| Full name: ubiquitin protein ligase E3 component n-recognin 7 (putative) | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.12 | ||
| Entrez ID: 55148 | HGNC ID: HGNC:20344 | Ensembl Gene: ENSG00000012963 | OMIM ID: 613816 |
| Drug and gene relationship at DGIdb | |||
Expression of UBR7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBR7 | 55148 | 218108_at | 0.1755 | 0.4933 | |
| GSE20347 | UBR7 | 55148 | 218108_at | 0.2030 | 0.2192 | |
| GSE23400 | UBR7 | 55148 | 218108_at | 0.5443 | 0.0000 | |
| GSE26886 | UBR7 | 55148 | 218108_at | 0.1499 | 0.5697 | |
| GSE29001 | UBR7 | 55148 | 218108_at | 0.5035 | 0.0609 | |
| GSE38129 | UBR7 | 55148 | 218108_at | 0.2142 | 0.0474 | |
| GSE45670 | UBR7 | 55148 | 218108_at | 0.1214 | 0.4771 | |
| GSE53622 | UBR7 | 55148 | 83276 | 0.0163 | 0.8492 | |
| GSE53624 | UBR7 | 55148 | 83276 | 0.1780 | 0.0033 | |
| GSE63941 | UBR7 | 55148 | 218108_at | 0.4524 | 0.3481 | |
| GSE77861 | UBR7 | 55148 | 218108_at | 0.0454 | 0.9425 | |
| GSE97050 | UBR7 | 55148 | A_24_P159094 | 0.2020 | 0.4439 | |
| SRP007169 | UBR7 | 55148 | RNAseq | 0.5279 | 0.2508 | |
| SRP008496 | UBR7 | 55148 | RNAseq | 0.6304 | 0.0258 | |
| SRP064894 | UBR7 | 55148 | RNAseq | 0.3399 | 0.0072 | |
| SRP133303 | UBR7 | 55148 | RNAseq | 0.4797 | 0.0000 | |
| SRP159526 | UBR7 | 55148 | RNAseq | 0.2659 | 0.4181 | |
| SRP193095 | UBR7 | 55148 | RNAseq | 0.1056 | 0.3301 | |
| SRP219564 | UBR7 | 55148 | RNAseq | 0.4533 | 0.2183 | |
| TCGA | UBR7 | 55148 | RNAseq | -0.0107 | 0.8297 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by UBR7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBR7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBR7 | 55148 | 8 | 5 | 17 | |
| GSE20123 | UBR7 | 55148 | 8 | 4 | 18 | |
| GSE43470 | UBR7 | 55148 | 7 | 3 | 33 | |
| GSE46452 | UBR7 | 55148 | 16 | 3 | 40 | |
| GSE47630 | UBR7 | 55148 | 11 | 8 | 21 | |
| GSE54993 | UBR7 | 55148 | 3 | 8 | 59 | |
| GSE54994 | UBR7 | 55148 | 20 | 4 | 29 | |
| GSE60625 | UBR7 | 55148 | 0 | 2 | 9 | |
| GSE74703 | UBR7 | 55148 | 6 | 3 | 27 | |
| GSE74704 | UBR7 | 55148 | 4 | 3 | 13 | |
| TCGA | UBR7 | 55148 | 29 | 21 | 46 |
Total number of gains: 112; Total number of losses: 64; Total Number of normals: 312.
Somatic mutations of UBR7:
Generating mutation plots.
Highly correlated genes for UBR7:
Showing top 20/797 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBR7 | KLHL36 | 0.808364 | 3 | 0 | 3 |
| UBR7 | ZNF740 | 0.772379 | 3 | 0 | 3 |
| UBR7 | C12orf73 | 0.769375 | 3 | 0 | 3 |
| UBR7 | TADA1 | 0.766652 | 3 | 0 | 3 |
| UBR7 | SCAF4 | 0.762306 | 3 | 0 | 3 |
| UBR7 | CHCHD6 | 0.756477 | 3 | 0 | 3 |
| UBR7 | XAB2 | 0.749258 | 3 | 0 | 3 |
| UBR7 | BAK1 | 0.74293 | 4 | 0 | 3 |
| UBR7 | SFPQ | 0.737897 | 3 | 0 | 3 |
| UBR7 | SMARCA5 | 0.731495 | 3 | 0 | 3 |
| UBR7 | ATG4C | 0.727636 | 4 | 0 | 3 |
| UBR7 | CLN6 | 0.726688 | 3 | 0 | 3 |
| UBR7 | POGK | 0.721273 | 4 | 0 | 3 |
| UBR7 | SLBP | 0.720312 | 6 | 0 | 6 |
| UBR7 | CHCHD5 | 0.717965 | 3 | 0 | 3 |
| UBR7 | C17orf80 | 0.711931 | 4 | 0 | 4 |
| UBR7 | NEURL1B | 0.709784 | 3 | 0 | 3 |
| UBR7 | PRDM15 | 0.708084 | 4 | 0 | 4 |
| UBR7 | ERI3 | 0.703569 | 4 | 0 | 4 |
| UBR7 | YIPF3 | 0.700203 | 3 | 0 | 3 |
For details and further investigation, click here
