| Full name: SSU72 homolog, RNA polymerase II CTD phosphatase | Alias Symbol: HSPC182 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 29101 | HGNC ID: HGNC:25016 | Ensembl Gene: ENSG00000160075 | OMIM ID: 617680 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SSU72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SSU72 | 29101 | 223051_at | -0.1296 | 0.8163 | |
| GSE26886 | SSU72 | 29101 | 223051_at | 0.4309 | 0.0427 | |
| GSE45670 | SSU72 | 29101 | 223051_at | 0.2194 | 0.0848 | |
| GSE53622 | SSU72 | 29101 | 135736 | -0.1352 | 0.0509 | |
| GSE53624 | SSU72 | 29101 | 135736 | -0.0787 | 0.1179 | |
| GSE63941 | SSU72 | 29101 | 223051_at | -0.4990 | 0.1454 | |
| GSE77861 | SSU72 | 29101 | 223051_at | -0.3796 | 0.1086 | |
| GSE97050 | SSU72 | 29101 | A_23_P63289 | 0.3612 | 0.2495 | |
| SRP007169 | SSU72 | 29101 | RNAseq | -1.1828 | 0.0049 | |
| SRP008496 | SSU72 | 29101 | RNAseq | -0.7906 | 0.0005 | |
| SRP064894 | SSU72 | 29101 | RNAseq | -0.0312 | 0.8964 | |
| SRP133303 | SSU72 | 29101 | RNAseq | -0.1142 | 0.3449 | |
| SRP159526 | SSU72 | 29101 | RNAseq | -0.2530 | 0.3055 | |
| SRP193095 | SSU72 | 29101 | RNAseq | -0.3127 | 0.0102 | |
| SRP219564 | SSU72 | 29101 | RNAseq | -0.0981 | 0.6917 | |
| TCGA | SSU72 | 29101 | RNAseq | 0.0439 | 0.3356 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SSU72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SSU72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SSU72 | 29101 | 3 | 7 | 20 | |
| GSE20123 | SSU72 | 29101 | 3 | 6 | 21 | |
| GSE43470 | SSU72 | 29101 | 3 | 5 | 35 | |
| GSE46452 | SSU72 | 29101 | 7 | 1 | 51 | |
| GSE47630 | SSU72 | 29101 | 8 | 4 | 28 | |
| GSE54993 | SSU72 | 29101 | 2 | 2 | 66 | |
| GSE54994 | SSU72 | 29101 | 15 | 2 | 36 | |
| GSE60625 | SSU72 | 29101 | 0 | 0 | 11 | |
| GSE74703 | SSU72 | 29101 | 3 | 3 | 30 | |
| GSE74704 | SSU72 | 29101 | 3 | 0 | 17 | |
| TCGA | SSU72 | 29101 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of SSU72:
Generating mutation plots.
Highly correlated genes for SSU72:
Showing top 20/228 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SSU72 | TXNDC17 | 0.781977 | 3 | 0 | 3 |
| SSU72 | RB1 | 0.744485 | 3 | 0 | 3 |
| SSU72 | BLOC1S2 | 0.737367 | 4 | 0 | 4 |
| SSU72 | DHCR24 | 0.735346 | 3 | 0 | 3 |
| SSU72 | E2F8 | 0.716438 | 3 | 0 | 3 |
| SSU72 | RNFT1 | 0.712667 | 3 | 0 | 3 |
| SSU72 | LRRC40 | 0.71098 | 3 | 0 | 3 |
| SSU72 | CPT2 | 0.705864 | 3 | 0 | 3 |
| SSU72 | AASDHPPT | 0.704448 | 3 | 0 | 3 |
| SSU72 | ABI1 | 0.704338 | 4 | 0 | 4 |
| SSU72 | GALNT7 | 0.691437 | 3 | 0 | 3 |
| SSU72 | CAPZA1 | 0.68985 | 4 | 0 | 4 |
| SSU72 | GLMN | 0.684044 | 4 | 0 | 3 |
| SSU72 | FAM83G | 0.683041 | 3 | 0 | 3 |
| SSU72 | CDA | 0.679846 | 3 | 0 | 3 |
| SSU72 | PRRC1 | 0.679806 | 4 | 0 | 3 |
| SSU72 | PPP1R8 | 0.679234 | 3 | 0 | 3 |
| SSU72 | DIAPH1 | 0.6729 | 3 | 0 | 3 |
| SSU72 | COQ4 | 0.672603 | 3 | 0 | 3 |
| SSU72 | NOL9 | 0.664365 | 4 | 0 | 4 |
For details and further investigation, click here
