| Full name: TBC1 domain family member 24 | Alias Symbol: KIAA1171|TLDC6|DFNA65 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 57465 | HGNC ID: HGNC:29203 | Ensembl Gene: ENSG00000162065 | OMIM ID: 613577 |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D24 | 57465 | 227908_at | 0.6396 | 0.2491 | |
| GSE26886 | TBC1D24 | 57465 | 227908_at | 0.8161 | 0.0088 | |
| GSE45670 | TBC1D24 | 57465 | 227908_at | 0.4883 | 0.0764 | |
| GSE53622 | TBC1D24 | 57465 | 32366 | 0.5522 | 0.0002 | |
| GSE53624 | TBC1D24 | 57465 | 32366 | 1.0998 | 0.0000 | |
| GSE63941 | TBC1D24 | 57465 | 227908_at | -1.3832 | 0.0078 | |
| GSE77861 | TBC1D24 | 57465 | 227632_at | 0.0346 | 0.7353 | |
| SRP007169 | TBC1D24 | 57465 | RNAseq | 1.3495 | 0.0031 | |
| SRP008496 | TBC1D24 | 57465 | RNAseq | 1.9669 | 0.0000 | |
| SRP064894 | TBC1D24 | 57465 | RNAseq | 0.8456 | 0.0000 | |
| SRP133303 | TBC1D24 | 57465 | RNAseq | 0.7912 | 0.0001 | |
| SRP159526 | TBC1D24 | 57465 | RNAseq | 1.0254 | 0.0002 | |
| SRP193095 | TBC1D24 | 57465 | RNAseq | 0.8084 | 0.0000 | |
| SRP219564 | TBC1D24 | 57465 | RNAseq | 0.9842 | 0.0092 | |
| TCGA | TBC1D24 | 57465 | RNAseq | -0.0696 | 0.3282 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by TBC1D24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D24 | 57465 | 5 | 5 | 20 | |
| GSE20123 | TBC1D24 | 57465 | 5 | 4 | 21 | |
| GSE43470 | TBC1D24 | 57465 | 4 | 7 | 32 | |
| GSE46452 | TBC1D24 | 57465 | 38 | 1 | 20 | |
| GSE47630 | TBC1D24 | 57465 | 13 | 6 | 21 | |
| GSE54993 | TBC1D24 | 57465 | 3 | 5 | 62 | |
| GSE54994 | TBC1D24 | 57465 | 5 | 9 | 39 | |
| GSE60625 | TBC1D24 | 57465 | 4 | 0 | 7 | |
| GSE74703 | TBC1D24 | 57465 | 4 | 5 | 27 | |
| GSE74704 | TBC1D24 | 57465 | 3 | 2 | 15 | |
| TCGA | TBC1D24 | 57465 | 20 | 13 | 63 |
Total number of gains: 104; Total number of losses: 57; Total Number of normals: 327.
Somatic mutations of TBC1D24:
Generating mutation plots.
Highly correlated genes for TBC1D24:
Showing top 20/323 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D24 | SLC2A6 | 0.667867 | 3 | 0 | 3 |
| TBC1D24 | ZNF239 | 0.665679 | 3 | 0 | 3 |
| TBC1D24 | PHTF1 | 0.658914 | 4 | 0 | 4 |
| TBC1D24 | HIC1 | 0.653333 | 3 | 0 | 3 |
| TBC1D24 | ANXA5 | 0.648742 | 4 | 0 | 4 |
| TBC1D24 | GNPDA1 | 0.647586 | 5 | 0 | 4 |
| TBC1D24 | SLC12A4 | 0.637844 | 4 | 0 | 4 |
| TBC1D24 | PARVA | 0.635877 | 3 | 0 | 3 |
| TBC1D24 | F8 | 0.633695 | 3 | 0 | 3 |
| TBC1D24 | C1orf216 | 0.633639 | 6 | 0 | 5 |
| TBC1D24 | KLHL29 | 0.633598 | 3 | 0 | 3 |
| TBC1D24 | PITX2 | 0.628348 | 3 | 0 | 3 |
| TBC1D24 | PLAUR | 0.623658 | 4 | 0 | 3 |
| TBC1D24 | FBXO31 | 0.623106 | 3 | 0 | 3 |
| TBC1D24 | GRAMD1A | 0.622305 | 5 | 0 | 4 |
| TBC1D24 | TTC7B | 0.621811 | 4 | 0 | 4 |
| TBC1D24 | FADS2 | 0.620495 | 3 | 0 | 3 |
| TBC1D24 | RAB29 | 0.619627 | 5 | 0 | 4 |
| TBC1D24 | E4F1 | 0.617511 | 3 | 0 | 3 |
| TBC1D24 | ZNF7 | 0.613662 | 4 | 0 | 3 |
For details and further investigation, click here
