| Full name: threonine synthase like 2 | Alias Symbol: FLJ10916|TSH2|SOFAT | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 55258 | HGNC ID: HGNC:25602 | Ensembl Gene: ENSG00000144115 | OMIM ID: 611261 |
| Drug and gene relationship at DGIdb | |||
Expression of THNSL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THNSL2 | 55258 | 219044_at | 0.1213 | 0.9322 | |
| GSE20347 | THNSL2 | 55258 | 219044_at | -0.0698 | 0.8134 | |
| GSE23400 | THNSL2 | 55258 | 219044_at | 0.0192 | 0.8175 | |
| GSE26886 | THNSL2 | 55258 | 219044_at | 0.9986 | 0.0024 | |
| GSE29001 | THNSL2 | 55258 | 219044_at | 0.3556 | 0.1962 | |
| GSE38129 | THNSL2 | 55258 | 219044_at | -0.0184 | 0.9514 | |
| GSE45670 | THNSL2 | 55258 | 219044_at | -0.0867 | 0.8105 | |
| GSE53622 | THNSL2 | 55258 | 95054 | 0.2410 | 0.0926 | |
| GSE53624 | THNSL2 | 55258 | 95054 | 0.1912 | 0.1230 | |
| GSE63941 | THNSL2 | 55258 | 219044_at | 0.6806 | 0.4996 | |
| GSE77861 | THNSL2 | 55258 | 219044_at | -0.0064 | 0.9763 | |
| GSE97050 | THNSL2 | 55258 | A_23_P259207 | -0.2908 | 0.4878 | |
| SRP064894 | THNSL2 | 55258 | RNAseq | 0.5407 | 0.2313 | |
| SRP133303 | THNSL2 | 55258 | RNAseq | -0.0881 | 0.8107 | |
| SRP159526 | THNSL2 | 55258 | RNAseq | 1.1116 | 0.2839 | |
| SRP193095 | THNSL2 | 55258 | RNAseq | 0.8619 | 0.0016 | |
| SRP219564 | THNSL2 | 55258 | RNAseq | 0.8244 | 0.2962 | |
| TCGA | THNSL2 | 55258 | RNAseq | -0.0945 | 0.7000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THNSL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THNSL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THNSL2 | 55258 | 9 | 2 | 19 | |
| GSE20123 | THNSL2 | 55258 | 9 | 2 | 19 | |
| GSE43470 | THNSL2 | 55258 | 3 | 2 | 38 | |
| GSE46452 | THNSL2 | 55258 | 2 | 3 | 54 | |
| GSE47630 | THNSL2 | 55258 | 7 | 0 | 33 | |
| GSE54993 | THNSL2 | 55258 | 0 | 6 | 64 | |
| GSE54994 | THNSL2 | 55258 | 10 | 0 | 43 | |
| GSE60625 | THNSL2 | 55258 | 0 | 3 | 8 | |
| GSE74703 | THNSL2 | 55258 | 3 | 1 | 32 | |
| GSE74704 | THNSL2 | 55258 | 7 | 0 | 13 | |
| TCGA | THNSL2 | 55258 | 34 | 4 | 58 |
Total number of gains: 84; Total number of losses: 23; Total Number of normals: 381.
Somatic mutations of THNSL2:
Generating mutation plots.
Highly correlated genes for THNSL2:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THNSL2 | SDCCAG8 | 0.697781 | 3 | 0 | 3 |
| THNSL2 | HOXA11 | 0.684032 | 3 | 0 | 3 |
| THNSL2 | SFRP1 | 0.678299 | 3 | 0 | 3 |
| THNSL2 | ZBTB24 | 0.668035 | 4 | 0 | 4 |
| THNSL2 | NRK | 0.652562 | 3 | 0 | 3 |
| THNSL2 | C6orf226 | 0.626936 | 3 | 0 | 3 |
| THNSL2 | MRPL57 | 0.618366 | 3 | 0 | 3 |
| THNSL2 | VWA8 | 0.602092 | 3 | 0 | 3 |
| THNSL2 | SART1 | 0.594328 | 3 | 0 | 3 |
| THNSL2 | LTBP3 | 0.582358 | 5 | 0 | 3 |
| THNSL2 | C7orf26 | 0.573761 | 4 | 0 | 3 |
| THNSL2 | BPTF | 0.57365 | 4 | 0 | 3 |
| THNSL2 | TOE1 | 0.571999 | 4 | 0 | 3 |
| THNSL2 | DYNC1I1 | 0.570307 | 4 | 0 | 3 |
| THNSL2 | NELFCD | 0.564135 | 3 | 0 | 3 |
| THNSL2 | SV2B | 0.557439 | 5 | 0 | 3 |
| THNSL2 | LYPD6 | 0.5557 | 5 | 0 | 3 |
| THNSL2 | FLOT1 | 0.550244 | 5 | 0 | 4 |
| THNSL2 | RNF216 | 0.549524 | 6 | 0 | 3 |
| THNSL2 | WRAP73 | 0.545732 | 4 | 0 | 3 |
For details and further investigation, click here
