| Full name: serine/threonine kinase 36 | Alias Symbol: KIAA1278|FU | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 27148 | HGNC ID: HGNC:17209 | Ensembl Gene: ENSG00000163482 | OMIM ID: 607652 |
| Drug and gene relationship at DGIdb | |||
STK36 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05200 | Pathways in cancer |
Expression of STK36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK36 | 27148 | 231806_s_at | -0.2180 | 0.3700 | |
| GSE26886 | STK36 | 27148 | 231806_s_at | -0.0663 | 0.6830 | |
| GSE45670 | STK36 | 27148 | 231806_s_at | 0.0483 | 0.8220 | |
| GSE53622 | STK36 | 27148 | 69744 | 0.1226 | 0.1451 | |
| GSE53624 | STK36 | 27148 | 69744 | 0.0340 | 0.6664 | |
| GSE63941 | STK36 | 27148 | 226166_x_at | -0.9344 | 0.0110 | |
| GSE77861 | STK36 | 27148 | 234005_x_at | 0.0655 | 0.6828 | |
| GSE97050 | STK36 | 27148 | A_23_P335905 | 0.1946 | 0.4438 | |
| SRP007169 | STK36 | 27148 | RNAseq | 0.0604 | 0.9130 | |
| SRP008496 | STK36 | 27148 | RNAseq | 0.6484 | 0.1029 | |
| SRP064894 | STK36 | 27148 | RNAseq | 0.4627 | 0.0130 | |
| SRP133303 | STK36 | 27148 | RNAseq | -0.1446 | 0.3290 | |
| SRP159526 | STK36 | 27148 | RNAseq | 0.2766 | 0.5897 | |
| SRP193095 | STK36 | 27148 | RNAseq | 0.1136 | 0.4327 | |
| SRP219564 | STK36 | 27148 | RNAseq | 0.1294 | 0.5817 | |
| TCGA | STK36 | 27148 | RNAseq | -0.1973 | 0.0057 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by STK36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK36 | 27148 | 1 | 14 | 15 | |
| GSE20123 | STK36 | 27148 | 1 | 13 | 16 | |
| GSE43470 | STK36 | 27148 | 1 | 7 | 35 | |
| GSE46452 | STK36 | 27148 | 0 | 5 | 54 | |
| GSE47630 | STK36 | 27148 | 4 | 5 | 31 | |
| GSE54993 | STK36 | 27148 | 1 | 2 | 67 | |
| GSE54994 | STK36 | 27148 | 8 | 10 | 35 | |
| GSE60625 | STK36 | 27148 | 0 | 3 | 8 | |
| GSE74703 | STK36 | 27148 | 1 | 5 | 30 | |
| GSE74704 | STK36 | 27148 | 1 | 7 | 12 | |
| TCGA | STK36 | 27148 | 11 | 27 | 58 |
Total number of gains: 29; Total number of losses: 98; Total Number of normals: 361.
Somatic mutations of STK36:
Generating mutation plots.
Highly correlated genes for STK36:
Showing top 20/96 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK36 | NOD1 | 0.705475 | 3 | 0 | 3 |
| STK36 | MRC2 | 0.686393 | 3 | 0 | 3 |
| STK36 | FBLN5 | 0.684942 | 3 | 0 | 3 |
| STK36 | PINK1 | 0.652588 | 3 | 0 | 3 |
| STK36 | DDAH1 | 0.650984 | 3 | 0 | 3 |
| STK36 | TMUB2 | 0.64732 | 3 | 0 | 3 |
| STK36 | KRTCAP2 | 0.643766 | 3 | 0 | 3 |
| STK36 | KCTD6 | 0.643589 | 3 | 0 | 3 |
| STK36 | FGF7 | 0.641738 | 3 | 0 | 3 |
| STK36 | TSPAN31 | 0.64128 | 3 | 0 | 3 |
| STK36 | FAM166A | 0.638581 | 3 | 0 | 3 |
| STK36 | PDCD4 | 0.635987 | 3 | 0 | 3 |
| STK36 | GAS6 | 0.633449 | 3 | 0 | 3 |
| STK36 | ZNF566 | 0.629933 | 3 | 0 | 3 |
| STK36 | ELL3 | 0.626995 | 4 | 0 | 4 |
| STK36 | PARM1 | 0.623588 | 3 | 0 | 3 |
| STK36 | SLC38A4 | 0.622826 | 3 | 0 | 3 |
| STK36 | ZNF746 | 0.621551 | 3 | 0 | 3 |
| STK36 | GALNT11 | 0.620765 | 4 | 0 | 4 |
| STK36 | TGOLN2 | 0.619544 | 4 | 0 | 3 |
For details and further investigation, click here
