| Full name: small nuclear ribonucleoprotein U11/U12 subunit 25 | Alias Symbol: U11/U12-25K | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 79622 | HGNC ID: HGNC:14161 | Ensembl Gene: ENSG00000161981 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SNRNP25:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRNP25 | 79622 | 218493_at | 0.4276 | 0.5143 | |
| GSE20347 | SNRNP25 | 79622 | 218493_at | 0.7386 | 0.0002 | |
| GSE23400 | SNRNP25 | 79622 | 218493_at | 0.4287 | 0.0000 | |
| GSE26886 | SNRNP25 | 79622 | 218493_at | 0.4542 | 0.0022 | |
| GSE29001 | SNRNP25 | 79622 | 218493_at | 0.7034 | 0.1920 | |
| GSE38129 | SNRNP25 | 79622 | 218493_at | 0.5782 | 0.0003 | |
| GSE45670 | SNRNP25 | 79622 | 218493_at | 0.3664 | 0.0743 | |
| GSE53622 | SNRNP25 | 79622 | 103369 | 0.3035 | 0.0000 | |
| GSE53624 | SNRNP25 | 79622 | 103369 | 0.5347 | 0.0000 | |
| GSE63941 | SNRNP25 | 79622 | 218493_at | -0.1793 | 0.7937 | |
| GSE77861 | SNRNP25 | 79622 | 218493_at | 0.3930 | 0.0675 | |
| GSE97050 | SNRNP25 | 79622 | A_23_P152284 | 0.1792 | 0.6081 | |
| SRP007169 | SNRNP25 | 79622 | RNAseq | 0.9162 | 0.0782 | |
| SRP008496 | SNRNP25 | 79622 | RNAseq | 0.9810 | 0.0087 | |
| SRP064894 | SNRNP25 | 79622 | RNAseq | 0.7534 | 0.0188 | |
| SRP133303 | SNRNP25 | 79622 | RNAseq | 0.9024 | 0.0003 | |
| SRP159526 | SNRNP25 | 79622 | RNAseq | 0.4872 | 0.1538 | |
| SRP193095 | SNRNP25 | 79622 | RNAseq | 0.2345 | 0.0731 | |
| SRP219564 | SNRNP25 | 79622 | RNAseq | 0.1229 | 0.8123 | |
| TCGA | SNRNP25 | 79622 | RNAseq | 0.0311 | 0.6761 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNRNP25 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRNP25:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRNP25 | 79622 | 5 | 5 | 20 | |
| GSE20123 | SNRNP25 | 79622 | 5 | 4 | 21 | |
| GSE43470 | SNRNP25 | 79622 | 3 | 7 | 33 | |
| GSE46452 | SNRNP25 | 79622 | 38 | 1 | 20 | |
| GSE47630 | SNRNP25 | 79622 | 12 | 7 | 21 | |
| GSE54993 | SNRNP25 | 79622 | 3 | 5 | 62 | |
| GSE54994 | SNRNP25 | 79622 | 4 | 10 | 39 | |
| GSE60625 | SNRNP25 | 79622 | 4 | 0 | 7 | |
| GSE74703 | SNRNP25 | 79622 | 3 | 5 | 28 | |
| GSE74704 | SNRNP25 | 79622 | 3 | 2 | 15 | |
| TCGA | SNRNP25 | 79622 | 20 | 15 | 61 |
Total number of gains: 100; Total number of losses: 61; Total Number of normals: 327.
Somatic mutations of SNRNP25:
Generating mutation plots.
Highly correlated genes for SNRNP25:
Showing top 20/1031 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRNP25 | POLR3K | 0.737946 | 12 | 0 | 9 |
| SNRNP25 | TBX20 | 0.717001 | 3 | 0 | 3 |
| SNRNP25 | NTPCR | 0.716289 | 3 | 0 | 3 |
| SNRNP25 | DCTPP1 | 0.714246 | 10 | 0 | 10 |
| SNRNP25 | RNF26 | 0.694644 | 4 | 0 | 3 |
| SNRNP25 | TANGO6 | 0.676471 | 4 | 0 | 4 |
| SNRNP25 | NAV1 | 0.675224 | 4 | 0 | 3 |
| SNRNP25 | CDK4 | 0.670361 | 11 | 0 | 9 |
| SNRNP25 | NTHL1 | 0.669169 | 10 | 0 | 9 |
| SNRNP25 | EMG1 | 0.667054 | 8 | 0 | 7 |
| SNRNP25 | PAGR1 | 0.661584 | 7 | 0 | 7 |
| SNRNP25 | FBLN1 | 0.660803 | 3 | 0 | 3 |
| SNRNP25 | SDCCAG8 | 0.660768 | 3 | 0 | 3 |
| SNRNP25 | MRPS34 | 0.660601 | 10 | 0 | 9 |
| SNRNP25 | ORAI1 | 0.659087 | 4 | 0 | 4 |
| SNRNP25 | ADSL | 0.658616 | 11 | 0 | 10 |
| SNRNP25 | FIBP | 0.65567 | 7 | 0 | 6 |
| SNRNP25 | MRPS23 | 0.653472 | 6 | 0 | 6 |
| SNRNP25 | RNPS1 | 0.653318 | 9 | 0 | 8 |
| SNRNP25 | FXN | 0.653136 | 11 | 0 | 9 |
For details and further investigation, click here
