| Full name: zinc finger protein like 1 | Alias Symbol: D11S750|MCG4 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 7542 | HGNC ID: HGNC:12868 | Ensembl Gene: ENSG00000162300 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZFPL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFPL1 | 7542 | 209428_s_at | 0.0462 | 0.9243 | |
| GSE20347 | ZFPL1 | 7542 | 209428_s_at | -0.0171 | 0.8776 | |
| GSE23400 | ZFPL1 | 7542 | 209428_s_at | 0.0219 | 0.6458 | |
| GSE26886 | ZFPL1 | 7542 | 209428_s_at | -0.3555 | 0.1622 | |
| GSE29001 | ZFPL1 | 7542 | 209428_s_at | -0.0630 | 0.6981 | |
| GSE38129 | ZFPL1 | 7542 | 209428_s_at | 0.0783 | 0.3486 | |
| GSE45670 | ZFPL1 | 7542 | 214311_at | -0.0891 | 0.3644 | |
| GSE53622 | ZFPL1 | 7542 | 69510 | 0.1707 | 0.0256 | |
| GSE53624 | ZFPL1 | 7542 | 69510 | 0.2731 | 0.0022 | |
| GSE63941 | ZFPL1 | 7542 | 209428_s_at | 1.6791 | 0.0003 | |
| GSE77861 | ZFPL1 | 7542 | 209428_s_at | 0.0934 | 0.5539 | |
| GSE97050 | ZFPL1 | 7542 | A_23_P98232 | 0.3616 | 0.3781 | |
| SRP007169 | ZFPL1 | 7542 | RNAseq | -0.6373 | 0.0681 | |
| SRP008496 | ZFPL1 | 7542 | RNAseq | -0.7004 | 0.0035 | |
| SRP064894 | ZFPL1 | 7542 | RNAseq | 0.4298 | 0.1301 | |
| SRP133303 | ZFPL1 | 7542 | RNAseq | 0.3646 | 0.0645 | |
| SRP159526 | ZFPL1 | 7542 | RNAseq | 0.1124 | 0.6758 | |
| SRP193095 | ZFPL1 | 7542 | RNAseq | 0.1527 | 0.1065 | |
| SRP219564 | ZFPL1 | 7542 | RNAseq | 0.2361 | 0.5538 | |
| TCGA | ZFPL1 | 7542 | RNAseq | 0.0944 | 0.0823 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZFPL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZFPL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFPL1 | 7542 | 7 | 6 | 17 | |
| GSE20123 | ZFPL1 | 7542 | 7 | 6 | 17 | |
| GSE43470 | ZFPL1 | 7542 | 2 | 3 | 38 | |
| GSE46452 | ZFPL1 | 7542 | 10 | 4 | 45 | |
| GSE47630 | ZFPL1 | 7542 | 5 | 6 | 29 | |
| GSE54993 | ZFPL1 | 7542 | 3 | 0 | 67 | |
| GSE54994 | ZFPL1 | 7542 | 6 | 5 | 42 | |
| GSE60625 | ZFPL1 | 7542 | 0 | 3 | 8 | |
| GSE74703 | ZFPL1 | 7542 | 2 | 1 | 33 | |
| GSE74704 | ZFPL1 | 7542 | 5 | 4 | 11 | |
| TCGA | ZFPL1 | 7542 | 23 | 7 | 66 |
Total number of gains: 70; Total number of losses: 45; Total Number of normals: 373.
Somatic mutations of ZFPL1:
Generating mutation plots.
Highly correlated genes for ZFPL1:
Showing top 20/505 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFPL1 | GMCL1 | 0.808019 | 3 | 0 | 3 |
| ZFPL1 | LSM4 | 0.794188 | 3 | 0 | 3 |
| ZFPL1 | RAC1 | 0.788842 | 3 | 0 | 3 |
| ZFPL1 | SRSF7 | 0.783763 | 3 | 0 | 3 |
| ZFPL1 | MKRN1 | 0.758642 | 3 | 0 | 3 |
| ZFPL1 | UBA1 | 0.744835 | 4 | 0 | 4 |
| ZFPL1 | LSM10 | 0.744347 | 4 | 0 | 4 |
| ZFPL1 | SLC38A1 | 0.742252 | 3 | 0 | 3 |
| ZFPL1 | CNOT10 | 0.742006 | 3 | 0 | 3 |
| ZFPL1 | TMEM216 | 0.740825 | 3 | 0 | 3 |
| ZFPL1 | TRMT2B | 0.740398 | 3 | 0 | 3 |
| ZFPL1 | MTFMT | 0.737441 | 3 | 0 | 3 |
| ZFPL1 | LMBR1 | 0.733308 | 4 | 0 | 4 |
| ZFPL1 | PCBP2 | 0.729677 | 3 | 0 | 3 |
| ZFPL1 | EXOC3L2 | 0.727217 | 3 | 0 | 3 |
| ZFPL1 | TM4SF18 | 0.725403 | 3 | 0 | 3 |
| ZFPL1 | RAB4B | 0.724969 | 4 | 0 | 4 |
| ZFPL1 | TCEANC2 | 0.724824 | 3 | 0 | 3 |
| ZFPL1 | WDR77 | 0.724097 | 4 | 0 | 3 |
| ZFPL1 | MRPL37 | 0.720608 | 5 | 0 | 5 |
For details and further investigation, click here
