 84896 | 1 | 11 | 41 | |
| GSE60625 | ATAD1 | 84896 | 0 | 0 | 11 | |
| GSE74703 | ATAD1 | 84896 | 0 | 7 | 29 | |
| GSE74704 | ATAD1 | 84896 | 1 | 4 | 15 | |
| TCGA | ATAD1 | 84896 | 6 | 29 | 61 |
Total number of gains: 21; Total number of losses: 98; Total Number of normals: 369.
Somatic mutations of ATAD1:
Generating mutation plots.
Highly correlated genes for ATAD1:
Showing top 20/245 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATAD1 | CGRRF1 | 0.759478 | 3 | 0 | 3 |
| ATAD1 | XK | 0.740286 | 3 | 0 | 3 |
| ATAD1 | COQ9 | 0.730267 | 3 | 0 | 3 |
| ATAD1 | PDCD7 | 0.729865 | 3 | 0 | 3 |
| ATAD1 | AP5M1 | 0.72732 | 3 | 0 | 3 |
| ATAD1 | PPM1A | 0.727164 | 3 | 0 | 3 |
| ATAD1 | MCMBP | 0.716129 | 3 | 0 | 3 |
| ATAD1 | SRSF7 | 0.711484 | 3 | 0 | 3 |
| ATAD1 | RPP30 | 0.709058 | 5 | 0 | 5 |
| ATAD1 | ATG14 | 0.706485 | 3 | 0 | 3 |
| ATAD1 | POLR2B | 0.69695 | 3 | 0 | 3 |
| ATAD1 | TOPORS | 0.691114 | 3 | 0 | 3 |
| ATAD1 | PRPF38A | 0.690872 | 3 | 0 | 3 |
| ATAD1 | APC | 0.684474 | 3 | 0 | 3 |
| ATAD1 | CUL2 | 0.684203 | 4 | 0 | 4 |
| ATAD1 | NFKB1 | 0.681632 | 3 | 0 | 3 |
| ATAD1 | ISOC1 | 0.676979 | 4 | 0 | 3 |
| ATAD1 | RWDD2B | 0.67002 | 3 | 0 | 3 |
| ATAD1 | UBR2 | 0.668135 | 3 | 0 | 3 |
| ATAD1 | LRRC40 | 0.66699 | 4 | 0 | 4 |
For details and further investigation, click here
