| Full name: major facilitator superfamily domain containing 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 113655 | HGNC ID: HGNC:25157 | Ensembl Gene: ENSG00000167700 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MFSD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD3 | 113655 | 227296_at | 0.7729 | 0.0345 | |
| GSE26886 | MFSD3 | 113655 | 227296_at | 0.0254 | 0.9124 | |
| GSE45670 | MFSD3 | 113655 | 227296_at | 0.2538 | 0.0497 | |
| GSE53622 | MFSD3 | 113655 | 24301 | 0.4623 | 0.0000 | |
| GSE53624 | MFSD3 | 113655 | 24301 | 0.4724 | 0.0000 | |
| GSE63941 | MFSD3 | 113655 | 227296_at | 0.5470 | 0.2341 | |
| GSE77861 | MFSD3 | 113655 | 227296_at | -0.1515 | 0.3819 | |
| GSE97050 | MFSD3 | 113655 | A_23_P406350 | 0.5338 | 0.1399 | |
| SRP007169 | MFSD3 | 113655 | RNAseq | -0.8899 | 0.0537 | |
| SRP008496 | MFSD3 | 113655 | RNAseq | -0.7946 | 0.0109 | |
| SRP064894 | MFSD3 | 113655 | RNAseq | 0.5282 | 0.1646 | |
| SRP133303 | MFSD3 | 113655 | RNAseq | 0.1661 | 0.5327 | |
| SRP159526 | MFSD3 | 113655 | RNAseq | 0.6218 | 0.1147 | |
| SRP193095 | MFSD3 | 113655 | RNAseq | 0.1514 | 0.3301 | |
| SRP219564 | MFSD3 | 113655 | RNAseq | 1.3850 | 0.0549 | |
| TCGA | MFSD3 | 113655 | RNAseq | 0.1241 | 0.1822 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MFSD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFSD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD3 | 113655 | 17 | 1 | 12 | |
| GSE20123 | MFSD3 | 113655 | 17 | 1 | 12 | |
| GSE43470 | MFSD3 | 113655 | 16 | 2 | 25 | |
| GSE46452 | MFSD3 | 113655 | 28 | 0 | 31 | |
| GSE47630 | MFSD3 | 113655 | 25 | 1 | 14 | |
| GSE54993 | MFSD3 | 113655 | 0 | 25 | 45 | |
| GSE54994 | MFSD3 | 113655 | 39 | 1 | 13 | |
| GSE60625 | MFSD3 | 113655 | 3 | 4 | 4 | |
| GSE74703 | MFSD3 | 113655 | 14 | 1 | 21 | |
| GSE74704 | MFSD3 | 113655 | 10 | 0 | 10 | |
| TCGA | MFSD3 | 113655 | 63 | 2 | 31 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of MFSD3:
Generating mutation plots.
Highly correlated genes for MFSD3:
Showing top 20/578 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD3 | SLC1A5 | 0.799157 | 3 | 0 | 3 |
| MFSD3 | PRELID1 | 0.779321 | 4 | 0 | 4 |
| MFSD3 | TBCD | 0.77616 | 3 | 0 | 3 |
| MFSD3 | RHBDF2 | 0.76413 | 3 | 0 | 3 |
| MFSD3 | NACC1 | 0.748728 | 3 | 0 | 3 |
| MFSD3 | FLYWCH2 | 0.745598 | 3 | 0 | 3 |
| MFSD3 | CHAMP1 | 0.745168 | 3 | 0 | 3 |
| MFSD3 | BUB1 | 0.736656 | 4 | 0 | 3 |
| MFSD3 | HAVCR2 | 0.732765 | 3 | 0 | 3 |
| MFSD3 | CALML5 | 0.728917 | 3 | 0 | 3 |
| MFSD3 | TMEM223 | 0.726863 | 3 | 0 | 3 |
| MFSD3 | ORAI1 | 0.725579 | 4 | 0 | 4 |
| MFSD3 | NPLOC4 | 0.721415 | 3 | 0 | 3 |
| MFSD3 | ABCF3 | 0.721031 | 4 | 0 | 3 |
| MFSD3 | DPM2 | 0.718076 | 5 | 0 | 5 |
| MFSD3 | LRRC59 | 0.713729 | 3 | 0 | 3 |
| MFSD3 | STX4 | 0.71336 | 3 | 0 | 3 |
| MFSD3 | MMS19 | 0.710066 | 4 | 0 | 4 |
| MFSD3 | PSKH1 | 0.709732 | 3 | 0 | 3 |
| MFSD3 | TBC1D22A | 0.707932 | 4 | 0 | 4 |
For details and further investigation, click here
