| Full name: ring finger protein 103 | Alias Symbol: hkf-1|KF1 | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 7844 | HGNC ID: HGNC:12859 | Ensembl Gene: ENSG00000239305 | OMIM ID: 602507 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF103:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF103 | 7844 | 202636_at | -0.4328 | 0.2056 | |
| GSE20347 | RNF103 | 7844 | 202636_at | -0.6122 | 0.0000 | |
| GSE23400 | RNF103 | 7844 | 202636_at | -0.4256 | 0.0000 | |
| GSE26886 | RNF103 | 7844 | 202636_at | -0.9007 | 0.0010 | |
| GSE29001 | RNF103 | 7844 | 202636_at | -0.5970 | 0.0115 | |
| GSE38129 | RNF103 | 7844 | 202636_at | -0.5445 | 0.0000 | |
| GSE45670 | RNF103 | 7844 | 202636_at | -0.4618 | 0.0103 | |
| GSE53622 | RNF103 | 7844 | 95562 | -0.6385 | 0.0000 | |
| GSE53624 | RNF103 | 7844 | 95562 | -0.7739 | 0.0000 | |
| GSE63941 | RNF103 | 7844 | 202636_at | -0.8773 | 0.0209 | |
| GSE77861 | RNF103 | 7844 | 202636_at | -0.1114 | 0.4439 | |
| GSE97050 | RNF103 | 7844 | A_23_P56709 | -0.6136 | 0.1218 | |
| SRP007169 | RNF103 | 7844 | RNAseq | -1.1506 | 0.0020 | |
| SRP008496 | RNF103 | 7844 | RNAseq | -0.8780 | 0.0040 | |
| SRP064894 | RNF103 | 7844 | RNAseq | -0.8084 | 0.0000 | |
| SRP133303 | RNF103 | 7844 | RNAseq | -0.1827 | 0.1934 | |
| SRP159526 | RNF103 | 7844 | RNAseq | -0.1315 | 0.6021 | |
| SRP193095 | RNF103 | 7844 | RNAseq | -0.8334 | 0.0000 | |
| SRP219564 | RNF103 | 7844 | RNAseq | -0.6616 | 0.0037 | |
| TCGA | RNF103 | 7844 | RNAseq | -0.3170 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RNF103 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF103:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF103 | 7844 | 9 | 2 | 19 | |
| GSE20123 | RNF103 | 7844 | 9 | 2 | 19 | |
| GSE43470 | RNF103 | 7844 | 3 | 2 | 38 | |
| GSE46452 | RNF103 | 7844 | 2 | 3 | 54 | |
| GSE47630 | RNF103 | 7844 | 7 | 0 | 33 | |
| GSE54993 | RNF103 | 7844 | 0 | 6 | 64 | |
| GSE54994 | RNF103 | 7844 | 10 | 0 | 43 | |
| GSE60625 | RNF103 | 7844 | 0 | 3 | 8 | |
| GSE74703 | RNF103 | 7844 | 3 | 1 | 32 | |
| GSE74704 | RNF103 | 7844 | 7 | 0 | 13 | |
| TCGA | RNF103 | 7844 | 35 | 4 | 57 |
Total number of gains: 85; Total number of losses: 23; Total Number of normals: 380.
Somatic mutations of RNF103:
Generating mutation plots.
Highly correlated genes for RNF103:
Showing top 20/1207 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF103 | HDHD2 | 0.763955 | 3 | 0 | 3 |
| RNF103 | BEX4 | 0.761946 | 11 | 0 | 11 |
| RNF103 | STK19 | 0.734824 | 3 | 0 | 3 |
| RNF103 | NTN4 | 0.723422 | 4 | 0 | 4 |
| RNF103 | CHADL | 0.716521 | 3 | 0 | 3 |
| RNF103 | ARL5A | 0.716048 | 3 | 0 | 3 |
| RNF103 | COBL | 0.711873 | 10 | 0 | 10 |
| RNF103 | METTL14 | 0.710855 | 3 | 0 | 3 |
| RNF103 | CNR1 | 0.708818 | 3 | 0 | 3 |
| RNF103 | GUF1 | 0.70536 | 3 | 0 | 3 |
| RNF103 | IREB2 | 0.704181 | 3 | 0 | 3 |
| RNF103 | TOB2 | 0.699025 | 3 | 0 | 3 |
| RNF103 | FBXW5 | 0.696327 | 3 | 0 | 3 |
| RNF103 | ANAPC16 | 0.687093 | 4 | 0 | 3 |
| RNF103 | CX3CR1 | 0.685221 | 5 | 0 | 5 |
| RNF103 | DNAJC27 | 0.685151 | 4 | 0 | 3 |
| RNF103 | MAN2B2 | 0.684958 | 4 | 0 | 4 |
| RNF103 | SNX18 | 0.682786 | 3 | 0 | 3 |
| RNF103 | FAM172A | 0.682276 | 11 | 0 | 10 |
| RNF103 | LMBRD1 | 0.680041 | 13 | 0 | 12 |
For details and further investigation, click here
