| Full name: CREB/ATF bZIP transcription factor | Alias Symbol: ZF | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 58487 | HGNC ID: HGNC:24905 | Ensembl Gene: ENSG00000137504 | OMIM ID: 606444 |
| Drug and gene relationship at DGIdb | |||
Expression of CREBZF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CREBZF | 58487 | 202978_s_at | -0.1716 | 0.5436 | |
| GSE20347 | CREBZF | 58487 | 202979_s_at | 0.1320 | 0.6695 | |
| GSE23400 | CREBZF | 58487 | 202978_s_at | 0.3804 | 0.0000 | |
| GSE26886 | CREBZF | 58487 | 225594_at | 0.0563 | 0.9201 | |
| GSE29001 | CREBZF | 58487 | 202979_s_at | -0.0828 | 0.8437 | |
| GSE38129 | CREBZF | 58487 | 202979_s_at | 0.3498 | 0.0848 | |
| GSE45670 | CREBZF | 58487 | 225594_at | 0.2128 | 0.3550 | |
| GSE53622 | CREBZF | 58487 | 148612 | 0.5708 | 0.0000 | |
| GSE53624 | CREBZF | 58487 | 98140 | -0.6206 | 0.0000 | |
| GSE63941 | CREBZF | 58487 | 225594_at | -0.6328 | 0.2923 | |
| GSE77861 | CREBZF | 58487 | 225594_at | 0.3054 | 0.3422 | |
| GSE97050 | CREBZF | 58487 | A_23_P203645 | 0.2239 | 0.4735 | |
| SRP007169 | CREBZF | 58487 | RNAseq | 0.9132 | 0.1180 | |
| SRP008496 | CREBZF | 58487 | RNAseq | 1.3800 | 0.0014 | |
| SRP064894 | CREBZF | 58487 | RNAseq | 0.1638 | 0.5862 | |
| SRP133303 | CREBZF | 58487 | RNAseq | -0.1371 | 0.2959 | |
| SRP159526 | CREBZF | 58487 | RNAseq | -0.2651 | 0.3052 | |
| SRP193095 | CREBZF | 58487 | RNAseq | -0.0549 | 0.6663 | |
| SRP219564 | CREBZF | 58487 | RNAseq | -0.2524 | 0.3545 | |
| TCGA | CREBZF | 58487 | RNAseq | -0.0844 | 0.1411 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CREBZF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CREBZF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CREBZF | 58487 | 4 | 9 | 17 | |
| GSE20123 | CREBZF | 58487 | 4 | 9 | 17 | |
| GSE43470 | CREBZF | 58487 | 3 | 4 | 36 | |
| GSE46452 | CREBZF | 58487 | 6 | 24 | 29 | |
| GSE47630 | CREBZF | 58487 | 2 | 19 | 19 | |
| GSE54993 | CREBZF | 58487 | 8 | 2 | 60 | |
| GSE54994 | CREBZF | 58487 | 5 | 19 | 29 | |
| GSE60625 | CREBZF | 58487 | 0 | 3 | 8 | |
| GSE74703 | CREBZF | 58487 | 2 | 3 | 31 | |
| GSE74704 | CREBZF | 58487 | 3 | 6 | 11 | |
| TCGA | CREBZF | 58487 | 16 | 38 | 42 |
Total number of gains: 53; Total number of losses: 136; Total Number of normals: 299.
Somatic mutations of CREBZF:
Generating mutation plots.
Highly correlated genes for CREBZF:
Showing top 20/240 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CREBZF | ZCCHC8 | 0.751216 | 3 | 0 | 3 |
| CREBZF | TBRG1 | 0.744047 | 3 | 0 | 3 |
| CREBZF | ARIH2 | 0.732123 | 3 | 0 | 3 |
| CREBZF | SARNP | 0.726814 | 4 | 0 | 4 |
| CREBZF | ZNF641 | 0.720998 | 3 | 0 | 3 |
| CREBZF | EED | 0.711309 | 11 | 0 | 10 |
| CREBZF | ANAPC4 | 0.710298 | 3 | 0 | 3 |
| CREBZF | GPD2 | 0.688336 | 4 | 0 | 3 |
| CREBZF | EIF3C | 0.686842 | 3 | 0 | 3 |
| CREBZF | SPAST | 0.680975 | 3 | 0 | 3 |
| CREBZF | ABCB10 | 0.678425 | 3 | 0 | 3 |
| CREBZF | WWP1 | 0.678203 | 3 | 0 | 3 |
| CREBZF | NKTR | 0.672125 | 3 | 0 | 3 |
| CREBZF | PNPLA8 | 0.66465 | 4 | 0 | 3 |
| CREBZF | ALG9 | 0.662443 | 3 | 0 | 3 |
| CREBZF | MDM4 | 0.66169 | 3 | 0 | 3 |
| CREBZF | ZNF398 | 0.66112 | 3 | 0 | 3 |
| CREBZF | AASDHPPT | 0.660454 | 5 | 0 | 5 |
| CREBZF | GATAD1 | 0.652289 | 4 | 0 | 3 |
| CREBZF | FBXO11 | 0.649 | 4 | 0 | 3 |
For details and further investigation, click here
