| Full name: annexin A5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q27 | ||
| Entrez ID: 308 | HGNC ID: HGNC:543 | Ensembl Gene: ENSG00000164111 | OMIM ID: 131230 |
| Drug and gene relationship at DGIdb | |||
Expression of ANXA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANXA5 | 308 | 200782_at | 0.2019 | 0.6456 | |
| GSE20347 | ANXA5 | 308 | 200782_at | 0.2172 | 0.3263 | |
| GSE23400 | ANXA5 | 308 | 200782_at | 0.5570 | 0.0000 | |
| GSE26886 | ANXA5 | 308 | 200782_at | 0.2575 | 0.3117 | |
| GSE29001 | ANXA5 | 308 | 200782_at | 0.6689 | 0.0315 | |
| GSE38129 | ANXA5 | 308 | 200782_at | 0.1960 | 0.4135 | |
| GSE45670 | ANXA5 | 308 | 200782_at | -0.2391 | 0.3809 | |
| GSE53622 | ANXA5 | 308 | 44280 | 0.5427 | 0.0000 | |
| GSE53624 | ANXA5 | 308 | 44280 | 0.8035 | 0.0000 | |
| GSE63941 | ANXA5 | 308 | 200782_at | -2.6244 | 0.0004 | |
| GSE77861 | ANXA5 | 308 | 200782_at | 0.6456 | 0.0749 | |
| GSE97050 | ANXA5 | 308 | A_23_P69720 | 0.7291 | 0.0780 | |
| SRP007169 | ANXA5 | 308 | RNAseq | 1.2014 | 0.0001 | |
| SRP008496 | ANXA5 | 308 | RNAseq | 1.0786 | 0.0000 | |
| SRP064894 | ANXA5 | 308 | RNAseq | 0.6724 | 0.0002 | |
| SRP133303 | ANXA5 | 308 | RNAseq | 1.0395 | 0.0000 | |
| SRP159526 | ANXA5 | 308 | RNAseq | 0.6130 | 0.0069 | |
| SRP193095 | ANXA5 | 308 | RNAseq | 0.9124 | 0.0000 | |
| SRP219564 | ANXA5 | 308 | RNAseq | 0.5875 | 0.2392 | |
| TCGA | ANXA5 | 308 | RNAseq | 0.0163 | 0.7154 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by ANXA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANXA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANXA5 | 308 | 1 | 13 | 16 | |
| GSE20123 | ANXA5 | 308 | 1 | 13 | 16 | |
| GSE43470 | ANXA5 | 308 | 0 | 13 | 30 | |
| GSE46452 | ANXA5 | 308 | 1 | 36 | 22 | |
| GSE47630 | ANXA5 | 308 | 0 | 22 | 18 | |
| GSE54993 | ANXA5 | 308 | 9 | 0 | 61 | |
| GSE54994 | ANXA5 | 308 | 1 | 10 | 42 | |
| GSE60625 | ANXA5 | 308 | 0 | 1 | 10 | |
| GSE74703 | ANXA5 | 308 | 0 | 11 | 25 | |
| GSE74704 | ANXA5 | 308 | 0 | 7 | 13 | |
| TCGA | ANXA5 | 308 | 8 | 34 | 54 |
Total number of gains: 21; Total number of losses: 160; Total Number of normals: 307.
Somatic mutations of ANXA5:
Generating mutation plots.
Highly correlated genes for ANXA5:
Showing top 20/1180 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANXA5 | SH3RF3 | 0.729988 | 5 | 0 | 5 |
| ANXA5 | LGALS1 | 0.724698 | 13 | 0 | 12 |
| ANXA5 | TNFRSF19 | 0.722439 | 3 | 0 | 3 |
| ANXA5 | CEP170 | 0.714868 | 3 | 0 | 3 |
| ANXA5 | ROBO1 | 0.711859 | 3 | 0 | 3 |
| ANXA5 | LOXL2 | 0.711387 | 11 | 0 | 11 |
| ANXA5 | FADS1 | 0.709314 | 3 | 0 | 3 |
| ANXA5 | CCDC80 | 0.708746 | 3 | 0 | 3 |
| ANXA5 | LRRC8C | 0.707275 | 4 | 0 | 3 |
| ANXA5 | TNS3 | 0.705611 | 12 | 0 | 11 |
| ANXA5 | PEAR1 | 0.699521 | 4 | 0 | 4 |
| ANXA5 | FKBP7 | 0.697693 | 7 | 0 | 5 |
| ANXA5 | C11orf96 | 0.697616 | 3 | 0 | 3 |
| ANXA5 | CCL11 | 0.697394 | 3 | 0 | 3 |
| ANXA5 | VIM | 0.695063 | 12 | 0 | 11 |
| ANXA5 | SPECC1 | 0.692406 | 3 | 0 | 3 |
| ANXA5 | BEND6 | 0.691031 | 5 | 0 | 5 |
| ANXA5 | GPX8 | 0.690722 | 8 | 0 | 6 |
| ANXA5 | TMX3 | 0.686815 | 3 | 0 | 3 |
| ANXA5 | ST3GAL2 | 0.686226 | 6 | 0 | 5 |
For details and further investigation, click here
