LRRC39

 

Full name: leucine rich repeat containing 39 Alias Symbol: MGC14816|myomasp
Type: protein-coding gene Cytoband: 1p21.2
Entrez ID: 127495 HGNC ID: HGNC:28228 Ensembl Gene: ENSG00000122477 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of LRRC39:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LRRC39 127495 227532_at 0.1239 0.5523
GSE26886 LRRC39 127495 227532_at -0.0774 0.5289
GSE45670 LRRC39 127495 1559580_at -0.0941 0.6908
GSE63941 LRRC39 127495 227532_at 0.1444 0.4716
GSE77861 LRRC39 127495 227532_at -0.0370 0.7875
GSE97050 LRRC39 127495 A_33_P3300665 0.1729 0.5589
SRP064894 LRRC39 127495 RNAseq 0.7487 0.0351
SRP133303 LRRC39 127495 RNAseq -0.2837 0.2406
SRP159526 LRRC39 127495 RNAseq -0.0412 0.9585
SRP193095 LRRC39 127495 RNAseq -0.2957 0.0744
SRP219564 LRRC39 127495 RNAseq -0.1122 0.7697
TCGA LRRC39 127495 RNAseq -0.0819 0.8693

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by LRRC39 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of LRRC39:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LRRC39 127495 0 10 20
GSE20123 LRRC39 127495 0 10 20
GSE43470 LRRC39 127495 2 6 35
GSE46452 LRRC39 127495 1 1 57
GSE47630 LRRC39 127495 9 5 26
GSE54993 LRRC39 127495 0 1 69
GSE54994 LRRC39 127495 6 3 44
GSE60625 LRRC39 127495 0 0 11
GSE74703 LRRC39 127495 1 5 30
GSE74704 LRRC39 127495 0 6 14
TCGA LRRC39 127495 8 25 63

Total number of gains: 27; Total number of losses: 72; Total Number of normals: 389.  


 

Somatic mutations of LRRC39:

 

Generating mutation plots.

 

Highly correlated genes for LRRC39:

 

Showing top 20/25 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LRRC39CYP1A20.742546303
LRRC39GPR1580.735196303
LRRC39RAPGEF40.712239303
LRRC39TAP20.711048303
LRRC39REL0.70954303
LRRC39PSME10.705482303
LRRC39FNBP1L0.696354404
LRRC39TMEM510.69362303
LRRC39ATF7IP0.692258303
LRRC39CLMN0.688184303
LRRC39BRD90.687905303
LRRC39SYCP20.671614303
LRRC39PPTC70.651803303
LRRC39ADPRHL10.649703303
LRRC39SLC5A30.64362403
LRRC39TDRKH0.638449303
LRRC39TEP10.63781403
LRRC39DCUN1D20.625789403
LRRC39ZNF7060.603388403
LRRC39ZNF5510.599501403

For details and further investigation, click here