| Full name: deoxyguanosine kinase | Alias Symbol: dGK | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 1716 | HGNC ID: HGNC:2858 | Ensembl Gene: ENSG00000114956 | OMIM ID: 601465 |
| Drug and gene relationship at DGIdb | |||
Expression of DGUOK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DGUOK | 1716 | 209549_s_at | 0.3788 | 0.3212 | |
| GSE20347 | DGUOK | 1716 | 209549_s_at | 0.5302 | 0.0017 | |
| GSE23400 | DGUOK | 1716 | 209549_s_at | 0.4996 | 0.0000 | |
| GSE26886 | DGUOK | 1716 | 209549_s_at | 1.1756 | 0.0000 | |
| GSE29001 | DGUOK | 1716 | 209549_s_at | 0.3580 | 0.0809 | |
| GSE38129 | DGUOK | 1716 | 209549_s_at | 0.6700 | 0.0000 | |
| GSE45670 | DGUOK | 1716 | 209549_s_at | 0.3909 | 0.0087 | |
| GSE53622 | DGUOK | 1716 | 46533 | 0.6813 | 0.0000 | |
| GSE53624 | DGUOK | 1716 | 46533 | 0.7283 | 0.0000 | |
| GSE63941 | DGUOK | 1716 | 209549_s_at | 0.4591 | 0.0851 | |
| GSE77861 | DGUOK | 1716 | 209549_s_at | 0.5762 | 0.0107 | |
| GSE97050 | DGUOK | 1716 | A_24_P285623 | 0.4396 | 0.1623 | |
| SRP007169 | DGUOK | 1716 | RNAseq | 0.3725 | 0.3524 | |
| SRP008496 | DGUOK | 1716 | RNAseq | 0.7184 | 0.0113 | |
| SRP064894 | DGUOK | 1716 | RNAseq | 0.6983 | 0.0037 | |
| SRP133303 | DGUOK | 1716 | RNAseq | 0.6739 | 0.0000 | |
| SRP159526 | DGUOK | 1716 | RNAseq | 0.9755 | 0.0013 | |
| SRP193095 | DGUOK | 1716 | RNAseq | 0.3829 | 0.0013 | |
| SRP219564 | DGUOK | 1716 | RNAseq | 0.8367 | 0.0211 | |
| TCGA | DGUOK | 1716 | RNAseq | 0.2868 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DGUOK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DGUOK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DGUOK | 1716 | 10 | 1 | 19 | |
| GSE20123 | DGUOK | 1716 | 10 | 1 | 19 | |
| GSE43470 | DGUOK | 1716 | 4 | 0 | 39 | |
| GSE46452 | DGUOK | 1716 | 2 | 3 | 54 | |
| GSE47630 | DGUOK | 1716 | 7 | 0 | 33 | |
| GSE54993 | DGUOK | 1716 | 0 | 6 | 64 | |
| GSE54994 | DGUOK | 1716 | 10 | 0 | 43 | |
| GSE60625 | DGUOK | 1716 | 0 | 3 | 8 | |
| GSE74703 | DGUOK | 1716 | 4 | 0 | 32 | |
| GSE74704 | DGUOK | 1716 | 8 | 0 | 12 | |
| TCGA | DGUOK | 1716 | 38 | 2 | 56 |
Total number of gains: 93; Total number of losses: 16; Total Number of normals: 379.
Somatic mutations of DGUOK:
Generating mutation plots.
Highly correlated genes for DGUOK:
Showing top 20/1957 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DGUOK | FYN | 0.793311 | 3 | 0 | 3 |
| DGUOK | SLC39A3 | 0.786383 | 3 | 0 | 3 |
| DGUOK | PET117 | 0.7859 | 3 | 0 | 3 |
| DGUOK | ALKBH6 | 0.781367 | 4 | 0 | 4 |
| DGUOK | A4GALT | 0.778438 | 3 | 0 | 3 |
| DGUOK | PGM2L1 | 0.771424 | 3 | 0 | 3 |
| DGUOK | UCK2 | 0.761582 | 3 | 0 | 3 |
| DGUOK | UCP2 | 0.754963 | 3 | 0 | 3 |
| DGUOK | PDP1 | 0.7544 | 3 | 0 | 3 |
| DGUOK | USP39 | 0.748196 | 12 | 0 | 11 |
| DGUOK | GNG10 | 0.747021 | 3 | 0 | 3 |
| DGUOK | CAD | 0.740921 | 12 | 0 | 12 |
| DGUOK | SSBP4 | 0.736208 | 4 | 0 | 4 |
| DGUOK | SET | 0.734522 | 4 | 0 | 4 |
| DGUOK | KNSTRN | 0.733003 | 7 | 0 | 6 |
| DGUOK | UBE2T | 0.732047 | 8 | 0 | 8 |
| DGUOK | PFDN2 | 0.729758 | 10 | 0 | 10 |
| DGUOK | RPL39L | 0.72801 | 11 | 0 | 10 |
| DGUOK | LRRC8A | 0.727648 | 3 | 0 | 3 |
| DGUOK | MCM6 | 0.724852 | 12 | 0 | 11 |
For details and further investigation, click here
