Full name: transport and golgi organization 6 homolog	Alias Symbol: FLJ12688|KIAA1746
Type: protein-coding gene	Cytoband: 16q22.1
Entrez ID: 79613	HGNC ID: HGNC:25749	Ensembl Gene: ENSG00000103047	OMIM ID:
Screen Evidence: Knocking out of this gene by CRIPR/Cas9 screen found 283/325 cell lines had fitness change in Project Score. Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

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Expression of TANGO6:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	TANGO6	79613	226467_at	0.3377	0.4865	Show
GSE26886	TANGO6	79613	226467_at	-0.1011	0.5511	Show
GSE45670	TANGO6	79613	226467_at	0.4241	0.0025	Show
GSE53622	TANGO6	79613	22124	0.2809	0.0008	Show
GSE53624	TANGO6	79613	22124	0.3021	0.0020	Show
GSE63941	TANGO6	79613	226467_at	-0.1758	0.6727	Show
GSE77861	TANGO6	79613	226467_at	0.0977	0.3719	Show
SRP007169	TANGO6	79613	RNAseq	1.4586	0.0024	Show
SRP008496	TANGO6	79613	RNAseq	1.6352	0.0000	Show
SRP064894	TANGO6	79613	RNAseq	0.3476	0.0133	Show
SRP133303	TANGO6	79613	RNAseq	0.2534	0.0791	Show
SRP159526	TANGO6	79613	RNAseq	0.2655	0.2568	Show
SRP193095	TANGO6	79613	RNAseq	0.3480	0.0008	Show
SRP219564	TANGO6	79613	RNAseq	0.2130	0.6029	Show

Upregulated datasets: 2; Downregulated datasets: 0.  Download Data

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Survival by TANGO6 expression:

 

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Copy number change of TANGO6:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	TANGO6	79613	9	1	20	Show
GSE20123	TANGO6	79613	9	1	20	Show
GSE43470	TANGO6	79613	2	8	33	Show
GSE46452	TANGO6	79613	38	1	20	Show
GSE47630	TANGO6	79613	11	8	21	Show
GSE54993	TANGO6	79613	2	4	64	Show
GSE54994	TANGO6	79613	8	10	35	Show
GSE60625	TANGO6	79613	4	0	7	Show
GSE74703	TANGO6	79613	2	5	29	Show
GSE74704	TANGO6	79613	5	0	15	Show
TCGA	TANGO6	79613	30	13	53	Show

Total number of gains: 120; Total number of losses: 51; Total Number of normals: 317.  Download Data

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Somatic mutations of TANGO6:

 

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Highly correlated genes for TANGO6:

 

Showing top 20/117 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
TANGO6	DNAJA3	0.74095	3	0	3
TANGO6	DCTPP1	0.690407	4	0	4
TANGO6	MRPL28	0.684313	5	0	5
TANGO6	SNRNP25	0.676471	4	0	4
TANGO6	TUFM	0.675521	3	0	3
TANGO6	TRAF7	0.658008	3	0	3
TANGO6	PSMD13	0.656618	4	0	4
TANGO6	NDUFAF7	0.641177	3	0	3
TANGO6	MRPS34	0.636171	4	0	4
TANGO6	DUS2	0.635439	5	0	3
TANGO6	SAMM50	0.631346	3	0	3
TANGO6	FARSA	0.631199	3	0	3
TANGO6	INTS9	0.630324	3	0	3
TANGO6	POLR3K	0.626341	5	0	4
TANGO6	PLK1	0.623996	3	0	3
TANGO6	WDR46	0.62328	3	0	3
TANGO6	NMRAL1	0.618373	4	0	4
TANGO6	NDUFV1	0.615875	3	0	3
TANGO6	MRPL44	0.614451	3	0	3
TANGO6	GOT2	0.612711	5	0	4

For details and further investigation, click here