FLOT1

 

Full name: flotillin 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 6p21.33
Entrez ID: 10211 HGNC ID: HGNC:3757 Ensembl Gene: ENSG00000137312 OMIM ID: 606998
Drug and gene relationship at DGIdb

 

Expression of FLOT1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FLOT1 10211 208749_x_at 0.2839 0.4290
GSE20347 FLOT1 10211 210142_x_at 0.2247 0.1107
GSE23400 FLOT1 10211 208749_x_at 0.3736 0.0000
GSE26886 FLOT1 10211 210142_x_at 0.3232 0.1046
GSE29001 FLOT1 10211 210142_x_at 0.1426 0.5726
GSE38129 FLOT1 10211 208749_x_at 0.3082 0.0464
GSE45670 FLOT1 10211 210142_x_at 0.0951 0.5770
GSE53622 FLOT1 10211 44520 0.3689 0.0000
GSE53624 FLOT1 10211 44520 0.1780 0.0001
GSE63941 FLOT1 10211 210142_x_at 0.3048 0.4330
GSE77861 FLOT1 10211 208749_x_at 0.3394 0.1865
GSE97050 FLOT1 10211 A_23_P214603 0.2519 0.2684
SRP007169 FLOT1 10211 RNAseq 0.3245 0.3920
SRP008496 FLOT1 10211 RNAseq 0.3944 0.1027
SRP064894 FLOT1 10211 RNAseq 0.7451 0.0012
SRP133303 FLOT1 10211 RNAseq 0.2838 0.0245
SRP159526 FLOT1 10211 RNAseq 0.5567 0.0123
SRP193095 FLOT1 10211 RNAseq 0.3782 0.0007
SRP219564 FLOT1 10211 RNAseq 0.0920 0.8353
TCGA FLOT1 10211 RNAseq 0.0216 0.6279

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by FLOT1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FLOT1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FLOT1 10211 5 1 24
GSE20123 FLOT1 10211 5 1 24
GSE43470 FLOT1 10211 5 1 37
GSE46452 FLOT1 10211 1 10 48
GSE47630 FLOT1 10211 7 3 30
GSE54993 FLOT1 10211 2 1 67
GSE54994 FLOT1 10211 11 4 38
GSE60625 FLOT1 10211 0 1 10
GSE74703 FLOT1 10211 5 0 31
GSE74704 FLOT1 10211 2 0 18
TCGA FLOT1 10211 18 16 62

Total number of gains: 61; Total number of losses: 38; Total Number of normals: 389.  

 

Somatic mutations of FLOT1:

 

Generating mutation plots.

 

Highly correlated genes for FLOT1:

 

Showing top 20/322 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FLOT1ZDHHC40.676354303
FLOT1RAD51D0.671978404
FLOT1CASC150.646119303
FLOT1ASTN20.642716303
FLOT1GLI20.64196404
FLOT1GJA40.640399504
FLOT1SIRPB20.640239303
FLOT1ABL10.637242504
FLOT1CABYR0.627758303
FLOT1FKRP0.624364403
FLOT1AGPAT10.61919806
FLOT1IFITM20.618182706
FLOT1GRAMD1A0.617248504
FLOT1SMPDL3B0.614031403
FLOT1GALNT20.61298605
FLOT1ATRAID0.60194403
FLOT1HMG20B0.60129707
FLOT1FMNL10.601241403
FLOT1ELOVL50.599341404
FLOT1TSPAN180.597763303

For details and further investigation, click here