| Full name: splicing factor proline and glutamine rich | Alias Symbol: PSF|PPP1R140 | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 6421 | HGNC ID: HGNC:10774 | Ensembl Gene: ENSG00000116560 | OMIM ID: 605199 |
| Drug and gene relationship at DGIdb | |||
Expression of SFPQ:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFPQ | 6421 | 201586_s_at | 0.3398 | 0.3905 | |
| GSE20347 | SFPQ | 6421 | 201586_s_at | 0.4293 | 0.0003 | |
| GSE23400 | SFPQ | 6421 | 201586_s_at | 0.5102 | 0.0000 | |
| GSE26886 | SFPQ | 6421 | 201586_s_at | -0.6551 | 0.0009 | |
| GSE29001 | SFPQ | 6421 | 214016_s_at | 0.1685 | 0.5501 | |
| GSE38129 | SFPQ | 6421 | 201586_s_at | 0.6010 | 0.0000 | |
| GSE45670 | SFPQ | 6421 | 201586_s_at | 0.4720 | 0.0002 | |
| GSE53622 | SFPQ | 6421 | 35569 | 0.2274 | 0.0000 | |
| GSE53624 | SFPQ | 6421 | 27556 | 0.5343 | 0.0000 | |
| GSE63941 | SFPQ | 6421 | 201586_s_at | -0.0177 | 0.9672 | |
| GSE77861 | SFPQ | 6421 | 201586_s_at | 0.4340 | 0.0679 | |
| GSE97050 | SFPQ | 6421 | A_33_P3318292 | 0.2702 | 0.3073 | |
| SRP007169 | SFPQ | 6421 | RNAseq | 0.8485 | 0.0141 | |
| SRP008496 | SFPQ | 6421 | RNAseq | 0.5768 | 0.0062 | |
| SRP064894 | SFPQ | 6421 | RNAseq | 0.3149 | 0.0204 | |
| SRP133303 | SFPQ | 6421 | RNAseq | 0.4507 | 0.0021 | |
| SRP159526 | SFPQ | 6421 | RNAseq | 0.6957 | 0.0693 | |
| SRP193095 | SFPQ | 6421 | RNAseq | 0.3941 | 0.0000 | |
| SRP219564 | SFPQ | 6421 | RNAseq | -0.0529 | 0.7831 | |
| TCGA | SFPQ | 6421 | RNAseq | 0.0983 | 0.0138 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SFPQ expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFPQ:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFPQ | 6421 | 2 | 5 | 23 | |
| GSE20123 | SFPQ | 6421 | 2 | 4 | 24 | |
| GSE43470 | SFPQ | 6421 | 7 | 2 | 34 | |
| GSE46452 | SFPQ | 6421 | 4 | 1 | 54 | |
| GSE47630 | SFPQ | 6421 | 8 | 3 | 29 | |
| GSE54993 | SFPQ | 6421 | 1 | 1 | 68 | |
| GSE54994 | SFPQ | 6421 | 11 | 3 | 39 | |
| GSE60625 | SFPQ | 6421 | 0 | 0 | 11 | |
| GSE74703 | SFPQ | 6421 | 6 | 1 | 29 | |
| GSE74704 | SFPQ | 6421 | 1 | 0 | 19 | |
| TCGA | SFPQ | 6421 | 13 | 18 | 65 |
Total number of gains: 55; Total number of losses: 38; Total Number of normals: 395.
Somatic mutations of SFPQ:
Generating mutation plots.
Highly correlated genes for SFPQ:
Showing top 20/850 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFPQ | SPNS1 | 0.823096 | 3 | 0 | 3 |
| SFPQ | SRSF2 | 0.799943 | 3 | 0 | 3 |
| SFPQ | LACTB | 0.769985 | 3 | 0 | 3 |
| SFPQ | RACGAP1 | 0.759595 | 7 | 0 | 7 |
| SFPQ | ARF3 | 0.756929 | 3 | 0 | 3 |
| SFPQ | TRAPPC10 | 0.754177 | 3 | 0 | 3 |
| SFPQ | BORA | 0.745426 | 6 | 0 | 6 |
| SFPQ | NCAPG | 0.743338 | 6 | 0 | 6 |
| SFPQ | MBIP | 0.741606 | 3 | 0 | 3 |
| SFPQ | CNOT10 | 0.741228 | 3 | 0 | 3 |
| SFPQ | NEK4 | 0.739327 | 4 | 0 | 4 |
| SFPQ | UBR7 | 0.737897 | 3 | 0 | 3 |
| SFPQ | PIP4K2C | 0.734516 | 4 | 0 | 4 |
| SFPQ | PTP4A2 | 0.734063 | 5 | 0 | 4 |
| SFPQ | MCU | 0.726028 | 3 | 0 | 3 |
| SFPQ | TOP2A | 0.722761 | 9 | 0 | 9 |
| SFPQ | SRSF7 | 0.722646 | 9 | 0 | 9 |
| SFPQ | RAB3GAP1 | 0.721789 | 3 | 0 | 3 |
| SFPQ | IMPACT | 0.719157 | 4 | 0 | 3 |
| SFPQ | KIF2C | 0.717914 | 8 | 0 | 7 |
For details and further investigation, click here
