| Full name: NOP9 nucleolar protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 161424 | HGNC ID: HGNC:19826 | Ensembl Gene: ENSG00000196943 | OMIM ID: 618308 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NOP9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOP9 | 161424 | 225514_at | 0.4357 | 0.4980 | |
| GSE26886 | NOP9 | 161424 | 225514_at | 0.3270 | 0.1548 | |
| GSE45670 | NOP9 | 161424 | 225514_at | 0.2435 | 0.0442 | |
| GSE53622 | NOP9 | 161424 | 74547 | 0.0987 | 0.3203 | |
| GSE53624 | NOP9 | 161424 | 74547 | 0.1142 | 0.1887 | |
| GSE63941 | NOP9 | 161424 | 225514_at | 0.1542 | 0.7988 | |
| GSE77861 | NOP9 | 161424 | 225514_at | -0.0960 | 0.6768 | |
| SRP007169 | NOP9 | 161424 | RNAseq | 0.3422 | 0.3908 | |
| SRP008496 | NOP9 | 161424 | RNAseq | -0.0483 | 0.8514 | |
| SRP064894 | NOP9 | 161424 | RNAseq | 0.0342 | 0.8270 | |
| SRP133303 | NOP9 | 161424 | RNAseq | 0.1462 | 0.4459 | |
| SRP159526 | NOP9 | 161424 | RNAseq | -0.0380 | 0.8344 | |
| SRP193095 | NOP9 | 161424 | RNAseq | 0.0452 | 0.7352 | |
| SRP219564 | NOP9 | 161424 | RNAseq | -0.2851 | 0.3493 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOP9 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NOP9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOP9 | 161424 | 8 | 3 | 19 | |
| GSE20123 | NOP9 | 161424 | 8 | 3 | 19 | |
| GSE43470 | NOP9 | 161424 | 8 | 2 | 33 | |
| GSE46452 | NOP9 | 161424 | 16 | 2 | 41 | |
| GSE47630 | NOP9 | 161424 | 11 | 10 | 19 | |
| GSE54993 | NOP9 | 161424 | 3 | 11 | 56 | |
| GSE54994 | NOP9 | 161424 | 18 | 5 | 30 | |
| GSE60625 | NOP9 | 161424 | 0 | 2 | 9 | |
| GSE74703 | NOP9 | 161424 | 7 | 2 | 27 | |
| GSE74704 | NOP9 | 161424 | 3 | 2 | 15 | |
| TCGA | NOP9 | 161424 | 27 | 12 | 57 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of NOP9:
Generating mutation plots.
Highly correlated genes for NOP9:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOP9 | ZNF530 | 0.727161 | 3 | 0 | 3 |
| NOP9 | METTL3 | 0.661334 | 4 | 0 | 4 |
| NOP9 | CD47 | 0.631845 | 3 | 0 | 3 |
| NOP9 | MRPL52 | 0.62467 | 6 | 0 | 5 |
| NOP9 | METTL17 | 0.602545 | 3 | 0 | 3 |
| NOP9 | THEM5 | 0.600343 | 3 | 0 | 3 |
| NOP9 | EIF2S1 | 0.588638 | 5 | 0 | 4 |
| NOP9 | KPTN | 0.585613 | 5 | 0 | 5 |
| NOP9 | MRPS15 | 0.584607 | 4 | 0 | 3 |
| NOP9 | NEDD8 | 0.582054 | 7 | 0 | 6 |
| NOP9 | TMEM177 | 0.577173 | 3 | 0 | 3 |
| NOP9 | DOHH | 0.575778 | 4 | 0 | 3 |
| NOP9 | BCL2L2 | 0.574946 | 4 | 0 | 3 |
| NOP9 | IPO4 | 0.573662 | 7 | 0 | 4 |
| NOP9 | PRMT5 | 0.572584 | 4 | 0 | 3 |
| NOP9 | PINX1 | 0.571451 | 5 | 0 | 4 |
| NOP9 | INTS1 | 0.571067 | 3 | 0 | 3 |
| NOP9 | ELOVL3 | 0.570279 | 4 | 0 | 3 |
| NOP9 | PSMB5 | 0.565139 | 5 | 0 | 3 |
| NOP9 | ADCK5 | 0.564977 | 4 | 0 | 3 |
For details and further investigation, click here
