| Full name: procollagen C-endopeptidase enhancer 2 | Alias Symbol: PCPE2 | ||
| Type: protein-coding gene | Cytoband: 3q23 | ||
| Entrez ID: 26577 | HGNC ID: HGNC:8739 | Ensembl Gene: ENSG00000163710 | OMIM ID: 607064 |
| Drug and gene relationship at DGIdb | |||
Expression of PCOLCE2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCOLCE2 | 26577 | 219295_s_at | -1.6636 | 0.4100 | |
| GSE20347 | PCOLCE2 | 26577 | 219295_s_at | 1.3277 | 0.0076 | |
| GSE23400 | PCOLCE2 | 26577 | 219295_s_at | -0.6000 | 0.0003 | |
| GSE26886 | PCOLCE2 | 26577 | 219295_s_at | 1.1882 | 0.0027 | |
| GSE29001 | PCOLCE2 | 26577 | 219295_s_at | 1.0672 | 0.1855 | |
| GSE38129 | PCOLCE2 | 26577 | 219295_s_at | -0.1693 | 0.8032 | |
| GSE45670 | PCOLCE2 | 26577 | 219295_s_at | -2.4087 | 0.0038 | |
| GSE53622 | PCOLCE2 | 26577 | 46707 | -0.7257 | 0.0005 | |
| GSE53624 | PCOLCE2 | 26577 | 46707 | -0.4382 | 0.0415 | |
| GSE63941 | PCOLCE2 | 26577 | 219295_s_at | -1.2324 | 0.4380 | |
| GSE77861 | PCOLCE2 | 26577 | 219295_s_at | 0.4910 | 0.0709 | |
| GSE97050 | PCOLCE2 | 26577 | A_23_P57709 | -1.1110 | 0.1798 | |
| SRP064894 | PCOLCE2 | 26577 | RNAseq | -2.0275 | 0.0000 | |
| SRP133303 | PCOLCE2 | 26577 | RNAseq | 0.2309 | 0.6796 | |
| SRP159526 | PCOLCE2 | 26577 | RNAseq | -0.1523 | 0.8439 | |
| TCGA | PCOLCE2 | 26577 | RNAseq | -0.4109 | 0.2295 |
Upregulated datasets: 2; Downregulated datasets: 2.
Survival by PCOLCE2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCOLCE2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCOLCE2 | 26577 | 20 | 0 | 10 | |
| GSE20123 | PCOLCE2 | 26577 | 20 | 0 | 10 | |
| GSE43470 | PCOLCE2 | 26577 | 22 | 0 | 21 | |
| GSE46452 | PCOLCE2 | 26577 | 15 | 4 | 40 | |
| GSE47630 | PCOLCE2 | 26577 | 19 | 3 | 18 | |
| GSE54993 | PCOLCE2 | 26577 | 1 | 8 | 61 | |
| GSE54994 | PCOLCE2 | 26577 | 34 | 1 | 18 | |
| GSE60625 | PCOLCE2 | 26577 | 0 | 6 | 5 | |
| GSE74703 | PCOLCE2 | 26577 | 19 | 0 | 17 | |
| GSE74704 | PCOLCE2 | 26577 | 14 | 0 | 6 | |
| TCGA | PCOLCE2 | 26577 | 64 | 3 | 29 |
Total number of gains: 228; Total number of losses: 25; Total Number of normals: 235.
Somatic mutations of PCOLCE2:
Generating mutation plots.
Highly correlated genes for PCOLCE2:
Showing top 20/762 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCOLCE2 | SGTB | 0.725927 | 3 | 0 | 3 |
| PCOLCE2 | RASD2 | 0.725653 | 3 | 0 | 3 |
| PCOLCE2 | TES | 0.721148 | 3 | 0 | 3 |
| PCOLCE2 | PDZD4 | 0.720087 | 3 | 0 | 3 |
| PCOLCE2 | PDZRN4 | 0.714853 | 6 | 0 | 5 |
| PCOLCE2 | TMOD1 | 0.712482 | 6 | 0 | 5 |
| PCOLCE2 | HOXA4 | 0.708388 | 5 | 0 | 5 |
| PCOLCE2 | LRRC23 | 0.703753 | 3 | 0 | 3 |
| PCOLCE2 | RNASE4 | 0.698866 | 6 | 0 | 5 |
| PCOLCE2 | MYOC | 0.698369 | 7 | 0 | 6 |
| PCOLCE2 | KITLG | 0.692841 | 3 | 0 | 3 |
| PCOLCE2 | GPRASP1 | 0.687014 | 7 | 0 | 7 |
| PCOLCE2 | NOVA1 | 0.6869 | 6 | 0 | 6 |
| PCOLCE2 | ZNF496 | 0.681541 | 3 | 0 | 3 |
| PCOLCE2 | REEP1 | 0.681279 | 7 | 0 | 6 |
| PCOLCE2 | FXYD1 | 0.676927 | 6 | 0 | 5 |
| PCOLCE2 | LIG3 | 0.676762 | 3 | 0 | 3 |
| PCOLCE2 | TCEAL2 | 0.671422 | 8 | 0 | 7 |
| PCOLCE2 | ANKS1B | 0.670066 | 3 | 0 | 3 |
| PCOLCE2 | C7 | 0.669103 | 6 | 0 | 6 |
For details and further investigation, click here
