| Full name: serine/threonine kinase 31 | Alias Symbol: TDRD8|SgK396 | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 56164 | HGNC ID: HGNC:11407 | Ensembl Gene: ENSG00000196335 | OMIM ID: 605790 |
| Drug and gene relationship at DGIdb | |||
Expression of STK31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK31 | 56164 | 223883_s_at | 0.7456 | 0.2418 | |
| GSE26886 | STK31 | 56164 | 223883_s_at | 0.8284 | 0.0296 | |
| GSE45670 | STK31 | 56164 | 223883_s_at | 0.8283 | 0.1004 | |
| GSE53622 | STK31 | 56164 | 106804 | 1.2771 | 0.0000 | |
| GSE53624 | STK31 | 56164 | 106804 | 1.3908 | 0.0000 | |
| GSE63941 | STK31 | 56164 | 223883_s_at | 1.5797 | 0.0684 | |
| GSE77861 | STK31 | 56164 | 223883_s_at | 0.1897 | 0.4942 | |
| GSE97050 | STK31 | 56164 | A_33_P3221498 | 0.3489 | 0.4850 | |
| SRP133303 | STK31 | 56164 | RNAseq | 1.5988 | 0.0046 | |
| SRP159526 | STK31 | 56164 | RNAseq | 1.2914 | 0.0899 | |
| TCGA | STK31 | 56164 | RNAseq | 1.1574 | 0.0020 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by STK31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK31 | 56164 | 17 | 1 | 12 | |
| GSE20123 | STK31 | 56164 | 17 | 1 | 12 | |
| GSE43470 | STK31 | 56164 | 4 | 0 | 39 | |
| GSE46452 | STK31 | 56164 | 10 | 2 | 47 | |
| GSE47630 | STK31 | 56164 | 9 | 1 | 30 | |
| GSE54993 | STK31 | 56164 | 0 | 6 | 64 | |
| GSE54994 | STK31 | 56164 | 20 | 2 | 31 | |
| GSE60625 | STK31 | 56164 | 0 | 0 | 11 | |
| GSE74703 | STK31 | 56164 | 4 | 0 | 32 | |
| GSE74704 | STK31 | 56164 | 11 | 1 | 8 | |
| TCGA | STK31 | 56164 | 56 | 4 | 36 |
Total number of gains: 148; Total number of losses: 18; Total Number of normals: 322.
Somatic mutations of STK31:
Generating mutation plots.
Highly correlated genes for STK31:
Showing top 20/102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK31 | PON3 | 0.678407 | 3 | 0 | 3 |
| STK31 | MIPOL1 | 0.671567 | 3 | 0 | 3 |
| STK31 | TM9SF4 | 0.67005 | 4 | 0 | 4 |
| STK31 | FGFR3 | 0.630093 | 3 | 0 | 3 |
| STK31 | NT5C | 0.629418 | 3 | 0 | 3 |
| STK31 | TRPC4AP | 0.62464 | 3 | 0 | 3 |
| STK31 | TMEM107 | 0.615269 | 3 | 0 | 3 |
| STK31 | NCAPD3 | 0.612075 | 3 | 0 | 3 |
| STK31 | LSM14B | 0.609736 | 4 | 0 | 3 |
| STK31 | MPV17L | 0.607543 | 3 | 0 | 3 |
| STK31 | FZD6 | 0.604729 | 3 | 0 | 3 |
| STK31 | E2F5 | 0.592111 | 3 | 0 | 3 |
| STK31 | KRTCAP3 | 0.590166 | 3 | 0 | 3 |
| STK31 | BCL2L1 | 0.59015 | 3 | 0 | 3 |
| STK31 | RALY | 0.587962 | 3 | 0 | 3 |
| STK31 | TGFB1 | 0.587735 | 3 | 0 | 3 |
| STK31 | PIGU | 0.587434 | 3 | 0 | 3 |
| STK31 | INO80B | 0.583307 | 4 | 0 | 3 |
| STK31 | CXADR | 0.580199 | 4 | 0 | 4 |
| STK31 | FBXO41 | 0.577012 | 4 | 0 | 3 |
For details and further investigation, click here
