| Full name: U2 small nuclear RNA auxiliary factor 2 | Alias Symbol: U2AF65 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 11338 | HGNC ID: HGNC:23156 | Ensembl Gene: ENSG00000063244 | OMIM ID: 191318 |
| Drug and gene relationship at DGIdb | |||
Expression of U2AF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | U2AF2 | 11338 | 218381_s_at | 0.4081 | 0.2320 | |
| GSE20347 | U2AF2 | 11338 | 218381_s_at | 0.4689 | 0.0003 | |
| GSE23400 | U2AF2 | 11338 | 218381_s_at | 0.4043 | 0.0000 | |
| GSE26886 | U2AF2 | 11338 | 218381_s_at | 0.7092 | 0.0044 | |
| GSE29001 | U2AF2 | 11338 | 218381_s_at | 0.4248 | 0.2922 | |
| GSE38129 | U2AF2 | 11338 | 218381_s_at | 0.5106 | 0.0000 | |
| GSE45670 | U2AF2 | 11338 | 218381_s_at | 0.2994 | 0.0016 | |
| GSE53622 | U2AF2 | 11338 | 12074 | 0.3379 | 0.0000 | |
| GSE53624 | U2AF2 | 11338 | 38007 | 0.4838 | 0.0000 | |
| GSE63941 | U2AF2 | 11338 | 218381_s_at | -0.1009 | 0.7177 | |
| GSE77861 | U2AF2 | 11338 | 218381_s_at | 0.4218 | 0.0038 | |
| GSE97050 | U2AF2 | 11338 | A_33_P3302796 | 0.3016 | 0.2486 | |
| SRP007169 | U2AF2 | 11338 | RNAseq | 1.0253 | 0.0173 | |
| SRP008496 | U2AF2 | 11338 | RNAseq | 0.8281 | 0.0048 | |
| SRP064894 | U2AF2 | 11338 | RNAseq | 0.4468 | 0.0161 | |
| SRP133303 | U2AF2 | 11338 | RNAseq | 0.5530 | 0.0000 | |
| SRP159526 | U2AF2 | 11338 | RNAseq | 0.3556 | 0.1079 | |
| SRP193095 | U2AF2 | 11338 | RNAseq | 0.3016 | 0.0001 | |
| SRP219564 | U2AF2 | 11338 | RNAseq | 0.2468 | 0.2360 | |
| TCGA | U2AF2 | 11338 | RNAseq | 0.1784 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by U2AF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of U2AF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | U2AF2 | 11338 | 3 | 4 | 23 | |
| GSE20123 | U2AF2 | 11338 | 3 | 3 | 24 | |
| GSE43470 | U2AF2 | 11338 | 3 | 9 | 31 | |
| GSE46452 | U2AF2 | 11338 | 45 | 1 | 13 | |
| GSE47630 | U2AF2 | 11338 | 8 | 6 | 26 | |
| GSE54993 | U2AF2 | 11338 | 17 | 4 | 49 | |
| GSE54994 | U2AF2 | 11338 | 4 | 13 | 36 | |
| GSE60625 | U2AF2 | 11338 | 9 | 0 | 2 | |
| GSE74703 | U2AF2 | 11338 | 3 | 6 | 27 | |
| GSE74704 | U2AF2 | 11338 | 3 | 1 | 16 | |
| TCGA | U2AF2 | 11338 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 61; Total Number of normals: 310.
Somatic mutations of U2AF2:
Generating mutation plots.
Highly correlated genes for U2AF2:
Showing top 20/1508 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| U2AF2 | ZNF451 | 0.8232 | 4 | 0 | 4 |
| U2AF2 | SGSH | 0.807669 | 3 | 0 | 3 |
| U2AF2 | SUGP1 | 0.799776 | 3 | 0 | 3 |
| U2AF2 | TMTC4 | 0.79398 | 3 | 0 | 3 |
| U2AF2 | TMEM181 | 0.785062 | 3 | 0 | 3 |
| U2AF2 | FAM193A | 0.784483 | 3 | 0 | 3 |
| U2AF2 | TAF3 | 0.777733 | 3 | 0 | 3 |
| U2AF2 | ABCD4 | 0.76477 | 3 | 0 | 3 |
| U2AF2 | ZNF579 | 0.763276 | 4 | 0 | 4 |
| U2AF2 | HAS3 | 0.756737 | 3 | 0 | 3 |
| U2AF2 | CDC42EP4 | 0.753581 | 3 | 0 | 3 |
| U2AF2 | C9orf64 | 0.745244 | 3 | 0 | 3 |
| U2AF2 | TMEM63B | 0.743459 | 4 | 0 | 3 |
| U2AF2 | ZNF791 | 0.738313 | 3 | 0 | 3 |
| U2AF2 | DYRK2 | 0.736014 | 3 | 0 | 3 |
| U2AF2 | RAB1B | 0.730215 | 3 | 0 | 3 |
| U2AF2 | MAPK8IP3 | 0.728225 | 3 | 0 | 3 |
| U2AF2 | FZR1 | 0.725222 | 5 | 0 | 5 |
| U2AF2 | TIPRL | 0.724065 | 3 | 0 | 3 |
| U2AF2 | GLG1 | 0.723088 | 4 | 0 | 4 |
For details and further investigation, click here
