| Full name: Scm like with four mbt domains 2 | Alias Symbol: KIAA1617 | ||
| Type: protein-coding gene | Cytoband: 10p14 | ||
| Entrez ID: 57713 | HGNC ID: HGNC:20256 | Ensembl Gene: ENSG00000198879 | OMIM ID: 615392 |
| Drug and gene relationship at DGIdb | |||
Expression of SFMBT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SFMBT2 | 57713 | 227210_at | 0.0359 | 0.9807 | |
| GSE26886 | SFMBT2 | 57713 | 232938_at | -0.1103 | 0.2402 | |
| GSE45670 | SFMBT2 | 57713 | 227210_at | -0.1865 | 0.5475 | |
| GSE53622 | SFMBT2 | 57713 | 35426 | 0.2939 | 0.0198 | |
| GSE53624 | SFMBT2 | 57713 | 35426 | 0.3062 | 0.0020 | |
| GSE63941 | SFMBT2 | 57713 | 232938_at | 0.1699 | 0.4056 | |
| GSE77861 | SFMBT2 | 57713 | 232938_at | -0.1286 | 0.2181 | |
| GSE97050 | SFMBT2 | 57713 | A_33_P3387458 | 0.1185 | 0.5647 | |
| SRP007169 | SFMBT2 | 57713 | RNAseq | 1.3455 | 0.0472 | |
| SRP008496 | SFMBT2 | 57713 | RNAseq | 1.0636 | 0.0181 | |
| SRP064894 | SFMBT2 | 57713 | RNAseq | 1.0125 | 0.0021 | |
| SRP133303 | SFMBT2 | 57713 | RNAseq | 0.3036 | 0.1711 | |
| SRP159526 | SFMBT2 | 57713 | RNAseq | 0.5063 | 0.1585 | |
| SRP193095 | SFMBT2 | 57713 | RNAseq | 0.3061 | 0.2382 | |
| SRP219564 | SFMBT2 | 57713 | RNAseq | 1.1850 | 0.0020 | |
| TCGA | SFMBT2 | 57713 | RNAseq | -0.4820 | 0.0209 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by SFMBT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SFMBT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SFMBT2 | 57713 | 4 | 8 | 18 | |
| GSE20123 | SFMBT2 | 57713 | 4 | 7 | 19 | |
| GSE43470 | SFMBT2 | 57713 | 3 | 6 | 34 | |
| GSE46452 | SFMBT2 | 57713 | 2 | 14 | 43 | |
| GSE47630 | SFMBT2 | 57713 | 5 | 15 | 20 | |
| GSE54993 | SFMBT2 | 57713 | 11 | 0 | 59 | |
| GSE54994 | SFMBT2 | 57713 | 4 | 10 | 39 | |
| GSE60625 | SFMBT2 | 57713 | 0 | 0 | 11 | |
| GSE74703 | SFMBT2 | 57713 | 2 | 4 | 30 | |
| GSE74704 | SFMBT2 | 57713 | 1 | 6 | 13 | |
| TCGA | SFMBT2 | 57713 | 19 | 25 | 52 |
Total number of gains: 55; Total number of losses: 95; Total Number of normals: 338.
Somatic mutations of SFMBT2:
Generating mutation plots.
Highly correlated genes for SFMBT2:
Showing top 20/120 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SFMBT2 | CARD8 | 0.734902 | 3 | 0 | 3 |
| SFMBT2 | FCGR1B | 0.717392 | 3 | 0 | 3 |
| SFMBT2 | FFAR2 | 0.700465 | 3 | 0 | 3 |
| SFMBT2 | LACRT | 0.698252 | 3 | 0 | 3 |
| SFMBT2 | TNFSF13B | 0.694808 | 4 | 0 | 3 |
| SFMBT2 | SPINT3 | 0.693093 | 4 | 0 | 4 |
| SFMBT2 | NOG | 0.69036 | 3 | 0 | 3 |
| SFMBT2 | TMEM221 | 0.689096 | 4 | 0 | 3 |
| SFMBT2 | ENPP3 | 0.687427 | 3 | 0 | 3 |
| SFMBT2 | LRRC3 | 0.678558 | 3 | 0 | 3 |
| SFMBT2 | TNFRSF1B | 0.670153 | 4 | 0 | 4 |
| SFMBT2 | EVI2A | 0.667727 | 3 | 0 | 3 |
| SFMBT2 | CDH4 | 0.666001 | 3 | 0 | 3 |
| SFMBT2 | BATF2 | 0.663989 | 4 | 0 | 3 |
| SFMBT2 | PM20D1 | 0.66315 | 3 | 0 | 3 |
| SFMBT2 | TFEC | 0.656183 | 4 | 0 | 4 |
| SFMBT2 | ZNF582-AS1 | 0.655927 | 3 | 0 | 3 |
| SFMBT2 | FMNL1 | 0.650812 | 4 | 0 | 3 |
| SFMBT2 | LRFN4 | 0.648113 | 3 | 0 | 3 |
| SFMBT2 | STAT4 | 0.642023 | 4 | 0 | 3 |
For details and further investigation, click here
