| Full name: tubulin folding cofactor B | Alias Symbol: CG22|CKAPI | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 1155 | HGNC ID: HGNC:1989 | Ensembl Gene: ENSG00000105254 | OMIM ID: 601303 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TBCB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBCB | 1155 | 211759_x_at | 0.1458 | 0.5947 | |
| GSE20347 | TBCB | 1155 | 201804_x_at | 0.1885 | 0.3299 | |
| GSE23400 | TBCB | 1155 | 211759_x_at | 0.2954 | 0.0002 | |
| GSE26886 | TBCB | 1155 | 201804_x_at | 0.2782 | 0.2888 | |
| GSE29001 | TBCB | 1155 | 201804_x_at | 0.2154 | 0.6410 | |
| GSE38129 | TBCB | 1155 | 216194_s_at | 0.3587 | 0.0552 | |
| GSE45670 | TBCB | 1155 | 201804_x_at | 0.2864 | 0.1466 | |
| GSE53622 | TBCB | 1155 | 3301 | 0.2210 | 0.0003 | |
| GSE53624 | TBCB | 1155 | 3301 | 0.4759 | 0.0000 | |
| GSE63941 | TBCB | 1155 | 201804_x_at | 0.3140 | 0.4998 | |
| GSE77861 | TBCB | 1155 | 211759_x_at | 0.6434 | 0.0711 | |
| GSE97050 | TBCB | 1155 | A_23_P56249 | 0.1140 | 0.5896 | |
| SRP007169 | TBCB | 1155 | RNAseq | 0.4936 | 0.4209 | |
| SRP008496 | TBCB | 1155 | RNAseq | 0.1805 | 0.6368 | |
| SRP064894 | TBCB | 1155 | RNAseq | 0.9413 | 0.0009 | |
| SRP133303 | TBCB | 1155 | RNAseq | 0.5815 | 0.0268 | |
| SRP159526 | TBCB | 1155 | RNAseq | 0.5404 | 0.0241 | |
| SRP193095 | TBCB | 1155 | RNAseq | 0.3021 | 0.0066 | |
| SRP219564 | TBCB | 1155 | RNAseq | 0.0786 | 0.8274 | |
| TCGA | TBCB | 1155 | RNAseq | 0.2799 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBCB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBCB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBCB | 1155 | 8 | 4 | 18 | |
| GSE20123 | TBCB | 1155 | 8 | 3 | 19 | |
| GSE43470 | TBCB | 1155 | 3 | 7 | 33 | |
| GSE46452 | TBCB | 1155 | 48 | 1 | 10 | |
| GSE47630 | TBCB | 1155 | 9 | 5 | 26 | |
| GSE54993 | TBCB | 1155 | 17 | 3 | 50 | |
| GSE54994 | TBCB | 1155 | 6 | 9 | 38 | |
| GSE60625 | TBCB | 1155 | 9 | 0 | 2 | |
| GSE74703 | TBCB | 1155 | 3 | 4 | 29 | |
| GSE74704 | TBCB | 1155 | 7 | 1 | 12 | |
| TCGA | TBCB | 1155 | 22 | 10 | 64 |
Total number of gains: 140; Total number of losses: 47; Total Number of normals: 301.
Somatic mutations of TBCB:
Generating mutation plots.
Highly correlated genes for TBCB:
Showing top 20/842 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBCB | TRIM47 | 0.760033 | 3 | 0 | 3 |
| TBCB | STRADA | 0.759879 | 3 | 0 | 3 |
| TBCB | SNAPC4 | 0.745052 | 3 | 0 | 3 |
| TBCB | INO80E | 0.744581 | 3 | 0 | 3 |
| TBCB | C1orf35 | 0.740584 | 3 | 0 | 3 |
| TBCB | SP4 | 0.731662 | 3 | 0 | 3 |
| TBCB | DEDD | 0.727421 | 4 | 0 | 3 |
| TBCB | BBX | 0.723895 | 3 | 0 | 3 |
| TBCB | PPP1R35 | 0.712215 | 3 | 0 | 3 |
| TBCB | ZFYVE27 | 0.711621 | 3 | 0 | 3 |
| TBCB | SZT2 | 0.710059 | 3 | 0 | 3 |
| TBCB | PTPN1 | 0.707042 | 3 | 0 | 3 |
| TBCB | ZNF496 | 0.702163 | 4 | 0 | 4 |
| TBCB | PRR12 | 0.700848 | 3 | 0 | 3 |
| TBCB | ZNF792 | 0.698897 | 4 | 0 | 4 |
| TBCB | MICU1 | 0.697652 | 4 | 0 | 4 |
| TBCB | CNNM3 | 0.694512 | 4 | 0 | 4 |
| TBCB | SLC39A1 | 0.69097 | 4 | 0 | 3 |
| TBCB | ANP32B | 0.689832 | 4 | 0 | 3 |
| TBCB | CPSF7 | 0.6878 | 4 | 0 | 3 |
For details and further investigation, click here
