| Full name: tetraspanin 1 | Alias Symbol: TSPAN-1|NET-1 | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 10103 | HGNC ID: HGNC:20657 | Ensembl Gene: ENSG00000117472 | OMIM ID: 613170 |
| Drug and gene relationship at DGIdb | |||
Expression of TSPAN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSPAN1 | 10103 | 209114_at | 0.2780 | 0.8756 | |
| GSE20347 | TSPAN1 | 10103 | 209114_at | 0.8484 | 0.0005 | |
| GSE23400 | TSPAN1 | 10103 | 209114_at | 0.1321 | 0.2724 | |
| GSE26886 | TSPAN1 | 10103 | 209114_at | 1.3493 | 0.0038 | |
| GSE29001 | TSPAN1 | 10103 | 209114_at | 0.2580 | 0.3794 | |
| GSE38129 | TSPAN1 | 10103 | 209114_at | 0.6879 | 0.0051 | |
| GSE45670 | TSPAN1 | 10103 | 209114_at | 0.4206 | 0.5787 | |
| GSE53622 | TSPAN1 | 10103 | 54569 | 0.4167 | 0.2249 | |
| GSE53624 | TSPAN1 | 10103 | 54569 | 0.1762 | 0.4915 | |
| GSE63941 | TSPAN1 | 10103 | 209114_at | 3.4679 | 0.0091 | |
| GSE77861 | TSPAN1 | 10103 | 209114_at | 0.4093 | 0.4000 | |
| GSE97050 | TSPAN1 | 10103 | A_23_P160167 | 0.6700 | 0.3313 | |
| SRP064894 | TSPAN1 | 10103 | RNAseq | 0.9462 | 0.0670 | |
| SRP133303 | TSPAN1 | 10103 | RNAseq | 0.6878 | 0.2994 | |
| SRP159526 | TSPAN1 | 10103 | RNAseq | 0.6952 | 0.2849 | |
| SRP193095 | TSPAN1 | 10103 | RNAseq | -0.7434 | 0.2693 | |
| SRP219564 | TSPAN1 | 10103 | RNAseq | 3.1481 | 0.0000 | |
| TCGA | TSPAN1 | 10103 | RNAseq | -0.7792 | 0.0058 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by TSPAN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSPAN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSPAN1 | 10103 | 4 | 3 | 23 | |
| GSE20123 | TSPAN1 | 10103 | 4 | 2 | 24 | |
| GSE43470 | TSPAN1 | 10103 | 5 | 2 | 36 | |
| GSE46452 | TSPAN1 | 10103 | 2 | 1 | 56 | |
| GSE47630 | TSPAN1 | 10103 | 8 | 4 | 28 | |
| GSE54993 | TSPAN1 | 10103 | 0 | 1 | 69 | |
| GSE54994 | TSPAN1 | 10103 | 11 | 2 | 40 | |
| GSE60625 | TSPAN1 | 10103 | 0 | 0 | 11 | |
| GSE74703 | TSPAN1 | 10103 | 4 | 1 | 31 | |
| GSE74704 | TSPAN1 | 10103 | 2 | 0 | 18 | |
| TCGA | TSPAN1 | 10103 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 33; Total Number of normals: 405.
Somatic mutations of TSPAN1:
Generating mutation plots.
Highly correlated genes for TSPAN1:
Showing top 20/302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSPAN1 | STRA6 | 0.729209 | 3 | 0 | 3 |
| TSPAN1 | BCL11A | 0.723686 | 3 | 0 | 3 |
| TSPAN1 | TMEM216 | 0.720809 | 4 | 0 | 3 |
| TSPAN1 | NKRF | 0.705302 | 3 | 0 | 3 |
| TSPAN1 | POLR2J | 0.691541 | 4 | 0 | 4 |
| TSPAN1 | PRIM1 | 0.690049 | 3 | 0 | 3 |
| TSPAN1 | MAGEA11 | 0.680184 | 3 | 0 | 3 |
| TSPAN1 | MED19 | 0.679204 | 3 | 0 | 3 |
| TSPAN1 | CXCR4 | 0.678439 | 3 | 0 | 3 |
| TSPAN1 | TAF4B | 0.672304 | 3 | 0 | 3 |
| TSPAN1 | ACOT4 | 0.659104 | 3 | 0 | 3 |
| TSPAN1 | ZDHHC16 | 0.658159 | 4 | 0 | 4 |
| TSPAN1 | SRI | 0.656453 | 4 | 0 | 3 |
| TSPAN1 | G2E3 | 0.650851 | 3 | 0 | 3 |
| TSPAN1 | C15orf39 | 0.65076 | 3 | 0 | 3 |
| TSPAN1 | ERP27 | 0.646482 | 3 | 0 | 3 |
| TSPAN1 | HSF1 | 0.645728 | 3 | 0 | 3 |
| TSPAN1 | ITPRIPL2 | 0.644329 | 3 | 0 | 3 |
| TSPAN1 | POLRMT | 0.644011 | 3 | 0 | 3 |
| TSPAN1 | CHCHD5 | 0.641729 | 3 | 0 | 3 |
For details and further investigation, click here
