| Full name: poly(rC) binding protein 2 | Alias Symbol: HNRPE2|hnRNP-E2|HNRNPE2 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 5094 | HGNC ID: HGNC:8648 | Ensembl Gene: ENSG00000197111 | OMIM ID: 601210 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PCBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCBP2 | 5094 | 204031_s_at | -0.0368 | 0.9427 | |
| GSE20347 | PCBP2 | 5094 | 204031_s_at | 0.2112 | 0.0913 | |
| GSE23400 | PCBP2 | 5094 | 204031_s_at | 0.3120 | 0.0000 | |
| GSE26886 | PCBP2 | 5094 | 204031_s_at | 0.1088 | 0.6580 | |
| GSE29001 | PCBP2 | 5094 | 204031_s_at | -0.1718 | 0.6004 | |
| GSE38129 | PCBP2 | 5094 | 204031_s_at | 0.2111 | 0.0703 | |
| GSE45670 | PCBP2 | 5094 | 204031_s_at | 0.0563 | 0.6328 | |
| GSE53622 | PCBP2 | 5094 | 43161 | 0.1312 | 0.0110 | |
| GSE53624 | PCBP2 | 5094 | 43161 | 0.1158 | 0.0270 | |
| GSE63941 | PCBP2 | 5094 | 204031_s_at | 0.0071 | 0.9850 | |
| GSE77861 | PCBP2 | 5094 | 204031_s_at | 0.3910 | 0.0485 | |
| GSE97050 | PCBP2 | 5094 | A_33_P3298492 | -0.0230 | 0.9469 | |
| SRP007169 | PCBP2 | 5094 | RNAseq | 0.2141 | 0.5007 | |
| SRP008496 | PCBP2 | 5094 | RNAseq | 0.0726 | 0.6689 | |
| SRP064894 | PCBP2 | 5094 | RNAseq | -0.0016 | 0.9882 | |
| SRP133303 | PCBP2 | 5094 | RNAseq | 0.1372 | 0.2009 | |
| SRP159526 | PCBP2 | 5094 | RNAseq | 0.2372 | 0.2448 | |
| SRP193095 | PCBP2 | 5094 | RNAseq | -0.0363 | 0.7042 | |
| SRP219564 | PCBP2 | 5094 | RNAseq | -0.0381 | 0.8575 | |
| TCGA | PCBP2 | 5094 | RNAseq | -0.0341 | 0.3618 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCBP2 | 5094 | 7 | 1 | 22 | |
| GSE20123 | PCBP2 | 5094 | 7 | 1 | 22 | |
| GSE43470 | PCBP2 | 5094 | 3 | 0 | 40 | |
| GSE46452 | PCBP2 | 5094 | 7 | 1 | 51 | |
| GSE47630 | PCBP2 | 5094 | 10 | 2 | 28 | |
| GSE54993 | PCBP2 | 5094 | 0 | 5 | 65 | |
| GSE54994 | PCBP2 | 5094 | 4 | 1 | 48 | |
| GSE60625 | PCBP2 | 5094 | 0 | 0 | 11 | |
| GSE74703 | PCBP2 | 5094 | 3 | 0 | 33 | |
| GSE74704 | PCBP2 | 5094 | 5 | 1 | 14 | |
| TCGA | PCBP2 | 5094 | 14 | 11 | 71 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of PCBP2:
Generating mutation plots.
Highly correlated genes for PCBP2:
Showing top 20/686 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCBP2 | TINAGL1 | 0.794184 | 3 | 0 | 3 |
| PCBP2 | PSMD1 | 0.782075 | 3 | 0 | 3 |
| PCBP2 | MKRN1 | 0.736829 | 3 | 0 | 3 |
| PCBP2 | ZFPL1 | 0.729677 | 3 | 0 | 3 |
| PCBP2 | TMEM109 | 0.717619 | 3 | 0 | 3 |
| PCBP2 | MACF1 | 0.715399 | 3 | 0 | 3 |
| PCBP2 | TES | 0.707771 | 3 | 0 | 3 |
| PCBP2 | TMEM208 | 0.705235 | 5 | 0 | 5 |
| PCBP2 | PHB | 0.703228 | 6 | 0 | 5 |
| PCBP2 | PRDX2 | 0.701389 | 4 | 0 | 4 |
| PCBP2 | SNAPIN | 0.699647 | 4 | 0 | 4 |
| PCBP2 | SUPT4H1 | 0.694016 | 4 | 0 | 3 |
| PCBP2 | UBAC1 | 0.6939 | 3 | 0 | 3 |
| PCBP2 | DAG1 | 0.693145 | 4 | 0 | 4 |
| PCBP2 | SPTSSA | 0.691652 | 3 | 0 | 3 |
| PCBP2 | DPP8 | 0.689936 | 5 | 0 | 4 |
| PCBP2 | USP3 | 0.685696 | 3 | 0 | 3 |
| PCBP2 | USP37 | 0.685002 | 3 | 0 | 3 |
| PCBP2 | SUN1 | 0.684989 | 3 | 0 | 3 |
| PCBP2 | SMARCE1 | 0.676097 | 5 | 0 | 3 |
For details and further investigation, click here
