TECRL

 

Full name: trans-2,3-enoyl-CoA reductase like Alias Symbol: GPSN2L|SRD5A2L2|DKFZp313D0829|DKFZp313B2333|TERL
Type: protein-coding gene Cytoband: 4q13.1
Entrez ID: 253017 HGNC ID: HGNC:27365 Ensembl Gene: ENSG00000205678 OMIM ID: 617242
Drug and gene relationship at DGIdb

 

Expression of TECRL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TECRL 253017 241961_at 0.0206 0.9309
GSE26886 TECRL 253017 241961_at -0.0093 0.9032
GSE45670 TECRL 253017 241961_at 0.0502 0.4025
GSE53622 TECRL 253017 33815 0.4515 0.0013
GSE53624 TECRL 253017 33815 0.4697 0.0003
GSE63941 TECRL 253017 241961_at 0.0250 0.8453
GSE77861 TECRL 253017 241961_at -0.0139 0.8550
GSE97050 TECRL 253017 A_33_P3345831 -0.2241 0.3907
SRP133303 TECRL 253017 RNAseq 0.3105 0.0850
SRP159526 TECRL 253017 RNAseq 0.4365 0.3857
SRP193095 TECRL 253017 RNAseq 0.4446 0.0012
SRP219564 TECRL 253017 RNAseq 0.7391 0.1445

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TECRL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TECRL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TECRL 253017 0 13 17
GSE20123 TECRL 253017 0 13 17
GSE43470 TECRL 253017 1 15 27
GSE46452 TECRL 253017 2 35 22
GSE47630 TECRL 253017 0 19 21
GSE54993 TECRL 253017 7 0 63
GSE54994 TECRL 253017 1 9 43
GSE60625 TECRL 253017 0 0 11
GSE74703 TECRL 253017 1 13 22
GSE74704 TECRL 253017 0 8 12
TCGA TECRL 253017 16 27 53

Total number of gains: 28; Total number of losses: 152; Total Number of normals: 308.  


 

Somatic mutations of TECRL:

 

Generating mutation plots.

 

Highly correlated genes for TECRL:

 

Showing top 20/67 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TECRLALPI0.686834303
TECRLSLC26A50.667285303
TECRLCHRM40.665385303
TECRLTRPC30.653094303
TECRLOR1L60.647767303
TECRLALG110.642867303
TECRLUSP2-AS10.64179303
TECRLSZT20.640405403
TECRLBARHL10.636759303
TECRLLCE1E0.63235303
TECRLZNF2480.628554403
TECRLPPP5C0.615411303
TECRLPRAP10.614432303
TECRLZNF4190.614264404
TECRLC9orf500.612123303
TECRLKLF140.61072303
TECRLCDH240.610425303
TECRLMIOX0.610178303
TECRLOR2AT40.608342303
TECRLRBM170.606254403

For details and further investigation, click here