| Full name: transmembrane protein 43 | Alias Symbol: MGC3222|DKFZp586G1919|LUMA | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 79188 | HGNC ID: HGNC:28472 | Ensembl Gene: ENSG00000170876 | OMIM ID: 612048 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM43:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM43 | 79188 | 217795_s_at | -0.4438 | 0.0985 | |
| GSE20347 | TMEM43 | 79188 | 217795_s_at | -0.4397 | 0.0087 | |
| GSE23400 | TMEM43 | 79188 | 217795_s_at | -0.1676 | 0.0061 | |
| GSE26886 | TMEM43 | 79188 | 217795_s_at | -1.1562 | 0.0000 | |
| GSE29001 | TMEM43 | 79188 | 217795_s_at | -0.3652 | 0.0158 | |
| GSE38129 | TMEM43 | 79188 | 217795_s_at | -0.4315 | 0.0005 | |
| GSE45670 | TMEM43 | 79188 | 217795_s_at | -0.5076 | 0.0000 | |
| GSE53622 | TMEM43 | 79188 | 133187 | -0.5150 | 0.0000 | |
| GSE53624 | TMEM43 | 79188 | 133187 | -0.4214 | 0.0000 | |
| GSE63941 | TMEM43 | 79188 | 217795_s_at | -0.4652 | 0.3864 | |
| GSE77861 | TMEM43 | 79188 | 217795_s_at | -0.2404 | 0.1472 | |
| GSE97050 | TMEM43 | 79188 | A_23_P121196 | -0.3867 | 0.1496 | |
| SRP007169 | TMEM43 | 79188 | RNAseq | -0.1081 | 0.7788 | |
| SRP008496 | TMEM43 | 79188 | RNAseq | 0.0172 | 0.9429 | |
| SRP064894 | TMEM43 | 79188 | RNAseq | -0.3766 | 0.0076 | |
| SRP133303 | TMEM43 | 79188 | RNAseq | -0.4695 | 0.0001 | |
| SRP159526 | TMEM43 | 79188 | RNAseq | -0.6027 | 0.0330 | |
| SRP193095 | TMEM43 | 79188 | RNAseq | -0.4089 | 0.0059 | |
| SRP219564 | TMEM43 | 79188 | RNAseq | -0.4266 | 0.1467 | |
| TCGA | TMEM43 | 79188 | RNAseq | 0.0142 | 0.7474 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM43 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM43:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM43 | 79188 | 2 | 17 | 11 | |
| GSE20123 | TMEM43 | 79188 | 2 | 17 | 11 | |
| GSE43470 | TMEM43 | 79188 | 0 | 21 | 22 | |
| GSE46452 | TMEM43 | 79188 | 2 | 17 | 40 | |
| GSE47630 | TMEM43 | 79188 | 2 | 23 | 15 | |
| GSE54993 | TMEM43 | 79188 | 6 | 1 | 63 | |
| GSE54994 | TMEM43 | 79188 | 1 | 32 | 20 | |
| GSE60625 | TMEM43 | 79188 | 5 | 0 | 6 | |
| GSE74703 | TMEM43 | 79188 | 0 | 17 | 19 | |
| GSE74704 | TMEM43 | 79188 | 1 | 10 | 9 | |
| TCGA | TMEM43 | 79188 | 2 | 68 | 26 |
Total number of gains: 23; Total number of losses: 223; Total Number of normals: 242.
Somatic mutations of TMEM43:
Generating mutation plots.
Highly correlated genes for TMEM43:
Showing top 20/1046 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM43 | FIBIN | 0.78347 | 3 | 0 | 3 |
| TMEM43 | TBRG1 | 0.750386 | 3 | 0 | 3 |
| TMEM43 | LRCH1 | 0.745064 | 3 | 0 | 3 |
| TMEM43 | THAP2 | 0.743485 | 3 | 0 | 3 |
| TMEM43 | PPP2CB | 0.743106 | 4 | 0 | 3 |
| TMEM43 | TMEM132C | 0.742164 | 3 | 0 | 3 |
| TMEM43 | SLC2A13 | 0.740861 | 3 | 0 | 3 |
| TMEM43 | VPS29 | 0.735959 | 4 | 0 | 4 |
| TMEM43 | PDK3 | 0.729613 | 3 | 0 | 3 |
| TMEM43 | TMEM106B | 0.729566 | 3 | 0 | 3 |
| TMEM43 | PSMD6 | 0.722671 | 4 | 0 | 3 |
| TMEM43 | RNASE4 | 0.719595 | 5 | 0 | 4 |
| TMEM43 | P2RY12 | 0.716812 | 3 | 0 | 3 |
| TMEM43 | RTCA | 0.713962 | 3 | 0 | 3 |
| TMEM43 | ANGPTL1 | 0.713008 | 5 | 0 | 5 |
| TMEM43 | ROCK1 | 0.712775 | 5 | 0 | 3 |
| TMEM43 | RASSF3 | 0.709996 | 4 | 0 | 3 |
| TMEM43 | EPB41L4A-AS1 | 0.708905 | 3 | 0 | 3 |
| TMEM43 | COX15 | 0.70295 | 4 | 0 | 4 |
| TMEM43 | DLD | 0.702604 | 3 | 0 | 3 |
For details and further investigation, click here
