| Full name: latent transforming growth factor beta binding protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 4054 | HGNC ID: HGNC:6716 | Ensembl Gene: ENSG00000168056 | OMIM ID: 602090 |
| Drug and gene relationship at DGIdb | |||
Expression of LTBP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LTBP3 | 4054 | 219922_s_at | 0.4045 | 0.4477 | |
| GSE20347 | LTBP3 | 4054 | 219922_s_at | 0.3578 | 0.0883 | |
| GSE23400 | LTBP3 | 4054 | 219922_s_at | 0.0004 | 0.9978 | |
| GSE26886 | LTBP3 | 4054 | 219922_s_at | 1.0576 | 0.0028 | |
| GSE29001 | LTBP3 | 4054 | 219922_s_at | 0.5474 | 0.1637 | |
| GSE38129 | LTBP3 | 4054 | 219922_s_at | 0.2101 | 0.4460 | |
| GSE45670 | LTBP3 | 4054 | 219922_s_at | -0.3757 | 0.0658 | |
| GSE53622 | LTBP3 | 4054 | 2594 | -0.0364 | 0.7288 | |
| GSE53624 | LTBP3 | 4054 | 2594 | 0.1993 | 0.0191 | |
| GSE63941 | LTBP3 | 4054 | 219922_s_at | 0.1653 | 0.8798 | |
| GSE77861 | LTBP3 | 4054 | 227308_x_at | 0.1288 | 0.5668 | |
| GSE97050 | LTBP3 | 4054 | A_24_P298360 | -0.1333 | 0.6455 | |
| SRP007169 | LTBP3 | 4054 | RNAseq | 1.1071 | 0.0349 | |
| SRP008496 | LTBP3 | 4054 | RNAseq | 1.5284 | 0.0001 | |
| SRP064894 | LTBP3 | 4054 | RNAseq | 0.5076 | 0.1354 | |
| SRP133303 | LTBP3 | 4054 | RNAseq | -0.3516 | 0.1398 | |
| SRP159526 | LTBP3 | 4054 | RNAseq | 0.5196 | 0.1039 | |
| SRP193095 | LTBP3 | 4054 | RNAseq | 0.4552 | 0.0131 | |
| SRP219564 | LTBP3 | 4054 | RNAseq | 0.1655 | 0.8022 | |
| TCGA | LTBP3 | 4054 | RNAseq | -0.2136 | 0.0040 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by LTBP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LTBP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LTBP3 | 4054 | 8 | 5 | 17 | |
| GSE20123 | LTBP3 | 4054 | 8 | 5 | 17 | |
| GSE43470 | LTBP3 | 4054 | 4 | 1 | 38 | |
| GSE46452 | LTBP3 | 4054 | 11 | 3 | 45 | |
| GSE47630 | LTBP3 | 4054 | 7 | 5 | 28 | |
| GSE54993 | LTBP3 | 4054 | 3 | 0 | 67 | |
| GSE54994 | LTBP3 | 4054 | 7 | 5 | 41 | |
| GSE60625 | LTBP3 | 4054 | 0 | 3 | 8 | |
| GSE74703 | LTBP3 | 4054 | 3 | 0 | 33 | |
| GSE74704 | LTBP3 | 4054 | 6 | 3 | 11 | |
| TCGA | LTBP3 | 4054 | 23 | 7 | 66 |
Total number of gains: 80; Total number of losses: 37; Total Number of normals: 371.
Somatic mutations of LTBP3:
Generating mutation plots.
Highly correlated genes for LTBP3:
Showing top 20/202 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LTBP3 | LAT | 0.737664 | 3 | 0 | 3 |
| LTBP3 | ZNF526 | 0.697586 | 3 | 0 | 3 |
| LTBP3 | TMEM52 | 0.678418 | 3 | 0 | 3 |
| LTBP3 | WDR83 | 0.67534 | 3 | 0 | 3 |
| LTBP3 | ZNF639 | 0.672808 | 3 | 0 | 3 |
| LTBP3 | CPAMD8 | 0.671178 | 3 | 0 | 3 |
| LTBP3 | PLEKHG4 | 0.653068 | 3 | 0 | 3 |
| LTBP3 | ARL8A | 0.648586 | 3 | 0 | 3 |
| LTBP3 | USP51 | 0.645499 | 3 | 0 | 3 |
| LTBP3 | MAF1 | 0.634341 | 5 | 0 | 3 |
| LTBP3 | XCL1 | 0.629758 | 4 | 0 | 4 |
| LTBP3 | TMEM120B | 0.62924 | 5 | 0 | 3 |
| LTBP3 | GNB1L | 0.628175 | 3 | 0 | 3 |
| LTBP3 | PRPF8 | 0.62817 | 4 | 0 | 3 |
| LTBP3 | SLC27A1 | 0.620205 | 3 | 0 | 3 |
| LTBP3 | CCDC148 | 0.615761 | 4 | 0 | 4 |
| LTBP3 | HSD11B1L | 0.614612 | 4 | 0 | 3 |
| LTBP3 | C19orf12 | 0.613958 | 3 | 0 | 3 |
| LTBP3 | RHBDD3 | 0.613849 | 3 | 0 | 3 |
| LTBP3 | LRFN1 | 0.613357 | 3 | 0 | 3 |
For details and further investigation, click here
