| Full name: ADAM metallopeptidase domain 32 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8p11.22 | ||
| Entrez ID: 203102 | HGNC ID: HGNC:15479 | Ensembl Gene: ENSG00000197140 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADAM32:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAM32 | 203102 | 1552266_at | 0.1336 | 0.6041 | |
| GSE26886 | ADAM32 | 203102 | 1552266_at | 0.1838 | 0.0795 | |
| GSE45670 | ADAM32 | 203102 | 1552266_at | 0.0250 | 0.8885 | |
| GSE53622 | ADAM32 | 203102 | 36414 | -0.4260 | 0.0251 | |
| GSE53624 | ADAM32 | 203102 | 100378 | 0.4755 | 0.0000 | |
| GSE63941 | ADAM32 | 203102 | 1552266_at | -0.1566 | 0.2864 | |
| GSE77861 | ADAM32 | 203102 | 1552266_at | -0.2069 | 0.1589 | |
| GSE97050 | ADAM32 | 203102 | A_33_P3412428 | -0.5187 | 0.1782 | |
| SRP133303 | ADAM32 | 203102 | RNAseq | 0.1332 | 0.5944 | |
| SRP159526 | ADAM32 | 203102 | RNAseq | 0.9176 | 0.0699 | |
| TCGA | ADAM32 | 203102 | RNAseq | 1.2084 | 0.0088 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ADAM32 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAM32:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAM32 | 203102 | 10 | 4 | 16 | |
| GSE20123 | ADAM32 | 203102 | 10 | 4 | 16 | |
| GSE43470 | ADAM32 | 203102 | 8 | 7 | 28 | |
| GSE46452 | ADAM32 | 203102 | 20 | 5 | 34 | |
| GSE47630 | ADAM32 | 203102 | 12 | 7 | 21 | |
| GSE54993 | ADAM32 | 203102 | 2 | 16 | 52 | |
| GSE54994 | ADAM32 | 203102 | 17 | 7 | 29 | |
| GSE60625 | ADAM32 | 203102 | 3 | 0 | 8 | |
| GSE74703 | ADAM32 | 203102 | 8 | 6 | 22 | |
| GSE74704 | ADAM32 | 203102 | 9 | 1 | 10 | |
| TCGA | ADAM32 | 203102 | 35 | 22 | 39 |
Total number of gains: 134; Total number of losses: 79; Total Number of normals: 275.
Somatic mutations of ADAM32:
Generating mutation plots.
Highly correlated genes for ADAM32:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAM32 | TAF1L | 0.7266 | 3 | 0 | 3 |
| ADAM32 | AGPAT3 | 0.723277 | 3 | 0 | 3 |
| ADAM32 | BDNF | 0.714207 | 3 | 0 | 3 |
| ADAM32 | RSPH3 | 0.71403 | 3 | 0 | 3 |
| ADAM32 | USF2 | 0.698612 | 3 | 0 | 3 |
| ADAM32 | NF2 | 0.685497 | 3 | 0 | 3 |
| ADAM32 | BHLHE41 | 0.683739 | 3 | 0 | 3 |
| ADAM32 | SERPINA1 | 0.683403 | 3 | 0 | 3 |
| ADAM32 | C1orf159 | 0.666796 | 3 | 0 | 3 |
| ADAM32 | LRP3 | 0.658997 | 3 | 0 | 3 |
| ADAM32 | NFAM1 | 0.658296 | 3 | 0 | 3 |
| ADAM32 | SNAPC4 | 0.657359 | 3 | 0 | 3 |
| ADAM32 | ZNF578 | 0.650192 | 4 | 0 | 3 |
| ADAM32 | MGAT4A | 0.647949 | 3 | 0 | 3 |
| ADAM32 | CDC42EP1 | 0.646386 | 4 | 0 | 3 |
| ADAM32 | STAG3 | 0.641898 | 3 | 0 | 3 |
| ADAM32 | PIK3R2 | 0.641302 | 3 | 0 | 3 |
| ADAM32 | CATSPER1 | 0.636961 | 3 | 0 | 3 |
| ADAM32 | TMEM52B | 0.632158 | 3 | 0 | 3 |
| ADAM32 | TMSB15B | 0.627532 | 3 | 0 | 3 |
For details and further investigation, click here
