| Full name: CD52 molecule | Alias Symbol: HE5|EDDM5 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 1043 | HGNC ID: HGNC:1804 | Ensembl Gene: ENSG00000169442 | OMIM ID: 114280 |
| Drug and gene relationship at DGIdb | |||
Expression of CD52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD52 | 1043 | 204661_at | 0.0845 | 0.9676 | |
| GSE20347 | CD52 | 1043 | 204661_at | -0.5402 | 0.0230 | |
| GSE23400 | CD52 | 1043 | 204661_at | 0.0601 | 0.5611 | |
| GSE26886 | CD52 | 1043 | 204661_at | -0.1767 | 0.5560 | |
| GSE29001 | CD52 | 1043 | 34210_at | -0.4421 | 0.2960 | |
| GSE38129 | CD52 | 1043 | 204661_at | -0.4827 | 0.0606 | |
| GSE45670 | CD52 | 1043 | 34210_at | -0.5020 | 0.2597 | |
| GSE53622 | CD52 | 1043 | 49352 | -0.4727 | 0.0151 | |
| GSE53624 | CD52 | 1043 | 49352 | -0.9159 | 0.0000 | |
| GSE63941 | CD52 | 1043 | 204661_at | 0.4466 | 0.0597 | |
| GSE77861 | CD52 | 1043 | 204661_at | -0.3001 | 0.1063 | |
| GSE97050 | CD52 | 1043 | A_23_P85800 | 1.0272 | 0.1791 | |
| SRP064894 | CD52 | 1043 | RNAseq | 0.9261 | 0.0191 | |
| SRP133303 | CD52 | 1043 | RNAseq | -0.8481 | 0.0060 | |
| SRP159526 | CD52 | 1043 | RNAseq | -1.5182 | 0.0962 | |
| SRP193095 | CD52 | 1043 | RNAseq | -0.6332 | 0.0270 | |
| SRP219564 | CD52 | 1043 | RNAseq | 0.2750 | 0.5814 | |
| TCGA | CD52 | 1043 | RNAseq | 0.2971 | 0.1094 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CD52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD52 | 1043 | 0 | 6 | 24 | |
| GSE20123 | CD52 | 1043 | 0 | 5 | 25 | |
| GSE43470 | CD52 | 1043 | 2 | 6 | 35 | |
| GSE46452 | CD52 | 1043 | 5 | 1 | 53 | |
| GSE47630 | CD52 | 1043 | 8 | 3 | 29 | |
| GSE54993 | CD52 | 1043 | 2 | 1 | 67 | |
| GSE54994 | CD52 | 1043 | 10 | 4 | 39 | |
| GSE60625 | CD52 | 1043 | 0 | 0 | 11 | |
| GSE74703 | CD52 | 1043 | 1 | 4 | 31 | |
| GSE74704 | CD52 | 1043 | 0 | 0 | 20 | |
| TCGA | CD52 | 1043 | 9 | 24 | 63 |
Total number of gains: 37; Total number of losses: 54; Total Number of normals: 397.
Somatic mutations of CD52:
Generating mutation plots.
Highly correlated genes for CD52:
Showing top 20/258 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD52 | CD28 | 0.806418 | 4 | 0 | 4 |
| CD52 | CD37 | 0.791795 | 8 | 0 | 8 |
| CD52 | TBC1D10C | 0.777478 | 7 | 0 | 7 |
| CD52 | DOCK2 | 0.771557 | 11 | 0 | 11 |
| CD52 | CD2 | 0.763757 | 11 | 0 | 10 |
| CD52 | LINC01215 | 0.746999 | 5 | 0 | 5 |
| CD52 | MOCOS | 0.741302 | 3 | 0 | 3 |
| CD52 | CORO1A | 0.740127 | 12 | 0 | 10 |
| CD52 | SLAMF6 | 0.738856 | 5 | 0 | 4 |
| CD52 | SPOCK2 | 0.733615 | 6 | 0 | 6 |
| CD52 | PTPRC | 0.733193 | 10 | 0 | 10 |
| CD52 | TNFAIP8L2 | 0.731158 | 6 | 0 | 5 |
| CD52 | FCRL3 | 0.725527 | 5 | 0 | 5 |
| CD52 | CD3D | 0.725289 | 12 | 0 | 10 |
| CD52 | CD53 | 0.722098 | 8 | 0 | 7 |
| CD52 | MPEG1 | 0.721724 | 5 | 0 | 5 |
| CD52 | SASH3 | 0.719517 | 11 | 0 | 10 |
| CD52 | ABI3 | 0.713976 | 6 | 0 | 6 |
| CD52 | HCST | 0.712517 | 8 | 0 | 7 |
| CD52 | IRF8 | 0.711942 | 11 | 0 | 9 |
For details and further investigation, click here
