| Full name: negative elongation factor complex member C/D | Alias Symbol: HSPC130|TH1|NELF-C|NELF-D | ||
| Type: protein-coding gene | Cytoband: 20q13.32 | ||
| Entrez ID: 51497 | HGNC ID: HGNC:15934 | Ensembl Gene: ENSG00000101158 | OMIM ID: 605297 |
Screen Evidence:
| |||
Expression of NELFCD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NELFCD | 51497 | 220607_x_at | 0.8303 | 0.0553 | |
| GSE20347 | NELFCD | 51497 | 220607_x_at | 0.6293 | 0.0004 | |
| GSE23400 | NELFCD | 51497 | 220607_x_at | 0.7422 | 0.0000 | |
| GSE26886 | NELFCD | 51497 | 225006_x_at | 0.2327 | 0.2188 | |
| GSE29001 | NELFCD | 51497 | 220607_x_at | 0.7433 | 0.0657 | |
| GSE38129 | NELFCD | 51497 | 220607_x_at | 0.7743 | 0.0000 | |
| GSE45670 | NELFCD | 51497 | 225006_x_at | 0.5328 | 0.0093 | |
| GSE53622 | NELFCD | 51497 | 62661 | 0.3724 | 0.0000 | |
| GSE53624 | NELFCD | 51497 | 62661 | 0.6762 | 0.0000 | |
| GSE63941 | NELFCD | 51497 | 220607_x_at | 1.6002 | 0.0007 | |
| GSE77861 | NELFCD | 51497 | 220607_x_at | 0.4514 | 0.0564 | |
| SRP007169 | NELFCD | 51497 | RNAseq | 0.1561 | 0.6215 | |
| SRP008496 | NELFCD | 51497 | RNAseq | 0.2994 | 0.0982 | |
| SRP064894 | NELFCD | 51497 | RNAseq | 0.5477 | 0.0056 | |
| SRP133303 | NELFCD | 51497 | RNAseq | 0.4855 | 0.0029 | |
| SRP159526 | NELFCD | 51497 | RNAseq | 0.7491 | 0.0427 | |
| SRP193095 | NELFCD | 51497 | RNAseq | 0.2859 | 0.0009 | |
| SRP219564 | NELFCD | 51497 | RNAseq | 0.6984 | 0.0369 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NELFCD expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NELFCD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NELFCD | 51497 | 14 | 2 | 14 | |
| GSE20123 | NELFCD | 51497 | 14 | 2 | 14 | |
| GSE43470 | NELFCD | 51497 | 13 | 0 | 30 | |
| GSE46452 | NELFCD | 51497 | 29 | 0 | 30 | |
| GSE47630 | NELFCD | 51497 | 24 | 1 | 15 | |
| GSE54993 | NELFCD | 51497 | 0 | 17 | 53 | |
| GSE54994 | NELFCD | 51497 | 29 | 0 | 24 | |
| GSE60625 | NELFCD | 51497 | 0 | 0 | 11 | |
| GSE74703 | NELFCD | 51497 | 11 | 0 | 25 | |
| GSE74704 | NELFCD | 51497 | 11 | 0 | 9 | |
| TCGA | NELFCD | 51497 | 43 | 4 | 49 |
Total number of gains: 188; Total number of losses: 26; Total Number of normals: 274.
Somatic mutations of NELFCD:
Generating mutation plots.
Highly correlated genes for NELFCD:
Showing top 20/1211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NELFCD | CSE1L | 0.802368 | 10 | 0 | 10 |
| NELFCD | CSTF1 | 0.764468 | 11 | 0 | 11 |
| NELFCD | TPX2 | 0.753816 | 10 | 0 | 10 |
| NELFCD | UBE2C | 0.737835 | 10 | 0 | 10 |
| NELFCD | PSMA7 | 0.732091 | 10 | 0 | 9 |
| NELFCD | AURKA | 0.711636 | 9 | 0 | 9 |
| NELFCD | CENPN | 0.709149 | 10 | 0 | 10 |
| NELFCD | SNRPB | 0.707374 | 10 | 0 | 10 |
| NELFCD | MCM2 | 0.702871 | 10 | 0 | 10 |
| NELFCD | GINS1 | 0.70248 | 11 | 0 | 9 |
| NELFCD | RUVBL1 | 0.697607 | 11 | 0 | 11 |
| NELFCD | PCNA | 0.696736 | 11 | 0 | 10 |
| NELFCD | CDCA5 | 0.696432 | 6 | 0 | 6 |
| NELFCD | ILF2 | 0.693649 | 10 | 0 | 9 |
| NELFCD | MYBL2 | 0.689716 | 10 | 0 | 10 |
| NELFCD | DSN1 | 0.688214 | 10 | 0 | 9 |
| NELFCD | CCT2 | 0.687268 | 10 | 0 | 10 |
| NELFCD | RAE1 | 0.68708 | 11 | 0 | 9 |
| NELFCD | PBK | 0.683873 | 10 | 0 | 10 |
| NELFCD | CENPM | 0.683752 | 9 | 0 | 9 |
For details and further investigation, click here
