| Full name: testis associated actin remodelling kinase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 7016 | HGNC ID: HGNC:11731 | Ensembl Gene: ENSG00000107140 | OMIM ID: 601782 |
| Drug and gene relationship at DGIdb | |||
Expression of TESK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TESK1 | 7016 | 204106_at | 0.1272 | 0.7828 | |
| GSE20347 | TESK1 | 7016 | 204106_at | 0.1166 | 0.3498 | |
| GSE23400 | TESK1 | 7016 | 204106_at | 0.0334 | 0.5953 | |
| GSE26886 | TESK1 | 7016 | 204106_at | 1.5655 | 0.0000 | |
| GSE29001 | TESK1 | 7016 | 204106_at | 0.3386 | 0.0359 | |
| GSE38129 | TESK1 | 7016 | 204106_at | -0.0155 | 0.9041 | |
| GSE45670 | TESK1 | 7016 | 204106_at | -0.1023 | 0.4319 | |
| GSE63941 | TESK1 | 7016 | 204106_at | -0.6328 | 0.0805 | |
| GSE77861 | TESK1 | 7016 | 204106_at | -0.1303 | 0.4078 | |
| GSE97050 | TESK1 | 7016 | A_23_P169178 | 0.0877 | 0.6869 | |
| SRP007169 | TESK1 | 7016 | RNAseq | 0.7516 | 0.1644 | |
| SRP008496 | TESK1 | 7016 | RNAseq | 0.9068 | 0.0372 | |
| SRP064894 | TESK1 | 7016 | RNAseq | 0.7349 | 0.0009 | |
| SRP133303 | TESK1 | 7016 | RNAseq | 0.3362 | 0.0429 | |
| SRP159526 | TESK1 | 7016 | RNAseq | 0.3332 | 0.0466 | |
| SRP193095 | TESK1 | 7016 | RNAseq | 0.5813 | 0.0013 | |
| SRP219564 | TESK1 | 7016 | RNAseq | 0.5106 | 0.2527 | |
| TCGA | TESK1 | 7016 | RNAseq | -0.0546 | 0.3265 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TESK1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TESK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TESK1 | 7016 | 3 | 12 | 15 | |
| GSE20123 | TESK1 | 7016 | 3 | 12 | 15 | |
| GSE43470 | TESK1 | 7016 | 3 | 10 | 30 | |
| GSE46452 | TESK1 | 7016 | 6 | 15 | 38 | |
| GSE47630 | TESK1 | 7016 | 1 | 20 | 19 | |
| GSE54993 | TESK1 | 7016 | 6 | 0 | 64 | |
| GSE54994 | TESK1 | 7016 | 6 | 12 | 35 | |
| GSE60625 | TESK1 | 7016 | 0 | 0 | 11 | |
| GSE74703 | TESK1 | 7016 | 2 | 7 | 27 | |
| GSE74704 | TESK1 | 7016 | 0 | 10 | 10 | |
| TCGA | TESK1 | 7016 | 17 | 44 | 35 |
Total number of gains: 47; Total number of losses: 142; Total Number of normals: 299.
Somatic mutations of TESK1:
Generating mutation plots.
Highly correlated genes for TESK1:
Showing top 20/470 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TESK1 | CIDEC | 0.831166 | 3 | 0 | 3 |
| TESK1 | ZNF579 | 0.81003 | 3 | 0 | 3 |
| TESK1 | SLC39A3 | 0.807981 | 3 | 0 | 3 |
| TESK1 | SSBP4 | 0.792721 | 3 | 0 | 3 |
| TESK1 | ZNF414 | 0.789404 | 3 | 0 | 3 |
| TESK1 | DTNBP1 | 0.773156 | 3 | 0 | 3 |
| TESK1 | MRPL55 | 0.771841 | 3 | 0 | 3 |
| TESK1 | LENG8 | 0.755208 | 3 | 0 | 3 |
| TESK1 | ITGA3 | 0.754966 | 3 | 0 | 3 |
| TESK1 | FHOD1 | 0.748029 | 3 | 0 | 3 |
| TESK1 | CAMTA1 | 0.74472 | 3 | 0 | 3 |
| TESK1 | GPR153 | 0.742501 | 3 | 0 | 3 |
| TESK1 | TMEM145 | 0.727874 | 3 | 0 | 3 |
| TESK1 | FBLIM1 | 0.726394 | 3 | 0 | 3 |
| TESK1 | KHSRP | 0.721443 | 4 | 0 | 4 |
| TESK1 | MEA1 | 0.719485 | 4 | 0 | 3 |
| TESK1 | IFT20 | 0.714596 | 4 | 0 | 3 |
| TESK1 | HMX2 | 0.711876 | 3 | 0 | 3 |
| TESK1 | BATF3 | 0.70849 | 3 | 0 | 3 |
| TESK1 | CUTA | 0.707688 | 5 | 0 | 4 |
For details and further investigation, click here
