| Full name: stanniocalcin 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8p21.2 | ||
| Entrez ID: 6781 | HGNC ID: HGNC:11373 | Ensembl Gene: ENSG00000159167 | OMIM ID: 601185 |
| Drug and gene relationship at DGIdb | |||
Expression of STC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STC1 | 6781 | 204595_s_at | 0.3958 | 0.7519 | |
| GSE20347 | STC1 | 6781 | 204595_s_at | 1.4631 | 0.0000 | |
| GSE23400 | STC1 | 6781 | 204595_s_at | 0.3801 | 0.0000 | |
| GSE26886 | STC1 | 6781 | 204595_s_at | 2.6029 | 0.0000 | |
| GSE29001 | STC1 | 6781 | 204595_s_at | 0.8151 | 0.0286 | |
| GSE38129 | STC1 | 6781 | 204595_s_at | 0.8674 | 0.0096 | |
| GSE45670 | STC1 | 6781 | 204595_s_at | 1.0672 | 0.0331 | |
| GSE53622 | STC1 | 6781 | 114752 | 0.9159 | 0.0000 | |
| GSE53624 | STC1 | 6781 | 47917 | 1.1675 | 0.0000 | |
| GSE63941 | STC1 | 6781 | 204595_s_at | -2.5412 | 0.1056 | |
| GSE77861 | STC1 | 6781 | 204596_s_at | 0.1100 | 0.2486 | |
| GSE97050 | STC1 | 6781 | A_23_P314755 | 1.2122 | 0.1279 | |
| SRP007169 | STC1 | 6781 | RNAseq | 4.7617 | 0.0000 | |
| SRP008496 | STC1 | 6781 | RNAseq | 4.6663 | 0.0000 | |
| SRP064894 | STC1 | 6781 | RNAseq | 1.5182 | 0.0019 | |
| SRP133303 | STC1 | 6781 | RNAseq | 1.5888 | 0.0000 | |
| SRP159526 | STC1 | 6781 | RNAseq | 1.8712 | 0.0002 | |
| SRP193095 | STC1 | 6781 | RNAseq | 2.6108 | 0.0000 | |
| SRP219564 | STC1 | 6781 | RNAseq | 1.9219 | 0.0046 | |
| TCGA | STC1 | 6781 | RNAseq | -0.1483 | 0.2932 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by STC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STC1 | 6781 | 4 | 12 | 14 | |
| GSE20123 | STC1 | 6781 | 4 | 12 | 14 | |
| GSE43470 | STC1 | 6781 | 4 | 8 | 31 | |
| GSE46452 | STC1 | 6781 | 13 | 13 | 33 | |
| GSE47630 | STC1 | 6781 | 10 | 8 | 22 | |
| GSE54993 | STC1 | 6781 | 2 | 14 | 54 | |
| GSE54994 | STC1 | 6781 | 8 | 18 | 27 | |
| GSE60625 | STC1 | 6781 | 3 | 0 | 8 | |
| GSE74703 | STC1 | 6781 | 4 | 7 | 25 | |
| GSE74704 | STC1 | 6781 | 3 | 8 | 9 | |
| TCGA | STC1 | 6781 | 15 | 42 | 39 |
Total number of gains: 70; Total number of losses: 142; Total Number of normals: 276.
Somatic mutations of STC1:
Generating mutation plots.
Highly correlated genes for STC1:
Showing top 20/860 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STC1 | MICAL1 | 0.702165 | 3 | 0 | 3 |
| STC1 | FAM229B | 0.691269 | 3 | 0 | 3 |
| STC1 | SLC35D3 | 0.686026 | 3 | 0 | 3 |
| STC1 | SAFB2 | 0.685308 | 3 | 0 | 3 |
| STC1 | UHRF1 | 0.671929 | 4 | 0 | 4 |
| STC1 | C19orf54 | 0.660588 | 3 | 0 | 3 |
| STC1 | CDCA2 | 0.659554 | 4 | 0 | 3 |
| STC1 | SLC39A14 | 0.658382 | 11 | 0 | 10 |
| STC1 | TNFAIP6 | 0.657508 | 11 | 0 | 9 |
| STC1 | PGM2L1 | 0.654999 | 5 | 0 | 4 |
| STC1 | SNX5 | 0.654669 | 4 | 0 | 3 |
| STC1 | MMD | 0.649911 | 12 | 0 | 11 |
| STC1 | ITPA | 0.649672 | 3 | 0 | 3 |
| STC1 | SNAPC2 | 0.649384 | 4 | 0 | 4 |
| STC1 | KIFC1 | 0.649249 | 5 | 0 | 4 |
| STC1 | BUB1 | 0.649049 | 5 | 0 | 5 |
| STC1 | MMP7 | 0.646023 | 4 | 0 | 4 |
| STC1 | NGF | 0.641759 | 4 | 0 | 4 |
| STC1 | ZCCHC3 | 0.641643 | 4 | 0 | 4 |
| STC1 | SERPINE1 | 0.641237 | 10 | 0 | 9 |
For details and further investigation, click here
