| Full name: La ribonucleoprotein domain family member 1B | Alias Symbol: FLJ10378|DKFZp434K245|DKFZp686E0316 | ||
| Type: protein-coding gene | Cytoband: 4q28.2 | ||
| Entrez ID: 55132 | HGNC ID: HGNC:24704 | Ensembl Gene: ENSG00000138709 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LARP1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LARP1B | 55132 | 226750_at | 0.1286 | 0.8055 | |
| GSE26886 | LARP1B | 55132 | 226750_at | -0.4999 | 0.1489 | |
| GSE45670 | LARP1B | 55132 | 226750_at | -0.3669 | 0.0432 | |
| GSE53622 | LARP1B | 55132 | 32303 | -0.4019 | 0.0000 | |
| GSE53624 | LARP1B | 55132 | 117094 | -0.2697 | 0.0004 | |
| GSE63941 | LARP1B | 55132 | 226750_at | 0.0915 | 0.9093 | |
| GSE77861 | LARP1B | 55132 | 1554038_at | -0.1306 | 0.1343 | |
| GSE97050 | LARP1B | 55132 | A_33_P3238007 | -0.0713 | 0.8415 | |
| SRP007169 | LARP1B | 55132 | RNAseq | -0.1503 | 0.7550 | |
| SRP008496 | LARP1B | 55132 | RNAseq | 0.0760 | 0.8338 | |
| SRP064894 | LARP1B | 55132 | RNAseq | -0.4931 | 0.0222 | |
| SRP133303 | LARP1B | 55132 | RNAseq | 0.2940 | 0.1389 | |
| SRP159526 | LARP1B | 55132 | RNAseq | -0.1485 | 0.6369 | |
| SRP193095 | LARP1B | 55132 | RNAseq | -0.4022 | 0.0040 | |
| SRP219564 | LARP1B | 55132 | RNAseq | -0.3051 | 0.2808 | |
| TCGA | LARP1B | 55132 | RNAseq | -0.3051 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LARP1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LARP1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LARP1B | 55132 | 0 | 12 | 18 | |
| GSE20123 | LARP1B | 55132 | 0 | 12 | 18 | |
| GSE43470 | LARP1B | 55132 | 0 | 12 | 31 | |
| GSE46452 | LARP1B | 55132 | 1 | 36 | 22 | |
| GSE47630 | LARP1B | 55132 | 0 | 22 | 18 | |
| GSE54993 | LARP1B | 55132 | 9 | 0 | 61 | |
| GSE54994 | LARP1B | 55132 | 1 | 14 | 38 | |
| GSE60625 | LARP1B | 55132 | 0 | 1 | 10 | |
| GSE74703 | LARP1B | 55132 | 0 | 10 | 26 | |
| GSE74704 | LARP1B | 55132 | 0 | 6 | 14 | |
| TCGA | LARP1B | 55132 | 7 | 37 | 52 |
Total number of gains: 18; Total number of losses: 162; Total Number of normals: 308.
Somatic mutations of LARP1B:
Generating mutation plots.
Highly correlated genes for LARP1B:
Showing top 20/145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LARP1B | HNRNPAB | 0.812682 | 3 | 0 | 3 |
| LARP1B | TADA1 | 0.771162 | 3 | 0 | 3 |
| LARP1B | KPNA4 | 0.77014 | 3 | 0 | 3 |
| LARP1B | HCCS | 0.767758 | 3 | 0 | 3 |
| LARP1B | FAM53B | 0.743825 | 3 | 0 | 3 |
| LARP1B | DAZAP1 | 0.74309 | 3 | 0 | 3 |
| LARP1B | MTO1 | 0.737998 | 3 | 0 | 3 |
| LARP1B | ZCCHC8 | 0.732984 | 3 | 0 | 3 |
| LARP1B | PITRM1 | 0.725214 | 3 | 0 | 3 |
| LARP1B | ESCO1 | 0.725044 | 3 | 0 | 3 |
| LARP1B | FBXO33 | 0.723101 | 3 | 0 | 3 |
| LARP1B | CHCHD6 | 0.722113 | 3 | 0 | 3 |
| LARP1B | CHUK | 0.713702 | 4 | 0 | 3 |
| LARP1B | ARL6 | 0.713243 | 3 | 0 | 3 |
| LARP1B | NSD1 | 0.70942 | 3 | 0 | 3 |
| LARP1B | SOS2 | 0.707951 | 3 | 0 | 3 |
| LARP1B | ACVR2A | 0.706008 | 3 | 0 | 3 |
| LARP1B | ANAPC13 | 0.700686 | 3 | 0 | 3 |
| LARP1B | ZNF570 | 0.697233 | 4 | 0 | 3 |
| LARP1B | SRSF7 | 0.697139 | 3 | 0 | 3 |
For details and further investigation, click here
