| Full name: zinc finger protein 746 | Alias Symbol: FLJ31413|PARIS | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 155061 | HGNC ID: HGNC:21948 | Ensembl Gene: ENSG00000181220 | OMIM ID: 613914 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF746:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF746 | 155061 | 225848_at | 0.0854 | 0.8743 | |
| GSE26886 | ZNF746 | 155061 | 225848_at | 0.3623 | 0.1738 | |
| GSE45670 | ZNF746 | 155061 | 225848_at | 0.2896 | 0.0461 | |
| GSE53622 | ZNF746 | 155061 | 15680 | 0.1951 | 0.0124 | |
| GSE53624 | ZNF746 | 155061 | 15680 | 0.4562 | 0.0001 | |
| GSE63941 | ZNF746 | 155061 | 225848_at | -1.5628 | 0.0001 | |
| GSE77861 | ZNF746 | 155061 | 225848_at | 0.7103 | 0.0151 | |
| GSE97050 | ZNF746 | 155061 | A_33_P3330546 | -0.0850 | 0.7449 | |
| SRP007169 | ZNF746 | 155061 | RNAseq | 0.6769 | 0.1534 | |
| SRP008496 | ZNF746 | 155061 | RNAseq | 0.4307 | 0.2248 | |
| SRP064894 | ZNF746 | 155061 | RNAseq | 0.1969 | 0.1283 | |
| SRP133303 | ZNF746 | 155061 | RNAseq | 0.2041 | 0.1987 | |
| SRP159526 | ZNF746 | 155061 | RNAseq | 0.6635 | 0.0309 | |
| SRP193095 | ZNF746 | 155061 | RNAseq | 0.6262 | 0.0000 | |
| SRP219564 | ZNF746 | 155061 | RNAseq | 0.2950 | 0.2494 | |
| TCGA | ZNF746 | 155061 | RNAseq | 0.0534 | 0.4169 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZNF746 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF746:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF746 | 155061 | 2 | 3 | 25 | |
| GSE20123 | ZNF746 | 155061 | 2 | 3 | 25 | |
| GSE43470 | ZNF746 | 155061 | 2 | 5 | 36 | |
| GSE46452 | ZNF746 | 155061 | 7 | 2 | 50 | |
| GSE47630 | ZNF746 | 155061 | 6 | 8 | 26 | |
| GSE54993 | ZNF746 | 155061 | 3 | 3 | 64 | |
| GSE54994 | ZNF746 | 155061 | 5 | 8 | 40 | |
| GSE60625 | ZNF746 | 155061 | 0 | 0 | 11 | |
| GSE74703 | ZNF746 | 155061 | 2 | 4 | 30 | |
| GSE74704 | ZNF746 | 155061 | 1 | 3 | 16 | |
| TCGA | ZNF746 | 155061 | 26 | 27 | 43 |
Total number of gains: 56; Total number of losses: 66; Total Number of normals: 366.
Somatic mutations of ZNF746:
Generating mutation plots.
Highly correlated genes for ZNF746:
Showing top 20/193 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF746 | LTBP1 | 0.696033 | 3 | 0 | 3 |
| ZNF746 | MLXIP | 0.692453 | 3 | 0 | 3 |
| ZNF746 | SRSF10 | 0.684325 | 3 | 0 | 3 |
| ZNF746 | DDR2 | 0.679487 | 3 | 0 | 3 |
| ZNF746 | ROCK2 | 0.673353 | 3 | 0 | 3 |
| ZNF746 | DNM1L | 0.665464 | 4 | 0 | 3 |
| ZNF746 | WNT2 | 0.665289 | 3 | 0 | 3 |
| ZNF746 | COL15A1 | 0.663355 | 3 | 0 | 3 |
| ZNF746 | TMEM231 | 0.663021 | 3 | 0 | 3 |
| ZNF746 | NARS2 | 0.662853 | 3 | 0 | 3 |
| ZNF746 | AKIRIN1 | 0.659579 | 4 | 0 | 4 |
| ZNF746 | TPM1 | 0.657316 | 3 | 0 | 3 |
| ZNF746 | EIF5B | 0.657024 | 3 | 0 | 3 |
| ZNF746 | S100A6 | 0.652889 | 3 | 0 | 3 |
| ZNF746 | CAP1 | 0.651353 | 3 | 0 | 3 |
| ZNF746 | CLIP2 | 0.646309 | 3 | 0 | 3 |
| ZNF746 | ZNF10 | 0.646083 | 4 | 0 | 4 |
| ZNF746 | SLC37A3 | 0.6431 | 8 | 0 | 7 |
| ZNF746 | IGFBP4 | 0.641506 | 3 | 0 | 3 |
| ZNF746 | KRBOX4 | 0.634458 | 3 | 0 | 3 |
For details and further investigation, click here
