| Full name: transmembrane and ubiquitin like domain containing 2 | Alias Symbol: MGC3123 | ||
| Type: protein-coding gene | Cytoband: 17q21 | ||
| Entrez ID: 79089 | HGNC ID: HGNC:28459 | Ensembl Gene: ENSG00000168591 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMUB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMUB2 | 79089 | 218419_s_at | -0.1666 | 0.3425 | |
| GSE20347 | TMUB2 | 79089 | 218419_s_at | -0.1274 | 0.3193 | |
| GSE23400 | TMUB2 | 79089 | 218419_s_at | -0.0344 | 0.5265 | |
| GSE26886 | TMUB2 | 79089 | 218419_s_at | 0.0970 | 0.6750 | |
| GSE29001 | TMUB2 | 79089 | 218419_s_at | -0.1031 | 0.6976 | |
| GSE38129 | TMUB2 | 79089 | 218419_s_at | -0.0558 | 0.6039 | |
| GSE45670 | TMUB2 | 79089 | 218419_s_at | -0.0086 | 0.9466 | |
| GSE53622 | TMUB2 | 79089 | 134567 | -0.0244 | 0.6355 | |
| GSE53624 | TMUB2 | 79089 | 134567 | 0.0287 | 0.6285 | |
| GSE63941 | TMUB2 | 79089 | 218419_s_at | -0.1588 | 0.6666 | |
| GSE77861 | TMUB2 | 79089 | 218419_s_at | 0.0150 | 0.9624 | |
| GSE97050 | TMUB2 | 79089 | A_23_P36647 | 0.0322 | 0.8907 | |
| SRP007169 | TMUB2 | 79089 | RNAseq | -0.2084 | 0.5824 | |
| SRP008496 | TMUB2 | 79089 | RNAseq | -0.2014 | 0.3302 | |
| SRP064894 | TMUB2 | 79089 | RNAseq | 0.1780 | 0.2808 | |
| SRP133303 | TMUB2 | 79089 | RNAseq | -0.1509 | 0.3469 | |
| SRP159526 | TMUB2 | 79089 | RNAseq | -0.1932 | 0.2690 | |
| SRP193095 | TMUB2 | 79089 | RNAseq | -0.1696 | 0.0426 | |
| SRP219564 | TMUB2 | 79089 | RNAseq | -0.1146 | 0.6502 | |
| TCGA | TMUB2 | 79089 | RNAseq | 0.0394 | 0.4332 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMUB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMUB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMUB2 | 79089 | 5 | 2 | 23 | |
| GSE20123 | TMUB2 | 79089 | 5 | 2 | 23 | |
| GSE43470 | TMUB2 | 79089 | 1 | 2 | 40 | |
| GSE46452 | TMUB2 | 79089 | 32 | 0 | 27 | |
| GSE47630 | TMUB2 | 79089 | 9 | 0 | 31 | |
| GSE54993 | TMUB2 | 79089 | 3 | 4 | 63 | |
| GSE54994 | TMUB2 | 79089 | 8 | 5 | 40 | |
| GSE60625 | TMUB2 | 79089 | 4 | 0 | 7 | |
| GSE74703 | TMUB2 | 79089 | 1 | 1 | 34 | |
| GSE74704 | TMUB2 | 79089 | 3 | 1 | 16 | |
| TCGA | TMUB2 | 79089 | 23 | 7 | 66 |
Total number of gains: 94; Total number of losses: 24; Total Number of normals: 370.
Somatic mutations of TMUB2:
Generating mutation plots.
Highly correlated genes for TMUB2:
Showing top 20/98 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMUB2 | PNPLA8 | 0.759763 | 3 | 0 | 3 |
| TMUB2 | ITPRIP | 0.75236 | 3 | 0 | 3 |
| TMUB2 | UBQLN1 | 0.732038 | 3 | 0 | 3 |
| TMUB2 | GPCPD1 | 0.72989 | 3 | 0 | 3 |
| TMUB2 | BMP2K | 0.723415 | 3 | 0 | 3 |
| TMUB2 | DNAJA2 | 0.718349 | 3 | 0 | 3 |
| TMUB2 | SLC35C2 | 0.717859 | 3 | 0 | 3 |
| TMUB2 | AUH | 0.713236 | 3 | 0 | 3 |
| TMUB2 | PTGS1 | 0.708391 | 3 | 0 | 3 |
| TMUB2 | RAB7A | 0.70002 | 3 | 0 | 3 |
| TMUB2 | TSHZ2 | 0.696497 | 3 | 0 | 3 |
| TMUB2 | SOCS2 | 0.696441 | 3 | 0 | 3 |
| TMUB2 | DNASE1L1 | 0.691182 | 4 | 0 | 4 |
| TMUB2 | TGOLN2 | 0.678889 | 3 | 0 | 3 |
| TMUB2 | KIF13B | 0.675359 | 4 | 0 | 3 |
| TMUB2 | CXXC5 | 0.672507 | 3 | 0 | 3 |
| TMUB2 | FAHD1 | 0.665384 | 4 | 0 | 3 |
| TMUB2 | SCP2 | 0.663538 | 3 | 0 | 3 |
| TMUB2 | TINF2 | 0.662978 | 3 | 0 | 3 |
| TMUB2 | FUCA1 | 0.662026 | 3 | 0 | 3 |
For details and further investigation, click here
